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Profilin 1 maintains cell cycle fidelity to prevent unscheduled genome doubling and polyploidy in cancer

Federica Scotto di Carlo, Sharon Russo, Simon Gemble, et al.

Selected by 10 August 2026

Akshata Samel

Cancer Biology

Aging increases ovarian cancer growth, metastasis, and immunosuppression that can be alleviated by inhibiting hedgehog signaling

Asha Kumari, Mohamed Halaby Elbahoty, Resha Rajkarnikar, et al.

Selected by 03 August 2026

Zoha Sadaqat

Cancer Biology

Defective BRCA1-mediated DNA end resection drives tandem duplication formation and FANCM synthetic lethality

Namrata M. Nilavar, Alberto Marin-Gonzalez, Francesca Menghi, et al.

Selected by 23 June 2026

Marta San Martin

Molecular Biology

Telomeric antisense oligonucleotides reduce premature aging phenotypes in telomerase mutant zebrafish

Giulia Allavena, Francesca Rossiello, Aurora Irene Idilli, et al.

Selected by 13 June 2025

Jawdat Sandakly

Developmental Biology

Identification of neuron-glia signaling feedback in human schizophrenia using patient-derived, mix-and-match forebrain assembloids

Eunjee Kim, Yunhee Kim, Soojung Hong, et al.

Selected by 12 June 2025

Justine Gromaire et al.

Neuroscience

Deletion of PIEZO1 in adult cardiomyocytes accelerates cardiac aging and causes premature death

Ze-Yan Yu, Yang Guo, Scott Kesteven, et al.

Selected by 17 March 2025

Theodora Stougiannou

Cell Biology

HIF1A contributes to the survival of aneuploid and mosaic pre-implantation embryos

Estefania Sanchez-Vasquez, Marianne E. Bronner, Magdalena Zernicka-Goetz

Selected by 11 October 2024

Anchel De Jaime Soguero

Developmental Biology

Integrin conformation-dependent neutrophil slowing obstructs the capillaries of the pre-metastatic lung in a model of breast cancer

Frédéric Fercoq, Gemma S. Cairns, Marco De Donatis, et al.

Selected by 07 October 2024

Simon Cleary

Cancer Biology

LincRNAs enable germ cells differentiation by promoting PUF proteins condensation

Roni Falk, Noa Gilad, Hanna Achache, et al.

Selected by 30 October 2023

Umutcan Kaan Bozan et al.

Developmental Biology

CRISPR-dependent base editing screens identify separation of function mutants of RADX with altered RAD51 regulatory activity

Madison B. Adolph, Atharv S. Garje, Swati Balakrishnan, et al.

Selected by 06 September 2023

Jessica Chevallier, Pierre Caron

Cell Biology

Glioblastoma extracellular vesicles influence glial cell hyaluronic acid deposition to promote invasiveness

Dominik Koessinger, David Novo, Anna Koessinger, et al.

Selected by 13 June 2023

Jade Chan

Cancer Biology

Inhibition of Centrosome Clustering Reduces Cystogenesis and Improves Kidney Function in Autosomal Dominant Polycystic Kidney Disease

Tao Cheng, Aruljothi Mariappan, Ewa Langner, et al.

Selected by 24 April 2023

Fiona Macleod