Search results

Organoid Easytag: an efficient workflow for gene targeting in human organoids

Dawei Sun, Lewis D. Evans, Emma L. Rawlins

Selected by 22 May 2020

Kirsty Ferguson

An NKX2-1/ERK/WNT feedback loop modulates gastric identity and response to targeted therapy in lung adenocarcinoma

Rediet Zewdu, Elnaz Mirzaei Mehrabad, Kelley Ingram, et al.

Selected by 10 May 2020

Catherine Dabrowska

Discussion

Parallel CRISPR-Cas9 screens clarify impacts of p53 on screen performance

Anne Ramsay Bowden, David A. Morales Juarez, Matylda Sczaniecka-Clift, et al.

Selected by 27 April 2020

Mila Basic

Drug mechanism-of-action discovery through the integration of pharmacological and CRISPR screens

Emanuel Gonçalves, Aldo Segura-Cabrera, Clare Pacini, et al.

Selected by 20 March 2020

Georgina Sava

Akt/Foxo pathway activation switches apoptosis to senescence in short telomere zebrafish

Mounir El-Maï, Marta Marzullo, Inês Pimenta de Castro, et al.

Selected by 21 January 2020

Lorenzo Lafranchi

Identification of neural oscillations and epileptiform changes in human brain organoids

Ranmal A. Samarasinghe, Osvaldo A. Miranda, Simon Mitchell, et al.

Selected by 25 November 2019

Theresa Pohlkamp

Senescence of alveolar stem cells drives progressive pulmonary fibrosis

Changfu Yao, Xiangrong Guan, Gianni Carraro, et al.

Selected by 08 November 2019

Rob Hynds

Negative Regulation of Autophagy by UBA6-BIRC6–Mediated Ubiquitination of LC3

Rui Jia, Juan S. Bonifacino

Selected by 18 July 2019

Sandra Malmgren Hill

Discussion

Myc instructs and maintains pancreatic adenocarcinoma phenotype

Nicole M Sodir, Roderik M Kortlever, Valentin JA Barthet, et al.

Selected by 08 March 2019

William Hill

Discussion

Variability of bacterial behavior in the mammalian gut captured using a growth-linked single-cell synthetic gene oscillator

David T Riglar, David L Richmond, Laurent Potvin-Trottier, et al.

Selected by 25 January 2019

Meng Zhu

Discussion

Inter-organ growth coordination is mediated by the Xrp1/Dilp8 axis in Drosophila

Laura Boulan, Ditte Andersen, Julien Colombani, et al.

Selected by 06 January 2019

Alberto Rosello-Diez

Discussion

Basal extrusion drives cell invasion and mechanical stripping of E-cadherin

John Fadul, Gloria M Slattum, Nadja M Redd, et al.

Selected by 02 January 2019

William Hill

Discussion