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The genetic basis of novel trait gain in walking fish

Amy L Herbert, Corey AH Allard, Matthew J McCoy, et al.

Discussion

Nanos2+ cells give rise to germline and somatic lineages in the sea anemone Nematostella vectensis

Andreas Denner, Julia Steger, Alexander Ries, et al.

2D and 3D multiplexed subcellular profiling of nuclear instability in human cancer

Shannon Coy, Brian Cheng, Jong Suk Lee, et al.

Discussion

patterned embryonic invagination evolved in response to mechanical instability

Bruno C. Vellutini, Marina B. Cuenca, Abhijeet Krishna, et al.

AND

Divergent evolutionary strategies preempt tissue collision in fly gastrulation

Bipasha Dey, Verena Kaul, Girish Kale, et al.

Spastin locally amplifies microtubule dynamics to pattern the axon for presynaptic cargo delivery

Jayne Aiken, Erika L. F. Holzbaur

Discussion

Inference of drug off-target effects on cellular signaling using Interactome-Based Deep Learning

Nikolaos Meimetis, Douglas A. Lauffenburger, Avlant Nilsson

Structured RhoGEF recruitment drives myosin II organization on large exocytotic vesicles

Kumari Kamalesh, Dagan Segal, Ori Avinoam, et al.

Effects of Aerobic Exercise in Hepatic Lipid Droplet-Mitochondria interaction in Non-alcoholic Fatty Liver Disease

Juan Carlos Bórquez, Francisco Díaz-Castro, Francisco Pino-de La Fuente, et al.

Discussion

Metabolomic profiling reveals effects of marein on energy metabolism in HepG2 cells

Baoping Jiang, Liang Le,, Keping Hu, et al.

Discussion

The genome of the colonial hydroid Hydractinia reveals their stem cells utilize a toolkit of evolutionarily shared genes with all animals

Christine E. Schnitzler, E. Sally Chang, Justin Waletich, et al.

Similarity metric learning on perturbational datasets improves functional identification of perturbations

Ian Smith, Petr Smirnov, Benjamin Haibe-Kains

Generating human neural diversity with a multiplexed morphogen screen in organoids

Neal D. Amin, Kevin W. Kelley, Jin Hao, et al.