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Small Molecule Agonists of TREM2 Reprogram Microglia and Protect Synapses in Human Alzheimer’s Models

Hossam Nada, Shaoren Yuan, Farida El Gaamouch, et al.

Selected by 17 March 2026

Dina Kabbara

Pharmacology and Toxicology

PPARδ activation in microglia drives a transcriptional response that primes phagocytic function while countering inflammatory activation

Jacob S. Deyell, Jonathan Hasselmann, Linda Stroud, et al.

Selected by 11 February 2026

Isabel Paine

Neuroscience

A Novel Chimeric Antigen Receptor (CAR) - Strategy to Target EGFRVIII-Mutated Glioblastoma Cells via Macrophages

Kristi Vera, Gülen Esken, Jin Wook Hwang, et al.

Selected by 21 January 2026

Dina Kabbara

Cancer Biology

TAM receptors control actomyosin dynamics in osteoclasts via RHOA-COFILIN-MYOSIN II signaling

Janik Engelmann, Jennifer Zarrer, Max Schmerder, et al.

Selected by 14 October 2025

André Luiz Amorim Costa, Marcus Oliveira

Immunology

Pediatric cerebrospinal fluid immune profiling distinguishes pediatric-onset multiple sclerosis from other pediatric-onset acute neurological disorders

Diego A. Espinoza , Tobias Zrzavy, Gautier Breville, et al.

Selected by 02 July 2025

alaferdi et al.

Immunology

Prenatal exposure to environmental stressors alters gut macrophage development and gastrointestinal function of male offspring

Dang M. Nguyen, Sarah K. Monroe, Danielle N. Rendina, et al.

Selected by 09 April 2025

Jeny Jose

Developmental Biology

Target cell tension regulates macrophage trogocytosis

Caitlin E. Cornell, Aymeric Chorlay, Deepak Krishnamurthy, et al.

Selected by 04 January 2025

Felipe Del Valle Batalla

Biophysics

Triglyceride metabolism controls inflammation and APOE4-associated disease states in microglia

Roxan A. Stephenson, Kory R. Johnson, Linling Cheng, et al.

Selected by 22 August 2024

Gustavo Stelzer, Marcus Oliveira

Biochemistry

Aspergillus dsRNA virus drives fungal fitness and pathogenicity in the mammalian host

Vanda Lerer, Marina Rocha, John Adeoye, et al.

Selected by 13 May 2024

UofA IMB565 et al.

Microbiology

Fetal brain response to maternal inflammation requires microglia

Bridget Elaine LaMonica Ostrem, Nuria Dominguez Iturza, Jeffrey Stogsdill, et al.

Selected by 24 April 2024

Manuel Lessi

Neuroscience

NAD(H) homeostasis is essential for host protection mediated by glycolytic myeloid cells in tuberculosis

Hayden T. Pacl, Krishna C. Chinta, Vineel P. Reddy, et al.

Selected by 16 October 2023

Matheus Atella de Oliveira, Marcus Oliveira

Biochemistry

Glycan-specific IgM is critical for human immunity to Staphylococcus aureus

Astrid Hendriks, Priscilla F. Kerkman, Meri R.J. Varkila, et al.

Selected by 10 August 2023

Lucy Bowden

Immunology