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Distinct activities of Scrib module proteins organize epithelial polarity

Mark J. Khoury, David Bilder

AND

Lgl cortical dynamics are independent of binding to the Scrib-Dlg complex but require Dlg-dependent restriction of aPKC

Guilherme Ventura, Sofia Moreira, André Barros-Carvalho, et al.

Selected by 13 January 2020

Helen Zenner

Developmental Biology

The Rab5-Rab11 endosomal pathway is required for BDNF-induced CREB transcriptional regulation in neurons

Andrés G. González, Oscar M. Lazo, Francisca C. Bronfman

Selected by 20 December 2019

Theresa Pohlkamp

Neuroscience

Rab11A regulates the constitutive secretory pathway during Toxoplasma gondii invasion of host cells and parasite replication

Venugopal Kannan, Chehade Sylia, Werkmeister Elisabeth, et al.

Selected by 18 December 2019

Mariana De Niz

Cell Biology

ULK complex organization in autophagy by a C-shaped FIP200 N-terminal domain dimer

Xiaoshan Shi, Adam L. Yokom, Chunxin Wang, et al.

Selected by 17 December 2019

Sandra Malmgren Hill

Biochemistry

Rab11b-mediated integrin recycling promotes brain metastatic adaptation and outgrowth

Erin N. Howe, Miranda D. Burnette, Melanie E. Justice, et al.

Selected by 19 July 2019

Beverley Wilson

Biochemistry

Negative Regulation of Autophagy by UBA6-BIRC6–Mediated Ubiquitination of LC3

Rui Jia, Juan S. Bonifacino

Selected by 18 July 2019

Sandra Malmgren Hill

Cell Biology

Spontaneous isomerization of long-lived proteins provides a molecular mechanism for the lysosomal failure observed in Alzheimer’s disease

Tyler R. Lambeth, Dylan L. Riggs, Lance E. Talbert, et al.

Selected by 15 May 2019

Joanna Cross

Biochemistry

Spastin tethers lipid droplets to peroxisomes and directs fatty acid trafficking through ESCRT-III

Chi-Lun Chang, Aubrey V. Weigel, Maria S. Ioannou, et al.

Selected by 22 April 2019

Pablo Ranea Robles

Cell Biology

The autophagic membrane tether ATG2A transfers lipids between membranes

Shintaro Maeda, Chinatsu Otomo, Takanori Otomo

Selected by 12 April 2019

Sandra Malmgren Hill

Cell Biology

Engineered Enzymes that Retain and Regenerate their Cofactors Enable Continuous-Flow Biocatalysis

Carol J. Hartley, Charlotte C. Williams, Judith A. Scoble, et al.

Selected by 22 March 2019

Zhang-He Goh

Synthetic Biology

SorCS1-mediated Sorting of Neurexin in Dendrites Maintains Presynaptic Function

Luis Filipe Ribeiro, Ben Verpoort, Julie Nys, et al.

Selected by 27 February 2019

Carmen Adriaens

Cell Biology

ENDOSOMAL MEMBRANE TENSION CONTROLS ESCRT-III-DEPENDENT INTRA-LUMENAL VESICLE FORMATION

Vincent Mercier, Jorge Larios, Guillaume Molinard, et al.

Selected by 26 February 2019

Nicola Stevenson

Biophysics