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Accelerated erythrocyte senescence causes dose-limiting anemia of antimalarial enolase inhibitors

Andrew J. Jezewski, Yu-Hsi Lin, Julie A. Reisz, et al.

Discussion

Small molecules exploiting structural differences within microRNA-200 precursors family members reverse a type 2 diabetes phenotype

Hafeez S. Haniff, Xiaohui Liu, Laurent Knerr, et al.

Discussion

Genome-wide CRISPRi/a screens in human neurons link lysosomal failure to ferroptosis

Ruilin Tian, Anthony Abarientos, Jason Hong, et al.

Toll-like receptor 4 is activated by platinum and contributes to cisplatin-induced ototoxicity

Ghazal Babolmorad, Asna Latif, Niall M. Pollock, et al.

AND

Application of the in vivo oxidative stress reporter Hmox1 as mechanistic biomarker of arsenic toxicity

Francisco Inesta-Vaquera, Panida Navasumrit, Colin J. Henderson, et al.

Discussion

Electron Transfer from Cytochrome P450 Reductase to Cytochrome P450: Towards a Structural and Dynamic Understanding

Goutam Mukherjee, Prajwal P. Nandekar, Rebecca C. Wade

Discussion

PINK1 and parkin shape the organism-wide distribution of a deleterious mitochondrial genome

Arnaud Ahier, Nadia Cummins, Chuan-Yang Dai, et al.

Mitochondrial fatty acid synthesis coordinates mitochondrial oxidative metabolism

Sara M. Nowinski, Ashley Solmonson, Scott F. Rusin, et al.

Mitochondrial fission factor (MFF) is a critical regulator of peroxisome maturation

Josiah B. Passmore, Ruth E. Carmichael, Tina A. Schrader, et al.

Lis1 regulates Phagocytosis by co-localising with actin in the Phagocytic cup

Aditya Chhatre, Paulomi Sanghavi, Roop Mallik

Discussion

Small molecules for modulating protein driven liquid-liquid phase separation in treating neurodegenerative disease

Richard J. Wheeler, Hyun O. Lee, Ina Poser, et al.

Oncogenic hijacking of a developmental transcription factor evokes therapeutic vulnerability for ROS-induction in Ewing sarcoma

Aruna Marchetto, Shunya Ohmura, Martin F. Orth, et al.

Discussion

TTL proteins scaffold brassinosteroid signaling components at the plasma membrane to optimize signal transduction in plant cells

Vitor Amorim-Silva, Alvaro Garcia-Moreno, Araceli G Castillo, et al.