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SLC19A1 is a cyclic dinucleotide transporter

Rutger Luteijn, Shivam Zaver, Benjamin G Gowen, et al.

AND

SLC19A1 is an importer of the immunotransmitter cGAMP

Anthony F. Cordova, Christopher Ritchie, Gaelen T. Hess, et al.

AND

2'3'-cGAMP is an immunotransmitter produced by cancer cells and regulated by ENPP1

Jacqueline A Carozza, Volker Boehnert, Kelsey E Shaw, et al.

Discussion

Structures of the Otopetrin Proton Channels Otop1 and Otop3

Kei Saotome, Bochuan Teng, Che Chun (Alex) Tsui, et al.

Discussion

Central spindle microtubules are strongly coupled to chromosomes during both anaphase A and anaphase B

Che-Hang Yu, Stefanie Redemann, Hai-Yin Wu, et al.

Cell growth dilutes the cell cycle inhibitor Rb to trigger cell division

Evgeny Zatulovskiy, Daniel F. Berenson, Benjamin R. Topacio, et al.

Quantification of microenvironmental metabolites in murine cancer models reveals determinants of tumor nutrient availability

Mark R Sullivan, Laura V Danai, Caroline A Lewis, et al.

Applications of Machine Learning in Decision Analysis for Dose Management for Dofetilide

Andrew E Levy, Minakshi Biswas, Rachel Weber, et al.

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Optimal Scheduling of Bevacizumab and Pemetrexed/Cisplatin Dosing in Non-Small Cell Lung Cancer

Benjamin Schneider, Arnaud Boyer, Joseph Ciccolini, et al.

Discussion

Lineage tracing on transcriptional landscapes links state to fate during differentiation

Caleb Weinreb, Alejo E Rodriguez-Fraticelli, Fernando D Camargo, et al.

Distinct ROPGEFs successively drive polarization and outgrowth of root hairs

Philipp Denninger, Anna Reichelt, Vanessa Aphaia Fiona Schmidt, et al.

Discussion

Minimal membrane interactions conferred by Rheb C-terminal farnesylation are essential for mTORC1 activation

Shawn M Ferguson, Brittany Angarola

Mechanical Stretch Kills Transformed Cancer Cells

Ajay Tijore, Mingxi Yao, Yu-Hsiu Wang, et al.

Discussion

Regulation of modulatory cell activity across olfactory structures in Drosophila melanogaster

Xiaonan Zhang, Kaylynn Coates, Andrew Dacks, et al.

A direct and widespread role for the nuclear receptor EcR in mediating the response to ecdysone in Drosophila

Christopher M Uyehara, Daniel J McKay

Discussion