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Drug use in special populations

Any drugs that are being used in special populations: Patients with liver and kidney failure, in paediatrics, in geriatrics, and in pregnant or lactating patients. Includes the discovery of factors that could potentially affect drug use in these special populations.

 



List by Zhang-He Goh

Apicomplexan F-actin is required for efficient nuclear entry during host cell invasion

Mario Del Rosario, Javier Periz, Georgios Pavlou, et al.

Selected by 04 June 2019

Juan Quintana

Microbiology

Benchmarking Single-Cell RNA Sequencing Protocols for Cell Atlas Projects

Elisabetta Mereu, Atefeh Lafzi, Catia Moutinho, et al.

AND

Systematic comparative analysis of single cell RNA-sequencing methods

Jiarui Ding, Xian Adiconis, Sean K. Simmons, et al.

Selected by 01 June 2019

Rob Hynds

Bioinformatics

Intestinal peroxisomal fatty acid β-oxidation regulates neural serotonin signaling through a feedback mechanism

Aude Bouagnon, Shubhi Srivastava, Oishika Panda, et al.

Selected by 29 May 2019

Pablo Ranea Robles

Neuroscience

Actin chromobody imaging reveals sub-organellar actin dynamics

Cara Schiavon, Tong Zhang, Leonardo Andrade, et al.

Selected by 24 May 2019

Mariana De Niz

Cell Biology

A large-scale resource for tissue-specific CRISPR mutagenesis in Drosophila

Fillip Port, Claudia Strein, Mona Stricker, et al.

Selected by 23 May 2019

Gabriel Aughey

Genetics

Developmentally regulated Shh expression is robust to TAD perturbations

Iain Williamson, Lauren Kane, Paul S. Devenney, et al.

Selected by 21 May 2019

Jesus Victorino

Genetics

Shake-it-off: A simple ultrasonic cryo-EM specimen preparation device

John L. Rubinstein, Hui Guo, Zev A. Ripstein, et al.

Selected by 21 May 2019

David Wright

Biochemistry

WASP restricts active Rac to maintain cells’ front-rear polarisation

Clelia Amato, Peter Thomason, Andrew Davidson, et al.

Selected by 21 May 2019

Vibha SINGH

Cell Biology

Spontaneous isomerization of long-lived proteins provides a molecular mechanism for the lysosomal failure observed in Alzheimer’s disease

Tyler R. Lambeth, Dylan L. Riggs, Lance E. Talbert, et al.

Selected by 15 May 2019

Joanna Cross

Biochemistry

specific Disruption of Established P. aeruginosa Biofilms Using Polymer-Attacking Enzymes

Kristin N. Kovach, Derek Fleming, Kendra P. Rumbaugh, et al.

Selected by 14 May 2019

Snehal Kadam

Microbiology

Intravital optoacoustic ultrasound bio-microscopy reveals radiation-inhibited skull angiogenesis

Hector Estrada, Johannes Rebling, Wolfgang Sievert, et al.

Selected by 13 May 2019

Mariana De Niz

Biophysics