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Induction of cortical Par complex polarity by designed proteins causes cytoskeletal symmetry breaking in unpolarized mammalian cells

Joseph L. Watson, Ariel J. Ben-Sasson, Alice Bittleston, et al.

Selected by Ines Jmel-Boyer

ATM-dependent formation of a novel chromatin compartment regulates the Response to DNA Double Strand Breaks and the biogenesis of translocations

Coline Arnould, Vincent Rocher, Aldo S. Bader, et al.

Selected by Jennifer Ann Black

The roles of distinct Ca2+ signaling mediated by Piezo and inositol triphosphate receptor (IP3R) in the remodeling of E-cadherin during cell dissemination

Alejandra J.H. Cabrera, Barry M. Gumbiner, Young V. Kwon

Selected by Holly Smith

Analysis of science journalism reveals gender and regional disparities in coverage

Natalie R. Davidson, Casey S. Greene

Selected by Helen Robertson

Epithelial-mesenchymal plasticity determines estrogen receptor positive (ER+) breast cancer dormancy and reacquisition of an epithelial state drives awakening

Patrick Aouad, Yueyun Zhang, Céline Stibolt, et al.

Selected by Sagar Varankar

Inflammatory blockade prevents injury to the developing pulmonary gas exchange surface in preterm primates

Andrea Toth, Shelby Steinmeyer, Paranthaman Kannan, et al.

Selected by Sagar Varankar

Mechanosensitivity of amoeboid cells crawling in 3D

Florian Gaertner, Patricia Reis-Rodrigues, Ingrid de Vries, et al.

Selected by Jessica L. Teo

A “spindle and thread”-mechanism unblocks translation of N-terminally disordered proteins

Margit Kaldmäe, Thibault Vosselman, Xueying Zhong, et al.

Selected by Utrecht Protein Folding and Assembly

The Design, Synthesis, and Evaluation of Hypoxia-Activated Prodrugs of the KDAC Inhibitor Panobinostat

Ewen Calder, Anna Skwarska, Deborah Sneddon, et al.

Selected by Zhang-He Goh

Interactive design of GPU-accelerated Image Data Flow Graphs and cross-platform deployment using multi-lingual code generation

Robert Haase, Akanksha Jain, Stéphane Rigaud, et al.

Selected by Mariana De Niz

Deep Learning Enables Individual Xenograft Cell Classification in Histological Images by Analysis of Contextual Features

Quentin Juppet, Fabio De Martino, Martin Weigert, et al.