Impaired 26S proteasome causes learning and memory deficiency and induces neuroinflammation mediated by NF-κB in mice
Selected by
22 August 2024
Gustavo Stelzer, Marcus Oliveira
TAK1 operates at the primary cilium in non-canonical TGFB/BMP signaling to control heart development
Selected by
16 August 2024
Reinier Prosee
Membrane Curvature Promotes ER-PM Contact Formation via Junctophilin-EHD Interactions
Selected by
07 August 2024
Barbora Knotkova
Autism gene variants disrupt enteric neuron migration and cause gastrointestinal dysmotility
Selected by
10 June 2024
Rachel Mckeown
A complex Plasmodium falciparum cryptotype circulating at low frequency across the African continent
Selected by
03 April 2024
Alejandra Herbert Leffler's Lab
Behavioral screening of conserved RNA-binding proteins reveals CEY-1/YBX RNA-binding protein dysfunction leads to impairments in memory and cognition
Selected by
15 February 2024
Chee Kiang Ewe
Invasion of glioma cells through confined space requires membrane tension regulation and mechano-electrical coupling via Plexin-B2
Selected by
13 February 2024
Jade Chan
Multi-pass, single-molecule nanopore reading of long protein strands with single-amino acid sensitivity
Selected by
04 December 2023
Benjamin Dominik Maier, Samantha Seah
Short N-terminal disordered regions and the proline-rich domain are major regulators of phase transitions for full-length UBQLN1, UBQLN2 and UBQLN4
Selected by
22 October 2023
Aniruddha Das
CRISPR-dependent base editing screens identify separation of function mutants of RADX with altered RAD51 regulatory activity
Selected by
06 September 2023
Jessica Chevallier, Pierre Caron
Proteasome condensate formation is driven by multivalent interactions with shuttle factors and K48-linked ubiquitin chains
Selected by
05 September 2023
Aniruddha Das
Glycan-specific IgM is critical for human immunity to Staphylococcus aureus
Selected by
10 August 2023
Lucy Bowden