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CRISPR-dependent base editing screens identify separation of function mutants of RADX with altered RAD51 regulatory activity

Madison B. Adolph, Atharv S. Garje, Swati Balakrishnan, et al.

Selected by Jessica Chevallier, Pierre Caron

Proteasome condensate formation is driven by multivalent interactions with shuttle factors and K48-linked ubiquitin chains

Kenrick A. Waite, Gabrielle Vontz, Stella Y. Lee, et al.

Selected by Aniruddha Das

Glycan-specific IgM is critical for human immunity to Staphylococcus aureus

Astrid Hendriks, Priscilla F. Kerkman, Meri R.J. Varkila, et al.

Selected by Lucy Bowden

Conserved cardiolipin-mitochondrial ADP/ATP carrier interactions assume distinct structural and functional roles that are clinically relevant

Nanami Senoo, Dinesh K. Chinthapalli, Matthew G. Baile, et al.

Selected by Barbora Knotkova

A transposase-derived gene required for human brain development

Luz Jubierre Zapater, Elias Rodriguez-Fos, Merce Planas-Felix, et al.

Selected by Amanda Ivanoff

EXO1-mediated DNA repair by single-strand annealing is essential for BRCA1-deficient cells

B. van de Kooij, A. Schreuder, R.S. Pavani, et al.

Selected by Jennifer Ann Black

daf-42 is an evolutionarily young gene essential for dauer development in Caenorhabditis elegans

Daisy S. Lim, Jun Kim, Wonjoo Kim, et al.

Selected by Chee Kiang Ewe

Embryo mechanics cartography: inference of 3D force atlases from fluorescence microscopy

Sacha Ichbiah, Fabrice Delbary, Alex McDougall, et al.

Selected by Girish Kale

Phospho-seq: Integrated, multi-modal profiling of intracellular protein dynamics in single cells

John D. Blair, Austin Hartman, Fides Zenk, et al.

Selected by Benjamin Dominik Maier

3D genome organization around nuclear speckles drives mRNA splicing efficiency

Prashant Bhat, Amy Chow, Benjamin Emert, et al.

Selected by Diego Martínez

Restructuring of an asymmetric neural circuit during associative learning

Leo T.H. Tang, Garrett A. Lee, Steven J. Cook, et al.