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The molecular structure of primary cilia revealed by cryo-electron tomography

Petra Kiesel, Gonzalo Alvarez Viar, Nikolai Tsoy, et al.

Selected by 06 April 2020

Nicola Stevenson

Biochemistry

An asymmetry in the frequency and position of mitosis in the epiblast precedes gastrulation and suggests a role for mitotic rounding in cell delamination during primitive streak epithelial-mesenchymal transition

Evangéline Despin-Guitard, Navrita Mathiah, Matthew Stower, et al.

Selected by 12 March 2020

Claire Simon & Sophie Morgani

Loss of epithelial polarity redirects Notch signaling and triggers a Xrp1 response during neoplastic growth in Drosophila

Rémi Logeay, Charles Géminard, Patrice Lassus, et al.

Selected by 27 February 2020

Sally Lowell

Developmental Biology

Membrane tension mediated mechanotransduction drives fate choice in embryonic stem cells

Henry De Belly, Philip H. Jones, Ewa K. Paluch, et al.

AND

Cell surface mechanics gate stem cell differentiation

Martin Bergert, Sergio Lembo, Danica Milovanović, et al.

Selected by 25 February 2020

Joseph Jose Thottacherry

Biophysics

Chemogenetic analysis of how receptors for short chain fatty acids regulate the gut-brain axis

Natasja Barki, Daniele Bolognini, Ulf Börjesson, et al.

Selected by 25 February 2020

Phyllis Phuah

Biochemistry

Hedgehog signaling is required for endomesodermal patterning and germ cell development in Nematostella vectensis

Cheng-Yi Chen, Sean A. McKinney, Lacey R. Ellington, et al.

Selected by 25 February 2020

Paul Gerald L. Sanchez and Stefano Vianello

Developmental Biology

Architecture of the AP2:clathrin coat on the membranes of clathrin-coated vesicles

Oleksiy Kovtun, Veronica Kane Dickson, Bernard T. Kelly, et al.

AND

The Structures of Natively Assembled Clathrin Coated Vesicles

Mohammadreza Paraan, Joshua Mendez, Savanna Sharum, et al.

Selected by 24 February 2020

Stephen Royle

Cell Biology

On-demand spatiotemporal programming of collective cell migration via bioelectric stimulation

Tom J. Zajdel, Gawoon Shim, Linus Wang, et al.

Selected by 23 February 2020

Mariana De Niz

Biophysics

Obesity-driven changes in ECM composition promote local invasion and metastasis of breast tumors

Andrew Wishart, Yifan Peng, Sydney Conner, et al.

Selected by 11 February 2020

Vassilis Papalazarou, Anh Hoang Le

Cancer Biology

Coupled active systems encode emergent behavioral dynamics of the unicellular predator Lacrymaria olor

Scott M. Coyle, Ellie M. Flaum, Hongquan Li, et al.

Selected by 29 January 2020

Mariana De Niz

Biophysics

Growth factor-mediated coupling between lineage size and cell fate choice underlies robustness of mammalian development

Néstor Saiz, Laura Mora-Bitria, Shahadat Rahman, et al.

Selected by 19 January 2020

Pierre Osteil, Irepan Salvador-Martinez

Developmental Biology

Species-specific developmental timing is associated with global differences in protein stability in mouse and human

Teresa Rayon, Despina Stamataki, Ruben Perez-Carrasco, et al.

Selected by 16 January 2020

Irepan Salvador-Martinez

Developmental Biology
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