My name is Mariana De Niz. I am a postdoctoral fellow at the Institute of Molecular Medicine in Lisbon, Portugal. My work focuses on understanding the biophysics and dynamics of the parasite Trypanosoma brucei (causative of sleeping sickness), in various tissues of mammalian hosts. I am particularly interested in microscopy methods to image host-parasite interactions, and am keen on developing new methods that enable visualising and investigating these interactions. In my PhD and first postdoc, I worked on investigating various stages of the malaria-causative parasite Plasmodium. I was particularly interested in understanding parasite tropism and mechanisms of sequestration during Plasmodium blood stages, and host cell organelle manipulation during Plasmodium liver stage development.
Role for the flagellum attachment zone in the resolution of cell membrane morphogenesis during Leishmania cell division
Mariana De Niz
Extended depth of focus multiphoton microscopy via incoherent pulse splitting
Mariana De Niz
Light microscopy of proteins in their ultrastructural context
Mariana De Niz
The single flagellum of Leishmania has a fixed polarisation of its asymmetric beat
Mariana De Niz
Circumvention of common labeling artifacts using secondary nanobodies
Mariana De Niz
Constricted migration contributes to persistent 3D genome structure changes associated with an invasive phenotype in melanoma cells
Mariana De Niz
Tissue size controls patterns of cell proliferation and migration in freely-expanding epithelia
Mariana De Niz
Robotic microscopy for everyone: the OpenFlexure Microscope
Mariana De Niz
ZeroCostDL4Mic: an open platform to simplify access and use of Deep-Learning in Microscopy
Mariana De Niz
A high-affinity antibody against the CSP N-terminal domain lacks Plasmodium falciparum inhibitory activity
Mariana De Niz
Super-Beacons: open-source probes with spontaneous tuneable blinking compatible with live-cell super-resolution microscopy
Mariana De Niz
vLUME: 3D Virtual Reality for Single-molecule Localization Microscopy
Mariana De Niz