My name is Mariana De Niz. I am a postdoctoral fellow at the Institute of Molecular Medicine in Lisbon, Portugal. My work focuses on understanding the biophysics and dynamics of the parasite Trypanosoma brucei (causative of sleeping sickness), in various tissues of mammalian hosts. I am particularly interested in microscopy methods to image host-parasite interactions, and am keen on developing new methods that enable visualising and investigating these interactions. In my PhD and first postdoc, I worked on investigating various stages of the malaria-causative parasite Plasmodium. I was particularly interested in understanding parasite tropism and mechanisms of sequestration during Plasmodium blood stages, and host cell organelle manipulation during Plasmodium liver stage development.
Miniaturized Devices for Bioluminescence Imaging in Freely Behaving Animals
20 years of African Neuroscience: Waking a sleeping giant
Breaking the next Cryo-EM resolution barrier – Atomic resolution determination of proteins!
Glycocalyx-mediated Cell Adhesion and Migration
A hydraulic instability drives the cell death decision in the nematode germline
Tension causes structural unfolding of intracellular intermediate filaments
A Method to sort heterogenous cell populations based on migration in 2D and 3D environments
Trackosome: a computational toolbox to study the spatiotemporal dynamics of centrosomes, nuclear envelope and cellular membrane
Practical Fluorescence Reconstruction Microscopy for Large Samples and Low-Magnification Imaging
Algorithms for the selection of fluorescent reporters
Insights into the salivary N-glycome of Lutzomyia longipalpis, vector of visceral leishmaniasis
LFA-1 signals to promote actin polymerization and upstream migration in T cells