My name is Mariana De Niz. I am a postdoctoral fellow at the Institute of Molecular Medicine in Lisbon, Portugal. My work focuses on understanding the biophysics and dynamics of the parasite Trypanosoma brucei (causative of sleeping sickness), in various tissues of mammalian hosts. I am particularly interested in microscopy methods to image host-parasite interactions, and am keen on developing new methods that enable visualising and investigating these interactions. In my PhD and first postdoc, I worked on investigating various stages of the malaria-causative parasite Plasmodium. I was particularly interested in understanding parasite tropism and mechanisms of sequestration during Plasmodium blood stages, and host cell organelle manipulation during Plasmodium liver stage development.
Spatial heterogeneity of cell-matrix adhesive forces predicts human glioblastoma migration
A subcellular atlas of Toxoplasma reveals the functional context of the proteome
EllipTrack: A Global-Local Cell-Tracking Pipeline for 2D Fluorescence Time-Lapse Microscopy
Temporal correlation between oscillating force dipoles drives single cell migration in 3D
Intraflagellar transport during the assembly of flagella of different length in Trypanosoma brucei isolated from tsetse flies
PlanktonScope: Affordable modular imaging platform for citizen oceanography
Self-organized patterning of cell morphology via mechanosensitive feedback
BiteOscope: an open platform to study mosquito blood-feeding behavior
Functional MRI of large scale activity in behaving mice
Utah-Stanford Ventilator (Vent4US): Developing a rapidly scalable ventilator for COVID-19 patients with ARDS
A transient CRISPR/Cas9 expression system for genome editing in Trypanosoma brucei.