My name is Mariana De Niz. I am a postdoctoral fellow at the Institute of Molecular Medicine in Lisbon, Portugal. My work focuses on understanding the biophysics and dynamics of the parasite Trypanosoma brucei (causative of sleeping sickness), in various tissues of mammalian hosts. I am particularly interested in microscopy methods to image host-parasite interactions, and am keen on developing new methods that enable visualising and investigating these interactions. In my PhD and first postdoc, I worked on investigating various stages of the malaria-causative parasite Plasmodium. I was particularly interested in understanding parasite tropism and mechanisms of sequestration during Plasmodium blood stages, and host cell organelle manipulation during Plasmodium liver stage development.
On-demand spatiotemporal programming of collective cell migration via bioelectric stimulation
Antigenic variation by switching inter-chromosomal interactions with an RNA splicing locus in trypanosomes
Coupled active systems encode emergent behavioral dynamics of the unicellular predator Lacrymaria olor
Fully Unsupervised Probabilistic Noise2Void
Rab11A regulates the constitutive secretory pathway during Toxoplasma gondii invasion of host cells and parasite replication
BIAFLOWS: A collaborative framework to benchmark bioimage analysis workflows
Variant antigen diversity in Trypanosoma vivax is not driven by recombination
Deep Learning-Based Point-Scanning Super-Resolution Imaging
CLIJ: GPU-accelerated image processing for everyone
Quantitative intravital imaging of Plasmodium falciparum sporozoites: A novel platform to test malaria intervention strategies