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Systematic analysis of protein targets associated with adverse events of drugs from clinical trials and post-marketing reports

Ines A. Smit, Avid M. Afzal, Chad H. G. Allen, et al.

AND

Toward in vivo-relevant hERG safety assessment and mitigation strategies based on relationships between non-equilibrium blocker binding, three-dimensional channel-blocker interactions, dynamic occupancy, dynamic exposure, and cellular arrhythmia

Hongbin Wan, Gianluca Selvaggio, Robert A. Pearlstein

Discussion

Epithelial Tissues as Active Solids: From Nonlinear Contraction Pulses to Rupture Resistance

Shahaf Armon, Matthew S. Bull, Avraham Moriel, et al.

Discussion

Miniaturized Devices for Bioluminescence Imaging in Freely Behaving Animals

Dmitrijs Celinskis, Nina Friedman, Mikhail Koksharov, et al.

Discussion

Lineage recording reveals dynamics of cerebral organoid regionalization

Zhisong He, Tobias Gerber, Ashley Maynard, et al.

Discussion

20 years of African Neuroscience: Waking a sleeping giant

MB Maina, U Ahmad, HA Ibrahim, et al.

BAcTrace a new tool for retrograde tracing of neuronal circuits

Sebastian Cachero, Marina Gkantia, Alexander S. Bates, et al.

Breaking the next Cryo-EM resolution barrier – Atomic resolution determination of proteins!

Ka Man Yip, Niels Fischer, Elham Paknia, et al.

Discussion

Glycocalyx-mediated Cell Adhesion and Migration

Samuel Schmidt, Bettina Weigelin, Joost te Riet, et al.

Discussion

Physical constraints on early blastomere packings

James Giammona, Otger Campàs

Structure of the complete, membrane-assembled COPII coat reveals a complex interaction network

Joshua Hutchings, Viktoriya G. Stancheva, Nick R. Brown, et al.

A hydraulic instability drives the cell death decision in the nematode germline

N. T. Chartier, A. Mukherjee, J. Pfanzelter, et al.

Discussion