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Induction of cortical Par complex polarity by designed proteins causes cytoskeletal symmetry breaking in unpolarized mammalian cells

Joseph L. Watson, Ariel J. Ben-Sasson, Alice Bittleston, et al.

Selected by 17 May 2022

Ines Jmel-Boyer

Cell Biology

Selective inhibitors of JAK1 targeting a subtype-restricted allosteric cysteine

Madeline E. Kavanagh, Benjamin D. Horning, Roli Khattri, et al.

Selected by 13 March 2022

Zhang-He Goh

Pharmacology and Toxicology

The roles of distinct Ca2+ signaling mediated by Piezo and inositol triphosphate receptor (IP3R) in the remodeling of E-cadherin during cell dissemination

Alejandra J.H. Cabrera, Barry M. Gumbiner, Young V. Kwon

Selected by 16 February 2022

Holly Smith

Cancer Biology

Bacterial filamentation is an in vivo mechanism for cell-to-cell spreading

Tuan D Tran, Munira Aman Ali, Davin Lee, et al.

Selected by 30 January 2022

Angika Basant

Pathology

Cephalopod Retinal Development Shows Vertebrate-like Mechanisms of Neurogenesis

Francesca Napoli, Christina M. Daly, Stephanie Neal, et al.

Selected by 06 December 2021

Niveda Udaykumar

Developmental Biology

Long-range migration of centrioles to the apical surface of the olfactory epithelium

Kaitlin Ching, Jennifer T. Wang, Tim Stearns

Selected by 03 November 2021

Mafalda Pimentel

Cell Biology

CHD8 regulates gut epithelial cell function and affects autism-related behaviours through the gut-brain axis

Ipsita Chatterjee, Dimitry Getselter, Nasreen Ghaneem, et al.

Selected by 03 November 2021

Nándor Lipták

Animal Behavior and Cognition

Epicardial HDAC3 promotes myocardial growth through a novel microRNA pathway

Jihyun Jang, Guang Song, Qinshan Li, et al.

Selected by 14 October 2021

Anna Meier

Developmental Biology

Origin, specification and differentiation of a rare supporting-like lineage in the developing mouse gonad

Chloé Mayère, Violaine Regard, Aitana Perea-Gomez, et al.

Selected by 29 September 2021

Martin Estermann

Developmental Biology

Rapid redistribution and extensive binding of NANOG and GATA6 at shared regulatory elements underlie specification of divergent cell fates

Joyce J. Thompson, Daniel J. Lee, Apratim Mitra, et al.

Selected by 16 September 2021

María Mariner-Faulí

Genomics

Three-axis classification of mouse lung mesenchymal cells reveals two populations of myofibroblasts

Odemaris Narvaez del Pilar, Jichao Chen

Selected by 08 September 2021

Sagar Varankar

Cell Biology

epithelial-mesenchymal plasticity determines estrogen receptor positive (ER+) breast cancer dormancy and reacquisition of an epithelial state drives awakening

Patrick Aouad, Yueyun Zhang, Céline Stibolt, et al.

Selected by 06 September 2021

Sagar Varankar

Cancer Biology