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The force loading rate drives cell mechanosensing through both reinforcement and fluidization

Ion Andreu, Bryan Falcones, Sebastian Hurst, et al.

Selected by 20 March 2021

Jessica L. Teo

Biophysics

Collagen polarization provides a structural memory for the elongation of epithelial anlage

Hiroko Katsuno-Kambe, Jessica L. Teo, Robert J. Ju, et al.

Selected by 19 March 2021

Ilaria Di Meglio

Cell Biology

The Single-Celled Ancestors of Animals: A History of Hypotheses

Thibaut Brunet , Nicole King

Selected by 05 January 2021

Hiral Shah, Dey Lab

Evolutionary Biology

Imaging transmembrane dynamics of biomolecules at live cell plasma membranes using quenchers in extracellular environment

Wenqing Hou, Dongfei Ma, Xiaolong He, et al.

Selected by 02 December 2020

Mariana De Niz

Cell Biology

The human brain vasculature shows a distinct expression pattern of SARS-CoV-2 entry factors

Moheb Ghobrial, Jason Charish, Shigeki Takada, et al.

Selected by 21 October 2020

Kristina Kuhbandner

Neuroscience

Intestinal infection results in impaired lung innate immunity to secondary respiratory infection

Shubhanshi Trivedi, Allie H. Grossmann, Owen Jensen, et al.

Selected by 30 September 2020

Josie Gibson

Immunology

Antifungal effects of PC945, a novel inhaled triazole, on Candida albicans-infected immunocompromised mice

Yuki Nishimoto, Kazuhiro Ito, Genki Kimura, et al.

Selected by 23 September 2020

Zhang-He Goh

Pharmacology and Toxicology

A Transcriptional Switch Governing Fibroblast Plasticity Underlies Reversibility of Chronic Heart Disease

Michael Alexanian, Pawel F. Przytycki, Rudi Micheletti, et al.

Selected by 11 August 2020

Osvaldo Contreras, Alexander Ward

Cell Biology

Large-scale curvature sensing by epithelial monolayers depends on active cell mechanics and nuclear mechanoadaptation

Marine Luciano, Shi-Lei Xue, Winnok H. De Vos, et al.

Selected by 10 August 2020

Grace Lim, Ilaria Di Meglio

Biophysics

A High Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute lung Injury during the COVID-19 pandemic

Maria Alimova, Eriene-Heidi Sidhom, Abhigyan Satyam, et al.

AND

Anti-SARS-CoV-2 IgG from severely ill COVID-19 patients promotes macrophage hyper-inflammatory responses

Willianne Hoepel, Hung-Jen Chen, Sona Allahverdiyeva, et al.

Selected by 31 July 2020

Yen-Chung Chen

Immunology

Electron Transfer from Cytochrome P450 Reductase to Cytochrome P450: Towards a Structural and Dynamic Understanding

Goutam Mukherjee, Prajwal P. Nandekar, Rebecca C. Wade

Selected by 27 July 2020

Zhang-He Goh

Pharmacology and Toxicology

Transcription repressor protein ZBTB25 interacts with HDAC1 in macrophages infected with Mycobacterium tuberculosis, and its inhibition leads to autophagy and killing of the intracellular pathogen

Aravind Madhavan, K B Arun, Akhil Raj Pushparajan, et al.

AND

Tamoxifen reduces inflammatory infiltration of neutrophils in the airways

Agustín Mansilla, Jaime Soto, Claudio Henríquez, et al.

Selected by 25 July 2020

Zhang-He Goh, Josie Gibson

Pharmacology and Toxicology