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Single-cell RNA-sequencing reveals profibrotic roles of distinct epithelial and mesenchymal lineages in pulmonary fibrosis

Arun C. Habermann, Austin J. Gutierrez, Linh T. Bui, et al.

AND

Single Cell RNA-seq reveals ectopic and aberrant lung resident cell populations in Idiopathic Pulmonary Fibrosis

Taylor S. Adams, Jonas C. Schupp, Sergio Poli, et al.

Nanopore-based genome assembly and the evolutionary genomics of basmati rice

Jae Young Choi, Zoe N. Lye, Simon C. Groen, et al.

Negative frequency-dependent selection maintains coexisting genotypes during fluctuating selection

Caroline B. Turner, Sean W. Buskirk, Katrina B. Harris, et al.

The Wnt pathway scaffold protein Axin promotes signaling specificity by suppressing competing kinase reactions

Maire Gavagan, Elizabeth Speltz, Jesse Zalatan

Discussion

Correction of Niemann-Pick type C1 disease with the histone deacetylase inhibitor valproic acid

Kanagaraj Subramanian, Darren M Hutt, Vijay Gupta, et al.

Delineating the rules for structural adaptation of membrane-associated proteins to evolutionary changes in membrane lipidome

Maria Makarova, Maria Peter, Gabor Balogh, et al.

Discussion

A novel weight lifting task for investigating effort and persistence in rats

Blake Porter, Kristin L. Hillman

Discussion

Direct Arp2/3-vinculin binding is essential for cell spreading, but only on compliant substrates and in 3D

Tadamoto Isogai, Kevin M. Dean, Philippe Roudot, et al.

Cross-species transcriptomic and epigenomic analysis reveals key regulators of injury response and neuronal regeneration in vertebrate retinas

Thanh Hoang, Jie Wang, Patrick Boyd, et al.

Discussion

Single-cell gene regulatory network analysis reveals new melanoma cell states and transition trajectories during phenotype switching

Jasper Wouters, Zeynep Kalender-Atak, Liesbeth Minnoye, et al.

Discussion

A conserved ATG2-GABARAP interaction is critical for phagophore closure

Mihaela Bozic, Luuk van den Bekerom, Beth A. Milne, et al.

Discussion

A single-cell transcriptomics CRISPR-activation screen identifies new epigenetic regulators of zygotic genome activation

Celia Alda-Catalinas, Danila Bredikhin, Irene Hernando-Herraez, et al.