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A single-cell transcriptomics CRISPR-activation screen identifies new epigenetic regulators of zygotic genome activation

Celia Alda-Catalinas, Danila Bredikhin, Irene Hernando-Herraez, et al.

Selected by 11 September 2019

Sergio Menchero

Developmental Biology

Hypoxia induces transcriptional and translational downregulation of the type I interferon (IFN) pathway in multiple cancer cell types

Ana Miar, Esther Arnaiz, Esther Bridges, et al.

Selected by 25 August 2019

Jonny Coates

Cancer Biology

Gene regulatory network inference and analysis of multidrug-resistant Pseudomonas aeruginosa

Fernando Medeiros Filho, Ana Paula Barbosa do Nascimento, Marcelo Trindade dos Santos, et al.

Selected by 19 July 2019

Euan McDonnell

Bioinformatics

Elucidating the molecular determinants of Aβ aggregation with deep mutational scanning

Vanessa E Gray, Katherine Sitko, Floriane Z. Ngako Kameni, et al.

Selected by 18 July 2019

Suzanne McDermott

Molecular Biology

Regional heterogeneity of early GABAergic interneuron excitation in vivo

Yasunobu Murata, Matthew T Colonnese

Selected by 17 July 2019

Craig Bertram

Neuroscience

Pulmonary natural killer cells control neutrophil intravascular motility and response to acute inflammation

J. Secklehner, K. De Filippo, J. B. G. Mackey, et al.

Selected by 02 July 2019

Jonny Coates

Immunology

Rapid discovery of synthetic DNA sequences to rewrite endogenous T cell circuits

Theodore L. Roth, P. Jonathan Li, Jasper F. Nies, et al.

Selected by 18 June 2019

Pavithran Ravindran

Bioengineering

Liver-Chip: Reproducing Human and Cross-Species Toxicities

Kyung-Jin Jang, Monicah A. Otieno, Janey Ronxhi, et al.

Selected by 07 June 2019

Zhang-He Goh

Pharmacology and Toxicology

High-throughput mapping of mesoscale connectomes in individual mice

Longwen Huang, Justus M Kebschull, Daniel Furth, et al.

Selected by 05 June 2019

Dena Goldblatt

Neuroscience

Tousled-like kinase activity is required for transcriptional silencing and suppression of innate immune signaling

Sandra Segura-Bayona, Marina Villamor-Payà, Camille Stephan-Otto Attolini, et al.

Selected by 06 May 2019

Yasmin Lau

Molecular Biology

Human DNA-PK activates a STING-independent DNA sensing pathway

Katelyn Burleigh, Joanna H. Maltbaek, Stephanie Cambier, et al.

Selected by 19 April 2019

Connor Rosen

Immunology

Evolution-guided design of super-restrictor antiviral proteins reveals a breadth-versus-specificity tradeoff

Rossana S Colon-Thillet, Emily S Hsieh, Laura Graf, et al.

Selected by 13 March 2019

Connor Rosen

Immunology