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The histone chaperone FACT induces Cas9 multi-turnover behavior and modifies genome manipulation in human cells

Alan S. Wang, Leo Chen, R. Alex Wu, et al.

Selected by 20 August 2019

Nicola Stevenson

Molecular Biology

Arl13b regulates Sonic Hedgehog signaling from outside primary cilia

Eduardo D. Gigante, Megan R. Taylor, Anna A. Ivanova, et al.

Selected by 15 August 2019

Alex Eve

Developmental Biology

Identification of a master regulator of differentiation in Toxoplasma

Benjamin S. Waldman, Dominic Schwarz, Marc H. Wadsworth II, et al.

Selected by 10 July 2019

Juan Quintana

Developmental Biology

CLADES: a programmable sequence of reporters for lineage analysis

Jorge Garcia-Marques, Ching-Po Yang, Isabel Espinosa-Medina, et al.

Selected by 07 July 2019

Ying-Tsen Tung

Developmental Biology

Rapid discovery of synthetic DNA sequences to rewrite endogenous T cell circuits

Theodore L. Roth, P. Jonathan Li, Jasper F. Nies, et al.

Selected by 18 June 2019

Pavithran Ravindran

Bioengineering

Endogenous CRISPR arrays for scalable whole organism lineage tracing

James Cotterell, James Sharpe

Selected by 27 February 2019

Irepan Salvador-Martinez

Bioinformatics

Conditional Guide RNAs: Programmable Conditional Regulation of CRISPR/Cas Function in Bacteria via Dynamic RNA Nanotechnology

Mikhail H. Hanewich-Hollatz, Zhewei Chen, Jining Huang, et al.

Selected by 18 February 2019

Pavithran Ravindran

Bioengineering

Inactive USP14 and inactive UCHL5 cause accumulation of distinct ubiquitinated proteins in mammalian cells

Jayashree Chadchankar, Victoria Korboukh, Peter Doig, et al.

Selected by 31 January 2019

Mila Basic

Molecular Biology

Reconstruction of the global neural crest gene regulatory network in vivo

Ruth M Williams, Ivan Candido-Ferreira, Emmanouela Repapi, et al.

Selected by 28 January 2019

Hannah Brunsdon

Genomics

Phase transition and amyloid formation by a viral protein as an additional molecular mechanism of virus-induced cell toxicity

Edoardo Salladini, Claire Debarnot, Vincent Delauzun, et al.

Selected by 11 January 2019

Tessa Sinnige

Biophysics

A pharmacokinetic-pharmacodynamic assessment of the hepatic and bone-marrow toxicities of the new trypanoside fexinidazole

James Andrew Watson, Nathalie Strub-Wourgraft, Antoine Tarral, et al.

Selected by 18 December 2018

Zhang-He Goh

Pharmacology and Toxicology

Evidence for an Integrated gene Repression Mechanism based on mRNA Isoform Toggling in Human Cells

Ina Hollerer, Juliet C Barker, Victoria Jorgensen, et al.

Selected by 30 October 2018

Clarice Hong

Genetics
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