The nucleocytosolic O-fucosyltransferase Spindly affects protein expression and virulence in Toxoplasma gondii
Selected by
05 October 2020
Jennifer Ann Black
Intestinal infection results in impaired lung innate immunity to secondary respiratory infection
Selected by
30 September 2020
Josie Gibson
Antifungal effects of PC945, a novel inhaled triazole, on Candida albicans-infected immunocompromised mice
Selected by
23 September 2020
Zhang-He Goh
SARS-CoV-2 infects brain choroid plexus and disrupts the blood-CSF-barrier
Selected by
18 September 2020
Theresa Pohlkamp
Amoeba predation of Cryptococcus neoformans results in pleiotropic changes to traits associated with virulence
Selected by
02 September 2020
Josie Gibson
Targeting of Mammalian Glycans Enhances Phage Predation in the Gastrointestinal Tract
Selected by
25 August 2020
Connor Rosen
Passage of transmissible cancers in the Tasmanian devil is due to a dominant, shared peptide motif and a limited repertoire of MHC-I allotypes
Selected by
12 August 2020
Jennifer Ann Black
High-content Imaging-based Pooled CRISPR Screens in Mammalian Cells
AND
Image-based pooled whole genome CRISPR screening for Parkin and TFEB subcellular localization
Selected by
10 August 2020
Kirsty Ferguson
A High Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury during the COVID-19 pandemic
AND
Anti-SARS-CoV-2 IgG from severely ill COVID-19 patients promotes macrophage hyper-inflammatory responses
Selected by
31 July 2020
Yen-Chung Chen
Severe immunodeficiency in mice lacking DNA repair factors XLF and Mri
Selected by
27 July 2020
Jennifer Ann Black
Galectin-8 senses phagosomal damage and recruits selective autophagy adapter TAX1BP1 to control Mycobacterium tuberculosis infection in macrophages
Selected by
25 July 2020
Josie Gibson, Zhang-He Goh
Transcription repressor protein ZBTB25 interacts with HDAC1 in macrophages infected with Mycobacterium tuberculosis, and its inhibition leads to autophagy and killing of the intracellular pathogen
AND
Tamoxifen reduces inflammatory infiltration of neutrophils in the airways
Selected by
25 July 2020
Zhang-He Goh, Josie Gibson