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The nucleocytosolic O-fucosyltransferase Spindly affects protein expression and virulence in Toxoplasma gondii

Giulia Bandini, Carolina Agop-Nersesian, Hanke van der Wel, et al.

Selected by 05 October 2020

Jennifer Ann Black

Microbiology

Intestinal infection results in impaired lung innate immunity to secondary respiratory infection

Shubhanshi Trivedi, Allie H. Grossmann, Owen Jensen, et al.

Selected by 30 September 2020

Josie Gibson

Immunology

Antifungal effects of PC945, a novel inhaled triazole, on Candida albicans-infected immunocompromised mice

Yuki Nishimoto, Kazuhiro Ito, Genki Kimura, et al.

Selected by 23 September 2020

Zhang-He Goh

Pharmacology and Toxicology

SARS-CoV-2 infects brain choroid plexus and disrupts the blood-CSF-barrier

Laura Pellegrini, Anna Albecka, Donna L. Mallery, et al.

Selected by 18 September 2020

Theresa Pohlkamp

Cell Biology

Amoeba predation of Cryptococcus neoformans results in pleiotropic changes to traits associated with virulence

Man Shun Fu, Livia C. Liporagi-Lopes, Samuel R. dos Santos Júnior, et al.

Selected by 02 September 2020

Josie Gibson

Microbiology

Targeting of Mammalian Glycans Enhances Phage Predation in the Gastrointestinal Tract

Sabrina I. Green, Carmen Gu Liu, Xue Yu, et al.

Selected by 25 August 2020

Connor Rosen

Microbiology

Passage of transmissible cancers in the Tasmanian devil is due to a dominant, shared peptide motif and a limited repertoire of MHC-I allotypes

A Gastaldello, SH Ramarathinam, A Bailey, et al.

Selected by 12 August 2020

Jennifer Ann Black

Immunology

High-content Imaging-based Pooled CRISPR Screens in Mammalian Cells

Xiaowei Yan, Nico Stuurman, Susana A. Ribeiro, et al.

AND

Image-based pooled whole genome CRISPR screening for Parkin and TFEB subcellular localization

Gil Kanfer, Shireen A. Sarraf, Yaakov Maman, et al.

Selected by 10 August 2020

Kirsty Ferguson

Cell Biology

A High Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury during the COVID-19 pandemic

Maria Alimova, Eriene-Heidi Sidhom, Abhigyan Satyam, et al.

AND

Anti-SARS-CoV-2 IgG from severely ill COVID-19 patients promotes macrophage hyper-inflammatory responses

Willianne Hoepel, Hung-Jen Chen, Sona Allahverdiyeva, et al.

Selected by 31 July 2020

Yen-Chung Chen

Immunology

Severe immunodeficiency in mice lacking DNA repair factors XLF and Mri

Sergio Castañeda-Zegarra, Qindong Zhang, Amin Alirezaylavasani, et al.

Selected by 27 July 2020

Jennifer Ann Black

Immunology

Galectin-8 senses phagosomal damage and recruits selective autophagy adapter TAX1BP1 to control Mycobacterium tuberculosis infection in macrophages

Samantha L. Bell, Kayla L. Lopez, Jeffery S. Cox, et al.

Selected by 25 July 2020

Josie Gibson, Zhang-He Goh

Microbiology

Transcription repressor protein ZBTB25 interacts with HDAC1 in macrophages infected with Mycobacterium tuberculosis, and its inhibition leads to autophagy and killing of the intracellular pathogen

Aravind Madhavan, K B Arun, Akhil Raj Pushparajan, et al.

AND

Tamoxifen reduces inflammatory infiltration of neutrophils in the airways

Agustín Mansilla, Jaime Soto, Claudio Henríquez, et al.

Selected by 25 July 2020

Zhang-He Goh, Josie Gibson

Pharmacology and Toxicology
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