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Small leucine-rich proteoglycans inhibit CNS regeneration by modifying the structural and mechanical properties of the lesion environment

Julia Kolb, Nora John, Kyoohyun Kim, et al.

Reversible bacteriophage resistance by shedding the bacterial cell wall

Veronique Ongenae, Adam Sidi Mabrouk, Marjolein Crooijmans, et al.

Astrocyte plasticity ensures continued endfoot coverage of cerebral blood vessels and integrity of the blood brain barrier, with plasticity declining with normal aging

William A. Mills III, Shan Jiang, Joelle Martin, et al.

Discussion

CSPα reduces aggregates and rescues striatal dopamine release in αsynuclein transgenic mice

L Caló, E Hidari, M Wegrzynowicz, et al.

Systematic analysis of protein targets associated with adverse events of drugs from clinical trials and post-marketing reports

Ines A. Smit, Avid M. Afzal, Chad H. G. Allen, et al.

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Toward in vivo-relevant hERG safety assessment and mitigation strategies based on relationships between non-equilibrium blocker binding, three-dimensional channel-blocker interactions, dynamic occupancy, dynamic exposure, and cellular arrhythmia

Hongbin Wan, Gianluca Selvaggio, Robert A. Pearlstein

Discussion

Orally Bioavailable Endochin-like Quinolone Carbonate Ester Prodrug Reduces Toxoplasma gondii Brain Cysts

J. Stone Doggett, Tracey Schultz, Alyssa J. Miller, et al.

Discussion

Effective buprenorphine use and tapering strategies: Endorsements and insights by people in recovery from opioid use disorder on a Reddit forum

Rachel L Graves, Abeed Sarker, Mohammed Ali Al-Garadi, et al.

Discussion

Hepatocyte-specific deletion of Pparα promotes NASH in the context of obesity

Marion Regnier, Arnaud Polizzi, Sarra Smati, et al.

Applications of Machine Learning in Decision Analysis for Dose Management for Dofetilide

Andrew E Levy, Minakshi Biswas, Rachel Weber, et al.

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Optimal Scheduling of Bevacizumab and Pemetrexed/Cisplatin Dosing in Non-Small Cell Lung Cancer

Benjamin Schneider, Arnaud Boyer, Joseph Ciccolini, et al.

Discussion

Development and validation of serological markers for detecting recent exposure to Plasmodium vivax infection

Rhea Jessica Longley, Michael T White, Eizo Takashima, et al.

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Antimalarial drug mefloquine kills both trophozoite and cyst stages of Entamoeba

Conall Sauvey, Gretchen Ehrenkaufer, Anjan Debnath, et al.

Discussion

Ecological analyses of mycobacteria in showerhead biofilms and their relevance to human health

Matthew Gebert, Manuel Delgado-Baquerizo, Angela Oliverio, et al.

Discussion