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Generalized Biomolecular Modeling and Design with RoseTTAFold All-Atom

Rohith Krishna, Jue Wang, Woody Ahern, et al.



Selected by Saanjbati Adhikari

Inference of drug off-target effects on cellular signaling using Interactome-Based Deep Learning

Nikolaos Meimetis, Douglas A. Lauffenburger, Avlant Nilsson



Selected by Benjamin Dominik Maier

Tardigrades dramatically upregulate DNA repair pathway genes in response to ionizing radiation

Courtney M. Clark-Hachtel, Jonathan D. Hibshman, Tristan De Buysscher, et al.



Selected by Isabella Cisneros

Mechano-dependent sorbitol accumulation supports biomolecular condensate

Stephanie Torrino, William M Oldham, Andrés R Tejedor, et al.



Selected by Teodora Piskova

Mitochondrial citrate carrier SLC25A1 is a dosage-dependent regulator of metabolic reprogramming and morphogenesis in the developing heart

Chiemela Ohanele, Jessica N. Peoples, Anja Karlstaedt, et al.



Selected by Chee Kiang Ewe, Preethi Krishnaraj

Preprint Peer Review – biochemistry Course at UFRJ, Brazil

Communication of scientific knowledge has changed dramatically in recent decades and the public perception of scientific discoveries depends on the peer review process of articles published in scientific journals. Preprints are key vehicles for the dissemination of scientific discoveries, but they are still not properly recognized by the scientific community since peer review is very limited. On the other hand, peer review is very heterogeneous and a fundamental aspect to improve it is to train young scientists on how to think critically and how to evaluate scientific knowledge in a professional way. Thus, this course aims to: i) train students on how to perform peer review of scientific manuscripts in a professional manner; ii) develop students' critical thinking; iii) contribute to the appreciation of preprints as important vehicles for the dissemination of scientific knowledge without restrictions; iv) contribute to the development of students' curricula, as their opinions will be published and indexed on the preLights platform. The evaluations will be based on qualitative analyses of the oral presentations of preprints in the field of biochemistry deposited in the bioRxiv server, of the critical reports written by the students, as well as of the participation of the students during the preprints discussions.

 



List by Marcus Oliveira

Multifunctional fluorophores for live-cell imaging and affinity capture of proteins

Pratik Kumar, Jason D. Vevea, Edwin R. Chapman, et al.



Selected by Zhang-He Goh

Oxycodone decreases anxiety-like behavior in the elevated plus-maze test in male and female rats

Adriaan W. Bruijnzeel, Azin Behnood-Rod, Wendi Malphurs, et al.



Selected by Nándor Lipták

Circularly permuted LOV domain as an engineering module for optogenetic tools

Lequn Geng, Jiaqi Shen, Wenjing Wang



Selected by Soni Mohapatra

Clathrin adaptors mediate two sequential pathways of intra-Golgi recycling

Jason C. Casler, Adam H. Krahn, Areti Pantazopoulou, et al.



Selected by Jennifer Ann Black

Ultrasensitive RNA biosensors for SARS-CoV-2 detection in a simple color and luminescence assay

Anirudh Chakravarthy, Anirudh K N, Geen George, et al.



Selected by Angika Basant

The nucleocytosolic O-fucosyltransferase Spindly affects protein expression and virulence in Toxoplasma gondii

Giulia Bandini, Carolina Agop-Nersesian, Hanke van der Wel, et al.



Selected by Jennifer Ann Black

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