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The Wnt pathway scaffold protein Axin promotes signaling specificity by suppressing competing kinase reactions

Maire Gavagan, Elizabeth Speltz, Jesse Zalatan

Selected by Yasmin Lau

Direct Arp2/3-vinculin binding is essential for cell spreading, but only on compliant substrates and in 3D

Tadamoto Isogai, Kevin M. Dean, Philippe Roudot, et al.

Selected by Ankita Jha

Single-cell gene regulatory network analysis reveals new melanoma cell states and transition trajectories during phenotype switching

Jasper Wouters, Zeynep Kalender-Atak, Liesbeth Minnoye, et al.

Selected by Hannah Brunsdon

Hypoxia induces transcriptional and translational downregulation of the type I interferon (IFN) pathway in multiple cancer cell types

Ana Miar, Esther Arnaiz, Esther Bridges, et al.

Selected by Jonny Coates

Single molecule mechanics resolves the earliest events in force generation by cardiac myosin

Michael S. Woody, Donald A. Winkelmann, Marco Capitanio, et al.

Selected by Alyson Smith

Metabolism of fatty acids and ketone bodies for glioblastoma growth: Implications for Ketogenic Diet Therapy

Jantzen Sperry, Janel E. Le Belle, Michael C. Condro, et al.

Selected by Pablo Ranea Robles

Gene regulatory network inference and analysis of multidrug-resistant Pseudomonas aeruginosa

Fernando Medeiros Filho, Ana Paula Barbosa do Nascimento, Marcelo Trindade dos Santos, et al.

Selected by Euan McDonnell

Rab11b-mediated integrin recycling promotes brain metastatic adaptation and outgrowth

Erin N. Howe, Miranda D. Burnette, Melanie E. Justice, et al.

Selected by Beverley Wilson

Negative Regulation of Autophagy by UBA6-BIRC6–Mediated Ubiquitination of LC3

Rui Jia, Juan S. Bonifacino

Selected by Sandra Malmgren Hill

Contractile acto-myosin network on nuclear envelope remnants positions human chromosomes for mitosis

Alexander JR Booth, Zuojun Yue, John K Eykelenboom, et al.

Selected by Alyson Smith

Rapid discovery of synthetic DNA sequences to rewrite endogenous T cell circuits

Theodore L. Roth, P. Jonathan Li, Jasper F. Nies, et al.

Selected by Pavithran Ravindran

Adipocyte vesicles: ‘all-in-one’ packages that stimulate tumor mitochondrial metabolism and dynamics

Emily Clement, Ikrame Lazar, Camille Attané, et al.