You searched for crispr

Drug mechanism-of-action discovery through the integration of pharmacological and crispr screens

Emanuel Gonçalves, Aldo Segura-Cabrera, Clare Pacini, et al.

Selected by Georgina Sava

Trophectoderm Potency is Retained Exclusively in Human Naïve Cells

Ge Guo, Giuliano Giuseppe Stirparo, Stanley Strawbridge, et al.

Selected by Sergio Menchero

Hedgehog signaling is required for endomesodermal patterning and germ cell development in Nematostella vectensis

Cheng-Yi Chen, Sean A. McKinney, Lacey R. Ellington, et al.

Selected by Paul Gerald L. Sanchez and Stefano Vianello

DRP1-mediated regulation of mitochondrial dynamics determines the apoptotic response upon embryonic differentiation

Barbara Pernaute, Juan Miguel Sánchez Nieto, Salvador Pérez-Montero, et al.

Selected by Katarzyna Kuzmicz-Kowalska

Programmable crispr interference for gene silencing using Cas13a in mosquitoes

Aditi Kulkarni, Wanqin Yu, Alex Moon, et al.

Selected by Yasmin Lau

Architectural RNA is required for heterochromatin organization

Jitendra Thakur, He Fang, Trizia Llagas, et al.

Selected by Ramona Jühlen

EXO70A2 is critical for the exocyst complex function in Arabidopsis pollen

Vedrana Marković, Fatima Cvrčková, Martin Potocký, et al.

Selected by Chandra Shekhar Misra

GeneWalk identifies relevant gene functions for a biological context using network representation learning

Robert Ietswaart, Benjamin M. Gyori, John A. Bachman, et al.

Selected by Ramona Jühlen

Direct Arp2/3-vinculin binding is essential for cell spreading, but only on compliant substrates and in 3D

Tadamoto Isogai, Kevin M. Dean, Philippe Roudot, et al.

Selected by Ankita Jha

A conserved ATG2-GABARAP interaction is critical for phagophore closure

Mihaela Bozic, Luuk van den Bekerom, Beth A. Milne, et al.

Selected by Mila Basic

A single-cell transcriptomics crispr-activation screen identifies new epigenetic regulators of zygotic genome activation

Celia Alda-Catalinas, Danila Bredikhin, Irene Hernando-Herraez, et al.