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The properties of α-synuclein secondary nuclei are dominated by the solution conditions rather than the seed fibril strain

Alessia Peduzzo, Sara Linse, Alexander K. Buell

Direct Arp2/3-vinculin binding is essential for cell spreading, but only on compliant substrates and in 3D

Tadamoto Isogai, Kevin M. Dean, Philippe Roudot, et al.

N-cadherin stabilises neural identity by dampening anti-neural signals

K Punovuori, RP Migueles, M Malaguti, et al.

A modification to the life cycle of the parasite Trypanosoma brucei

Sarah Schuster, Ines Subota, Jaime Lisack, et al.

Discussion

Estimates of genetic load in small populations suggest extensive purging of deleterious alleles

Tom van der Valk, Marc de Manuel, Tomas Marques-Bonet, et al.

Higher Temperatures Generically Favor Slower-Growing Bacterial Species in Multispecies Communities

Simon Lax, Clare I. Abreu, Jeff Gore

Discussion

Intestinal delta-6-desaturase activity determines host range for Toxoplasma sexual reproduction

Bruno Martorelli Di Genova, Sarah K. Wilson, J.P. Dubey, et al.

A large-scale resource for tissue-specific CRISPR mutagenesis in Drosophila

Fillip Port, Claudia Strein, Mona Stricker, et al.

In vivo glucose imaging in multiple model organisms with an engineered single-wavelength sensor

Jacob P. Keller, Jonathan S. Marvin, Haluk Lacin, et al.

Hepatocyte-specific deletion of Pparα promotes NASH in the context of obesity

Marion Regnier, Arnaud Polizzi, Sarra Smati, et al.

Planar differential growth rates determine the position of folds in complex epithelia

Melda Tozluoğlu, Maria Duda, Natalie J Kirkland, et al.

AND

Buckling of epithelium growing under spherical confinement

Anastasiya Trushko, Ilaria Di Meglio, Aziza Merzouki, et al.

On-site ribosome remodeling by locally synthesized ribosomal proteins in axons

Toshiaki Shigeoka, Max Koppers, Hovy Ho-Wai Wong, et al.

Discussion