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Selective inhibitors of JAK1 targeting a subtype-restricted allosteric cysteine

Madeline E. Kavanagh, Benjamin D. Horning, Roli Khattri, et al.

Selected by 13 March 2022

Zhang-He Goh

Pharmacology and Toxicology

ATM-dependent formation of a novel chromatin compartment regulates the Response to DNA Double Strand Breaks and the biogenesis of translocations

Coline Arnould, Vincent Rocher, Aldo S. Bader, et al.

Selected by 17 February 2022

Jennifer Ann Black

Molecular Biology

The roles of distinct Ca2+ signaling mediated by Piezo and inositol triphosphate receptor (IP3R) in the remodeling of E-cadherin during cell dissemination

Alejandra J.H. Cabrera, Barry M. Gumbiner, Young V. Kwon

Selected by 16 February 2022

Holly Smith

Cancer Biology

CDK9 and PP2A regulate the link between RNA polymerase II transcription termination and RNA maturation

Michael Tellier, Justyna Zaborowska, Jonathan Neve, et al.

Selected by 02 November 2021

Isabella Maudlin

Molecular Biology

PLK1 controls centriole distal appendage formation and centrobin removal via independent pathways

Morgan Le Roux-Bourdieu, Daniela Harry, Patrick Meraldi

Selected by 29 September 2021

Mafalda Pimentel

Cell Biology

Self-organized morphogenesis of a human neural tube in vitro by geometric constraints

Eyal Karzbrun, Aimal H. Khankhel, Heitor C. Megale, et al.

Selected by 22 September 2021

Srivatsava Viswanadha

Bioengineering

Nuclear soluble cGAS senses DNA virus infection

Yakun Wu, Kun Song, Wenzhuo Hao, et al.

Selected by 16 September 2021

Roberto Amadio

Immunology

Epithelial-mesenchymal plasticity determines estrogen receptor positive (ER+) breast cancer dormancy and reacquisition of an epithelial state drives awakening

Patrick Aouad, Yueyun Zhang, Céline Stibolt, et al.

Selected by 06 September 2021

Sagar Varankar

Cancer Biology

Cellular chaining influences biofilm formation and structure in Group A Streptococcus

Artur Matysik, Foo Kiong Ho, Alicia Qian Ler Tan, et al.

Selected by 02 September 2021

SCELSE Summer School

Molecular Biology

Astrocyte plasticity ensures continued endfoot coverage of cerebral blood vessels and integrity of the blood brain barrier, with plasticity declining with normal aging

William A. Mills III, Shan Jiang, Joelle Martin, et al.

Selected by 20 July 2021

Ranabir Chakraborty

Neuroscience

The Drosophila anterior-posterior axis is polarized by asymmetric myosin activation

Hélène Doerflinger, Vitaly Zimyanin, Daniel St Johnston

Selected by 09 June 2021

Giuliana Clemente

Developmental Biology

Scaling of cellular proteome with ploidy

Galal Yaha, Paul Menges, Devi Anggraini Ngandiri, et al.

Selected by 31 May 2021

Jennifer Ann Black

Cell Biology