Downstream of gasdermin D cleavage, a Ragulator-Rag-mTORC1 pathway promotes pore formation and pyroptosis
Selected by
Connor Rosen
Genome-wide CRISPRi/a screens in human neurons link lysosomal failure to ferroptosis
Selected by
Berrak Ugur
DMD-based super-resolution structured illumination microscopy visualizes live cell dynamics at high speed and low cost
Selected by
Mariana De Niz
Mitophagy protects beta cells from inflammatory damage in diabetes
Selected by
Giuliana Clemente
Stem-cell niche self-restricts the signaling range via receptor-ligand degradation
Selected by
Nadia Edelsztein
Endoplasmic reticulum (ER) lumenal indicators in Drosophila reveal effects of HSP-related mutations on ER calcium dynamics
Selected by
Mónica Quiñones-Frías
Lysosomal activity regulates Caenorhabditis elegans mitochondrial dynamics through vitamin B12 metabolism
Selected by
Aakriti Jain
Changing and stable chromatin accessibility supports transcriptional overhaul during neural stem cell activation
Selected by
Kirsty Ferguson
ER-Mitochondria Contacts Promote Mitochondrial-Derived Compartment Biogenesis
AND
Mitochondrial-Derived Compartments Facilitate Cellular Adaptation to Amino Acid Stress
Selected by
Berrak Ugur
Quantitative analysis of the ubiquitin-proteasome system under proteolytic and folding stressors
Selected by
Sandra Malmgren Hill
The WD and linker domains of ATG16L1 required for non-canonical autophagy limit lethal influenza A virus infection at epithelial surfaces
Selected by
Kirsty Hooper
ULK complex organization in autophagy by a C-shaped FIP200 N-terminal domain dimer
Selected by
Sandra Malmgren Hill