Foldamers Reveal and Validate Novel Therapeutic Targets Associated with Toxic α-Synuclein Self-Assembly
Selected by
Joanna Zell
Suppression of aggregate and amyloid formation by a novel intrinsically disordered region in metazoan Hsp110 chaperones
Selected by
Utrecht Protein Folding and Assembly
A copper chaperone-mimetic polytherapy for SOD1-associated amyotrophic lateral sclerosis
Selected by
Utrecht Protein Folding and Assembly
Structure of an infectious mammalian prion
Selected by
Jennifer Ann Black
Quantitative analysis of the ubiquitin-proteasome system under proteolytic and folding stressors
Selected by
Sandra Malmgren Hill
HSP110 dependent HSP70 disaggregation machinery mediates prion-like propagation of amyloidogenic proteins in metazoa
Selected by
Tessa Sinnige
Correction of Niemann-Pick type C1 disease with the histone deacetylase inhibitor valproic acid
Selected by
Joanna Cross
Modulation of neuronal resilience during aging by Hsp70/Hsp90/STI1 chaperone system
Selected by
Giuliana Clemente
Spontaneous isomerization of long-lived proteins provides a molecular mechanism for the lysosomal failure observed in Alzheimer’s disease
Selected by
Joanna Cross
Dynamic Aha1 Co-Chaperone Binding to Human Hsp90
Selected by
Reid Alderson
A non-canonical arm of UPRER mediates longevity through ER remodeling and lipophagy.
Selected by
Sandra Franco Iborra
Refolding activity of bacterial Hsp90 in vivo reveals ancient chaperoning function
Selected by
Tessa Sinnige