Search results

Foldamers Reveal and Validate Novel Therapeutic Targets Associated with Toxic α-Synuclein Self-Assembly

Jemil Ahmed, Tessa C. Fitch, Courtney M. Donnelly, et al.

Selected by 05 June 2021

Joanna Zell

Suppression of aggregate and amyloid formation by a novel intrinsically disordered region in metazoan Hsp110 chaperones

Unekwu M. Yakubu, Kevin A. Morano

Selected by 14 April 2021

Utrecht Protein Folding and Assembly

A copper chaperone-mimetic polytherapy for SOD1-associated amyotrophic lateral sclerosis

McAlary L., Shephard V.K., Wright G.S.A., et al.

Selected by 09 April 2021

Utrecht Protein Folding and Assembly

Structure of an infectious mammalian prion

Allison Kraus, Forrest Hoyt, Cindi L. Schwartz, et al.

Selected by 04 March 2021

Jennifer Ann Black

Quantitative analysis of the ubiquitin-proteasome system under proteolytic and folding stressors

Jeremy J. Work, Onn Brandmann

Selected by 27 March 2020

Sandra Malmgren Hill

Discussion

HSP110 dependent HSP70 disaggregation machinery mediates prion-like propagation of amyloidogenic proteins in metazoa

Jessica Tittelmeier, Carl Alexander Sandhof, Heidrun Maja Ries, et al.

Selected by 27 October 2019

Tessa Sinnige

Correction of Niemann-Pick type C1 disease with the histone deacetylase inhibitor valproic acid

Kanagaraj Subramanian, Darren M Hutt, Vijay Gupta, et al.

Selected by 17 September 2019

Joanna Cross

Discussion

Modulation of neuronal resilience during aging by Hsp70/Hsp90/STI1 chaperone system

Rachel Lackie, Abdul Razzaq, Sali M.K. Farhan, et al.

Selected by 12 June 2019

Giuliana Clemente

Spontaneous isomerization of long-lived proteins provides a molecular mechanism for the lysosomal failure observed in Alzheimer’s disease

Tyler R. Lambeth, Dylan L. Riggs, Lance E. Talbert, et al.

Selected by 15 May 2019

Joanna Cross

Discussion

Dynamic Aha1 Co-Chaperone Binding to Human Hsp90

Javier Oroz, Laura J Blair, Markus Zweckstetter

Selected by 19 February 2019

Reid Alderson

A non-canonical arm of UPR^ER mediates longevity through ER remodeling and lipophagy.

Joseph R Daniele, Ryo Higuchi-Sanabria, Vidhya Ramachandran, et al.

Selected by 07 January 2019

Sandra Franco Iborra

Refolding activity of bacterial Hsp90 in vivo reveals ancient chaperoning function

Tania Moran Luengo, Toveann Ahlnas, Anna T. Hoekstra, et al.

Selected by 22 November 2018

Tessa Sinnige

Discussion