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An intestinal sphingolipid promotes neuronal health across generations

Wenyue Wang, Tessa Sherry, Xinran Cheng, et al.

Selected by Chee Kiang Ewe

Real-time visualization of mRNA synthesis during memory formation in live animals

Byung Hun Lee, Jae Youn Shim, Hyungseok C. Moon, et al.

Selected by Kristina Kuhbandner et al.

Ageing-associated myelin dysfunction drives amyloid deposition in mouse models of Alzheimer’s disease

Constanze Depp, Ting Sun, Andrew Octavian Sasmita, et al.

Selected by Kristina Kuhbandner

Tau assemblies enter the cytosol of neurons in a cholesterol sensitive manner

Benjamin J. Tuck, Taxiarchis Katsinelos, Lauren V. C. Miller, et al.

Selected by Emma Wilson

Cytosolic aggregation of mitochondrial proteins disrupts cellular homeostasis by stimulating other proteins aggregation

Urszula Nowicka, Piotr Chroscicki, Karen Stroobants, et al.

Selected by Eric McGregor

Microglia become hypofunctional and release metalloproteases and tau seeds after phagocytosing live neurons with P301S tau aggregates

Jack H. Brelstaff, Matthew Mason, Taxiarchis Katsinelos, et al.

Selected by Kristina Kuhbandner

Structure of an infectious mammalian prion

Allison Kraus, Forrest Hoyt, Cindi L. Schwartz, et al.

Selected by Jennifer Ann Black

Neuronal Enhancers are Hotspots For DNA Single-Strand Break Repair

Wei Wu, Sarah E. Hill, William J. Nathan, et al.

Selected by Giuseppina D'Alessandro, Sree Rama Chaitanya

Functional diversification of Ser-Arg rich protein kinases to control ubiquitin-dependent neurodevelopmental signalling

Francisco Bustos, Anna Segarra-Fas, Gino Nardocci, et al.

Selected by Sree Rama Chaitanya

Genome-wide CRISPRi/a screens in human neurons link lysosomal failure to ferroptosis

Ruilin Tian, Anthony Abarientos, Jason Hong, et al.

Selected by Berrak Ugur

CSPα reduces aggregates and rescues striatal dopamine release in αsynuclein transgenic mice

L Caló, E Hidari, M Wegrzynowicz, et al.

Selected by Kristina Kuhbandner

In situ architecture of neuronal α-Synuclein inclusions

Victoria A. Trinkaus, Irene Riera-Tur, Antonio Martínez-Sánchez, et al.

Selected by Tessa Sinnige