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MCM complexes are barriers that restrict cohesin-mediated loop extrusion

Bart J. H. Dequeker, Hugo B. Brandão, Matthias J. Scherr, et al.

Interstitial spaces are continuous across tissue and organ boundaries in humans

Odise Cenaj, Douglas H. R. Allison, R Imam, et al.

Decoding distinctive features of plasma extracellular vesicles in amyotrophic lateral sclerosis

Laura Pasetto, Stefano Callegaro, Deborah Ferrara, et al.

Human skeletal muscle CD90⁺ fibro-adipogenic progenitors are associated with muscle degeneration in type 2 diabetic patients

Jean Farup, Jesper Just, Frank de Paoli, et al.

Segmentation of the Zebrafish Brain Vasculature from Light Sheet Fluorescence Microscopy Datasets

Elisabeth C. Kugler, Andrik Rampun, Timothy J.A. Chico, et al.

Genome-wide CRISPRi/a screens in human neurons link lysosomal failure to ferroptosis

Ruilin Tian, Anthony Abarientos, Jason Hong, et al.

In situ architecture of neuronal α-Synuclein inclusions

Victoria A. Trinkaus, Irene Riera-Tur, Antonio Martínez-Sánchez, et al.

A Transcriptional Switch Governing Fibroblast Plasticity Underlies Reversibility of Chronic Heart Disease

Michael Alexanian, Pawel F. Przytycki, Rudi Micheletti, et al.

Amyotrophic lateral sclerosis associated mislocalisation of TDP-43 to the cytoplasm causes cortical hyperexcitability and reduced excitatory neurotransmission in the motor cortex

MS Dyer, KE Lewis, AK Walker, et al.

Transcription repressor protein ZBTB25 interacts with HDAC1 in macrophages infected with Mycobacterium tuberculosis, and its inhibition leads to autophagy and killing of the intracellular pathogen

Aravind Madhavan, K B Arun, Akhil Raj Pushparajan, et al.

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Tamoxifen reduces inflammatory infiltration of neutrophils in the airways

Agustín Mansilla, Jaime Soto, Claudio Henríquez, et al.

Surface area-to-volume ratio, not cellular rigidity, determines red blood cell traversal through small capillaries

Arman Namvar, Adam J. Blanch, Matthew W. Dixon, et al.

A lung-on-chip model reveals an essential role for alveolar epithelial cells in controlling bacterial growth during early tuberculosis

Vivek V. Thacker, Neeraj Dhar, Kunal Sharma, et al.