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3D genome organization around nuclear speckles drives mRNA splicing efficiency

Prashant Bhat, Amy Chow, Benjamin Emert, et al.

Selected by Diego Martínez

A patterned human heart tube organoid model generated by pluripotent stem cell self-assembly

Brett Volmert, Ashlin Riggs, Fei Wang, et al.

Selected by Silvia Becca

VAP spatially stabilizes dendritic mitochondria to locally fuel synaptic plasticity

Ojasee Bapat, Tejas Purimetla, Sarah Kruessel, et al.

Selected by Kritika Mehta

ARHGEF18 participates in Endothelial Cell Mechano-sensitivity in Response to Flow

Surya Prakash Rao Batta, Marc Rio, Corentin Lebot, et al.

Selected by Aarren Mannion

Gigaxonin is required for intermediate filament transport

Bhuvanasundar Renganathan, James P Zewe, Yuan Cheng, et al.

Selected by Suganya Sivagurunathan

DOT1L activity affects cell lineage progression in the developing brain by controlling metabolic programs

Bismark Appiah, Camilla L. Fullio, Christiane Haffner, et al.

Selected by Laura Celotto

MPS1 localizes to microtubule-attached kinetochores and actively promotes microtubule release

Daniel Hayward, Emile Roberts, Ulrike Gruneberg

Selected by Saanjbati Adhikari

Sub-lethal apoptotic stress enables mtDNA release during senescence and drives the SASP

James Chapman, Hanna Salmonowicz, Stella Victorelli, et al.

Selected by Roberto Amadio

Pin1-promoted SUMOylation of RNF168 restrains its chromatin accumulation

Anoop Singh Chauhan, Alexander J. Garvin, Mohammed Jamshad, et al.

Selected by Pierre Caron

Induction of cortical Par complex polarity by designed proteins causes cytoskeletal symmetry breaking in unpolarized mammalian cells

Joseph L. Watson, Ariel J. Ben-Sasson, Alice Bittleston, et al.

Selected by Ines Jmel-Boyer

Long read mitochondrial genome sequencing using Cas9-guided adaptor ligation

Amy R. Vandiver, Brittany Pielstick, Timothy Gilpatrick, et al.

Selected by Nate Mullin

Dissecting β-Cardiac Myosin and Cardiac Myosin-Binding Protein C Interactions using a Nanosurf Assay

Anja M. Touma, Wanjian Tang, David V. Rasicci, et al.

Selected by Neha Nandwani