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The loss of DNA polymerase epsilon accessory subunits POLE3-POLE4 leads to BRCA1-independent PARP inhibitor sensitivity

Hasan Mamar, Roberta Fajka-Boja, Mónika Mórocz, et al.

Selected by 14 November 2023

Audrey Noireterre

Cancer Biology

NAD+ metabolism is a key modulator of bacterial respiratory epithelial infections

Björn Klabunde, André Wesener, Wilhelm Bertrams, et al.

Selected by 17 October 2023

Matheus Atella de Oliveira, Marcus Oliveira

Immunology

Glutamate helps unmask the differences in driving forces for phase separation versus clustering of FET family proteins in sub-saturated solutions

Mrityunjoy Kar, Laura T. Vogel, Gaurav Chauhan, et al.

Selected by 03 October 2023

Erich Sohn

Biochemistry

Polθ is phosphorylated by Polo-like kinase 1 (PLK1) to enable repair of DNA double strand breaks in mitosis

Camille Gelot, Marton Tibor Kovacs, Simona Miron, et al.

Selected by 05 June 2023

Pierre Caron

Molecular Biology
Alumni

Mitotic heritability of DNA methylation at intermediately methylated sites is imprecise

Amir D. Hay, Noah J. Kessler, Daniel Gebert, et al.

Selected by 24 March 2023

Samantha Seah et al.

Genetics

Single-strand mismatch and damage patterns revealed by single-molecule DNA sequencing

Mei Hong Liu, Benjamin Costa, Una Choi, et al.

Selected by 28 February 2023

Kerryn Elliott

Transcriptional units form the elementary constraining building blocks of the bacterial chromosome

Amaury Bignaud, Charlotte Cockram, Eric Allemand, et al.

Selected by 13 January 2023

Jennifer Ann Black

Microbiology

ATM-dependent formation of a novel chromatin compartment regulates the Response to DNA Double Strand Breaks and the biogenesis of translocations

Coline Arnould, Vincent Rocher, Aldo S. Bader, et al.

Selected by 17 February 2022

Jennifer Ann Black

Molecular Biology

cGAS recruitment to micronuclei is dictated by pre-existing nuclear chromatin status

Kate M. MacDonald, Shirony Nicholson-Puthenveedu, Maha M. Tageldein, et al.

Selected by 01 February 2022

Roberto Amadio

Cell Biology

Drag-and-drop genome insertion without DNA cleavage with CRISPR-directed integrases

Eleonora I. Ioannidi, Matthew T. N. Yarnall, Cian Schmitt-Ulms, et al.

Selected by 15 December 2021

Louise Moyle et al.

Genomics

CDK9 and PP2A regulate the link between RNA polymerase II transcription termination and RNA maturation

Michael Tellier, Justyna Zaborowska, Jonathan Neve, et al.

Selected by 02 November 2021

Isabella Maudlin

Molecular Biology

Lightning Fast and Highly Sensitive Full-Length Single-cell sequencing using FLASH-Seq

Vincent Hahaut, Dinko Pavlinic, Cameron Cowan, et al.

Selected by 12 August 2021

Jennifer Ann Black

Genomics
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