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A High Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury during the COVID-19 pandemic

Maria Alimova, Eriene-Heidi Sidhom, Abhigyan Satyam, et al.

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Anti-SARS-CoV-2 IgG from severely ill COVID-19 patients promotes macrophage hyper-inflammatory responses

Willianne Hoepel, Hung-Jen Chen, Sona Allahverdiyeva, et al.

Discussion

Conservation of the Toxoplasma conoid proteome in Plasmodium reveals a cryptic conoid feature that differentiates between blood- and vector-stage zoites

Ludek Koreny, Mohammad Zeeshan, Konstantin Barylyuk, et al.

An Atlas of Gene Regulatory Elements in Adult Mouse Cerebrum

Yang Eric Li, Sebastian Preissl, Xiaomeng Hou, et al.

Discussion

A subcellular atlas of Toxoplasma reveals the functional context of the proteome

Konstantin Barylyuk, Ludek Koreny, Huiling Ke, et al.

Human Hair Graying is Naturally Reversible and Linked to Stress

Ayelet Rosenberg, Shannon Rausser, Junting Ren, et al.

Mitochondrial fatty acid synthesis coordinates mitochondrial oxidative metabolism

Sara M. Nowinski, Ashley Solmonson, Scott F. Rusin, et al.

Interspecies differences in proteome turnover kinetics are correlated with lifespans and energetic demands

Kyle Swovick, Denis Firsanov, Kevin A. Welle, et al.

The Arabidopsis NOT4A E3 ligase coordinates PGR3 expression to regulate chloroplast protein translation

Mark Bailey, Aiste Ivanauskaite, Julia Grimmer, et al.

Split-TurboID enables contact-dependent proximity labeling in cells

Kelvin F. Cho, Tess C. Branon, Sanjana Rajeev, et al.

Obesity-driven changes in ECM composition promote local invasion and metastasis of breast tumors

Andrew Wishart, Yifan Peng, Sydney Conner, et al.

Discussion

Oligodendrocyte-derived exosomes promote axonal transport and axonal long-term maintenance

Carsten Frühbeis, Wen Ping Kuo-Elsner, Kerstin Barth, et al.

Synaptogenic activity of the axon guidance molecule Robo2 is critical for hippocampal circuit function

Heike Blockus, Sebastian V. Rolotti, Miklos Szoboszlay, et al.

Discussion