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Retrospective identification of rare cell populations underlying drug resistance connects molecular variability with cell fate

Benjamin L. Emert, Christopher Coté, Eduardo A. Torre, et al.

RAD50 promotes DNA repair by homologous recombination and restrains antigenic variation in African trypanosomes

Ann-Kathrin Mehnert, Marco Prorocic, Annick Dujeancourt-Henry, et al.

Loss of epithelial polarity redirects Notch signaling and triggers a Xrp1 response during neoplastic growth in Drosophila

Rémi Logeay, Charles Géminard, Patrice Lassus, et al.

KDM6B-dependent chromatin remodelling underpins effective virus-specific CD8⁺ T cell differentiation

Jasmine Li, Kristine Hardy, Moshe Olshansky, et al.

Senescence of alveolar stem cells drives progressive pulmonary fibrosis

Changfu Yao, Xiangrong Guan, Gianni Carraro, et al.

Polypyrimidine Tract Binding Proteins are essential for B cell development

Elisa Monzón-Casanova, Louise S. Matheson, Kristina Tabbada, et al.

The enteric nervous system of the human and mouse colon at a single-cell resolution

Eugene Drokhlyansky, Christopher S. Smillie, Nicholas Van Wittenberghe, et al.

Single Cell Gene Expression Analysis Reveals Human Stem Cell-Derived Graft Composition in a Cell Therapy Model of Parkinson’s Disease

Katarína Tiklová, Sara Nolbrant, Alessandro Fiorenzano, et al.

Single-cell RNA-sequencing reveals profibrotic roles of distinct epithelial and mesenchymal lineages in pulmonary fibrosis

Arun C. Habermann, Austin J. Gutierrez, Linh T. Bui, et al.

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Single Cell RNA-seq reveals ectopic and aberrant lung resident cell populations in Idiopathic Pulmonary Fibrosis

Taylor S. Adams, Jonas C. Schupp, Sergio Poli, et al.

Cross-species transcriptomic and epigenomic analysis reveals key regulators of injury response and neuronal regeneration in vertebrate retinas

Thanh Hoang, Jie Wang, Patrick Boyd, et al.

Hypoxia induces transcriptional and translational downregulation of the type I interferon (IFN) pathway in multiple cancer cell types

Ana Miar, Esther Arnaiz, Esther Bridges, et al.

Cholesterol and matrisome pathways dysregulated in human APOE ε4 glia

Julia TCW, Shuang A. Liang, Lu Qian, et al.