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Deletion of PIEZO1 in adult cardiomyocytes accelerates cardiac aging and causes premature death

Ze-Yan Yu, Yang Guo, Scott Kesteven, et al.

Discussion

A choroid plexus apocrine secretion mechanism shapes CSF proteome and embryonic brain development

Ya’el Courtney, Joshua P. Head, Elizabeth D. Yimer, et al.

Discussion

Tardigrades dramatically upregulate DNA repair pathway genes in response to ionizing radiation

Courtney M. Clark-Hachtel, Jonathan D. Hibshman, Tristan De Buysscher, et al.

Discussion

Planarians employ diverse and dynamic stem cell microenvironments to support whole-body regeneration

Blair W. Benham-Pyle, Frederick G. Mann Jr., Carolyn E. Brewster, et al.

Discussion

Sub-lethal apoptotic stress enables mtDNA release during senescence and drives the SASP

James Chapman, Hanna Salmonowicz, Stella Victorelli, et al.

Discussion

Polarized Dishevelled dissolution and condensation drives embryonic axis specification in oocytes

S. Zachary Swartz, Tzer Han Tan, Margherita Perillo, et al.

The nucleocytosolic O-fucosyltransferase Spindly affects protein expression and virulence in Toxoplasma gondii

Giulia Bandini, Carolina Agop-Nersesian, Hanke van der Wel, et al.

A Transcriptional Switch Governing Fibroblast Plasticity Underlies Reversibility of Chronic Heart Disease

Michael Alexanian, Pawel F. Przytycki, Rudi Micheletti, et al.

Discussion

Frizzled-dependent Planar Cell Polarity without Wnt Ligands

Joyce J.S. Yu, Aude Maugarny-Calès, Stéphane Pelletier, et al.

AND

Wnt ligands are not required for planar cell polarity in the Drosophila wing or notum

Ben Ewen-Campen, Typhaine Comyn, Eric Vogt, et al.

Autoregulatory circuit regulating basolateral cargo export from the TGN: role of the orphan receptor GPRC5A in PKD signaling and cell polarity

Rosaria Di Martino, Anita Capalbo, Lucia Sticco, et al.

Discussion

DYRK3-Controlled Phase Separation Organizes the Early secretory pathway

Raffaella Gallo, Arpan Rai, Lucas Pelkmans

Discussion

Molecular and cellular dissection of the OSBP cycle through a fluorescent inhibitor

Tiphaine Péresse, David Kovacs, Mélody Subra, et al.