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STING mediates immune responses in a unicellular choanoflagellate

Arielle Woznica, Ashwani Kumar, Carolyn R. Sturge, et al.

AND

The STING ligand 2’3’-cGAMP induces an NF-κB-dependent anti-bacterial innate immune response in the starlet sea anemone Nematostella vectensis

Shally R. Margolis, Peter A. Dietzen, Beth M. Hayes, et al.

Discussion

Vector-borne Trypanosoma brucei parasites develop in artificial human skin and persist as skin tissue forms

Christian Reuter, Fabian Imdahl, Laura Hauf, et al.

Mechanosensitivity of amoeboid cells crawling in 3D

Florian Gaertner, Patricia Reis-Rodrigues, Ingrid de Vries, et al.

Discussion

Remembering immunity: Neuronal ensembles in the insular cortex encode and retrieve specific immune responses

Tamar Koren, Maria Krot, Nadia T. Boshnak, et al.

Discussion

On-person adaptive evolution of Staphylococcus aureus during atopic dermatitis increases disease severity

Felix M. Key, Veda D. Khadka, Carolina Romo-González, et al.

Discussion

The force loading rate drives cell mechanosensing through both reinforcement and fluidization

Ion Andreu, Bryan Falcones, Sebastian Hurst, et al.

Antiviral activity of bacterial TIR domains via signaling molecules that trigger cell death

Gal Ofir, Ehud Herbst, Maya Baroz, et al.

Discussion

Ultrasensitive RNA biosensors for SARS-CoV-2 detection in a simple color and luminescence assay

Anirudh Chakravarthy, Anirudh K N, Geen George, et al.

Single cell transcriptomic analysis of bloodstream form Trypanosoma brucei reconstructs cell cycle progression and differentiation via quorum sensing

Emma M. Briggs, Richard McCulloch, Keith R. Matthews, et al.

Capacity to multitask limits cellular chemotaxis

Hye-ran Moon, Soutick Saha, Andrew Mugler, et al.

AMP-activated protein kinase: A key enzyme to manage nutritional stress responses in parasites with complex life cycles

Tamara Sternlieb, Alejandra C. Schoijet, Patricio D. Genta, et al.

Downstream of gasdermin D cleavage, a Ragulator-Rag-mTORC1 pathway promotes pore formation and pyroptosis

Charles L. Evavold, Iva Hafner-Bratkovič, Jonathan C. Kagan

Discussion