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Filtered by pharmacology and toxicology category

SQ3370, the first clinical click chemistry-activated cancer therapeutic, shows safety in humans and translatability across species

Sangeetha Srinivasan, Nathan A. Yee, Michael Zakharian, et al.

Selected by 06 May 2023

Zhang-He Goh

Pharmacology and Toxicology

Antimalarials in mosquitoes overcome Anopheles and Plasmodium resistance to malaria control strategies

Douglas G. , Alexandra S. , Erica, et al.

Selected by 19 August 2022

Nassif Seni, Helen Robertson

Immunology

Selective inhibitors of JAK1 targeting a subtype-restricted allosteric cysteine

Madeline E. Kavanagh, Benjamin D. Horning, Roli Khattri, et al.

Selected by 13 March 2022

Zhang-He Goh

Pharmacology and Toxicology

Discovery and visualization of uncharacterized drug-protein adducts using mass spectrometry

Michael Riffle, Michael R. Hoopmann, Daniel Jaschob, et al.

Selected by 10 July 2021

Zhang-He Goh

Pharmacology and Toxicology

Foldamers Reveal and Validate Novel Therapeutic Targets Associated with Toxic α-Synuclein Self-Assembly

Jemil Ahmed, Tessa C. Fitch, Courtney M. Donnelly, et al.

Selected by 05 June 2021

Joanna Zell

Biochemistry

Developmental exposure to domoic acid disrupts startle response behavior and circuitry

Jennifer M. Panlilio, Ian T. Jones, Matthew C. Salanga, et al.

Selected by 22 March 2021

Kirsten C. Sadler, Patrice Delaney

Pharmacology and Toxicology