Preprint highlights, selected by the biological community
The small RNA ErsA plays a role in the regulatory network of Pseudomonas aeruginosa pathogenicity in airways infection
Selected by
25 July 2020
Zhang-He Goh
Systematic analysis of protein targets associated with adverse events of drugs from clinical trials and post-marketing reports
AND
Toward in vivo-relevant hERG safety assessment and mitigation strategies based on relationships between non-equilibrium blocker binding, three-dimensional channel-blocker interactions, dynamic occupancy, dynamic exposure, and cellular arrhythmia
Selected by
13 July 2020
Zhang-He Goh
Preserved efficacy and reduced toxicity with intermittent linezolid dosing in combination with bedaquiline and pretomanid in a murine TB model
Selected by
01 July 2020
Zhang-He Goh
Ribosome rescue inhibitors clear Neisseria gonorrhoeae in vivo using a new mechanism
Selected by
18 June 2020
Zhang-He Goh
A therapeutic combination of two small molecule toxin inhibitors provides pancontinental preclinical efficacy against viper snakebite
Selected by
29 May 2020
Zhang-He Goh
Broad-spectrum antivirals of protoporphyrins inhibit the entry of highly pathogenic emerging viruses
Selected by
23 May 2020
Zhang-He Goh