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Antifungal effects of PC945, a novel inhaled triazole, on Candida albicans-infected immunocompromised mice

Yuki Nishimoto, Kazuhiro Ito, Genki Kimura, et al.

Genome-wide CRISPRi/a screens in human neurons link lysosomal failure to ferroptosis

Ruilin Tian, Anthony Abarientos, Jason Hong, et al.

DMD-based super-resolution structured illumination microscopy visualizes live cell dynamics at high speed and low cost

Alice Sandmeyer, Mario Lachetta, Hauke Sandmeyer, et al.

Toll-like receptor 4 is activated by platinum and contributes to cisplatin-induced ototoxicity

Ghazal Babolmorad, Asna Latif, Niall M. Pollock, et al.

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Application of the in vivo oxidative stress reporter Hmox1 as mechanistic biomarker of arsenic toxicity

Francisco Inesta-Vaquera, Panida Navasumrit, Colin J. Henderson, et al.

Amyotrophic lateral sclerosis associated mislocalisation of TDP-43 to the cytoplasm causes cortical hyperexcitability and reduced excitatory neurotransmission in the motor cortex

MS Dyer, KE Lewis, AK Walker, et al.

The First Mitotic Division of the Human Embryo is Highly Error-prone

Emma Ford, Cerys E. Currie, Deborah M. Taylor, et al.

Electron Transfer from Cytochrome P450 Reductase to Cytochrome P450: Towards a Structural and Dynamic Understanding

Goutam Mukherjee, Prajwal P. Nandekar, Rebecca C. Wade

Transcription repressor protein ZBTB25 interacts with HDAC1 in macrophages infected with Mycobacterium tuberculosis, and its inhibition leads to autophagy and killing of the intracellular pathogen

Aravind Madhavan, K B Arun, Akhil Raj Pushparajan, et al.

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Tamoxifen reduces inflammatory infiltration of neutrophils in the airways

Agustín Mansilla, Jaime Soto, Claudio Henríquez, et al.

The small RNA ErsA plays a role in the regulatory network of Pseudomonas aeruginosa pathogenicity in airways infection

Silvia Ferrara, Alice Rossi, Serena Ranucci, et al.

Systematic analysis of protein targets associated with adverse events of drugs from clinical trials and post-marketing reports

Ines A. Smit, Avid M. Afzal, Chad H. G. Allen, et al.

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Toward in vivo-relevant hERG safety assessment and mitigation strategies based on relationships between non-equilibrium blocker binding, three-dimensional channel-blocker interactions, dynamic occupancy, dynamic exposure, and cellular arrhythmia

Hongbin Wan, Gianluca Selvaggio, Robert A. Pearlstein

Miniaturized Devices for Bioluminescence Imaging in Freely Behaving Animals

Dmitrijs Celinskis, Nina Friedman, Mikhail Koksharov, et al.

Practical Fluorescence Reconstruction Microscopy for Large Samples and Low-Magnification Imaging

Julienne LaChance, Daniel J. Cohen