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Epigenetic rewriting at centromeric DNA repeats leads to increased chromatin accessibility and chromosomal instability

Sheldon Decombe, François Loll, Laura Caccianini, et al.

Selected by 18 April 2021

Sree Rama Chaitanya

Cell Biology

m6A RNA methylation facilitates pre-mRNA 3’-end formation and is essential for viability of Toxoplasma gondii

Michael J. Holmes, Leah R. Padgett, Matheus S. Bastos, et al.

AND

A plant-like mechanism coupling m6A reading to polyadenylation safeguards transcriptome integrity and developmental genes partitioning in Toxoplasma

Dayana C. Farhat, Matthew Bowler, Guillaume Communie, et al.

Selected by 22 March 2021

Joao Mello-Vieira

Microbiology

The force loading rate drives cell mechanosensing through both reinforcement and fluidization

Ion Andreu, Bryan Falcones, Sebastian Hurst, et al.

Selected by 20 March 2021

Jessica L. Teo

Biophysics

A systematic analysis of Trypanosoma brucei chromatin factors identifies novel protein interaction networks associated with sites of transcription initiation and termination

Desislava P. Staneva, Roberta Carloni, Tatsiana Auchynnikava, et al.

Selected by 11 March 2021

Tamara Sternlieb

Cell Biology

Crosstalk between H2A variant-specific modifications impacts vital cell functions

Anna Schmücker, Bingkun Lei, Zdravko J. Lorković, et al.

Selected by 06 March 2021

Pravrutha Raman, Harmit Malik

Synthetic Biology

The chromatin, topological and regulatory properties of pluripotency-associated poised enhancers are conserved in vivo

Giuliano Crispatzu, Rizwan Rehimi, Tomas Pachano, et al.

Selected by 17 February 2021

Sergio Menchero

Molecular Biology

Mitotic R-loops direct Aurora B kinase to maintain centromeric cohesion

Erin C. Moran, Limin Liu, Ewelina Zasadzinska, et al.

Selected by 10 February 2021

Jennifer Ann Black

Cell Biology

FUS-dependent liquid-liquid phase separation is an early event in double-strand break repair

Brunno R. Levone, Silvia C. Lenzken, Marco Antonaci, et al.

Selected by 05 February 2021

Sree Rama Chaitanya, Giuseppina D'Alessandro

Cell Biology

A developmentally programmed splicing failure attenuates the DNA damage response during mammalian zygotic genome activation

Christopher D. R. Wyatt, Barbara Pernaute, André Gohr, et al.

Selected by 05 February 2021

Sree Rama Chaitanya

Developmental Biology

Precise genomic deletions using paired prime editing

Junhong Choi, Wei Chen, Chase C. Suiter, et al.

Selected by 27 January 2021

Fabio Liberante

Genomics

Neuronal Enhancers are Hotspots For DNA Single-Strand Break Repair

Wei Wu, Sarah E. Hill, William J. Nathan, et al.

Selected by 06 January 2021

Giuseppina D'Alessandro, Sree Rama Chaitanya

Cell Biology

ALC1 links chromatin accessibility to PARP inhibitor response in homologous recombination deficient cells

Priyanka Verma, Yeqiao Zhou, Zhendong Cao, et al.

Selected by 31 December 2020

Giuseppina D'Alessandro

Cancer Biology
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