Preprint highlights, selected by the biological community
ASCB | EMBO Cell Bio *virtual* 2020
Preprints + open discussions related to work presented at Cell Bio 2020 in December
List by Dey Lab, Mariana De Niz, Amanda Haage, Federico Pelisch, Maiko Kitaoka, Ankita Jha, Giuliana Clemente, Madhuja Samaddar, Angika Basant
Preprints:
The nature of mitotic forces in epithelial monolayers
https://www.biorxiv.org/content/10.1101/2020.11.16.378927v2
Mechanobiology of collective cell behaviour
CYRI-A regulates macropinocytic cup maturation and mediates integrin uptake, limiting invasive migration
CYRI-A as a key regulator of macropinocytosis maturation and integrin internalisation from the cell surface.
Rab34 GTPase mediates ciliary membrane biogenesis in the intracellular ciliogenesis pathway
A flagellate-to-amoeboid switch in the closest living relatives of animals
https://www.biorxiv.org/content/10.1101/2020.06.26.171736v1.full
Bistable, biphasic regulation of PP2A-B55 accounts for the dynamics of mitotic substrate phosphorylation
α-catenin switches between a slip and a cooperative catch bond with F-actin to regulate cell junction fluidity
Unanticipated diversity, undiscovered ancient paralogs, and Asgard origins of the ARF GTPase protein family
Cell clusters adopt a collective amoeboid mode of migration in confined non-adhesive environments
Tau, XMAP215/Msps and Eb1 jointly regulate microtubule polymerisation and bundle formation in axons
Apical PAR complex proteins protect against epithelial assaults to create a continuous and functional intestinal lumen
Desmosomes pattern cell mechanics to govern epidermal tissue form and function
Initial ciliary assembly in Chlamydomonas requires Arp2/3-dependent recruitment from a ciliary protein reservoir in the plasma membrane
Physical properties of the cytoplasm modulate the rates of microtubule growth and shrinkage
Tension promotes kinetochore-microtubule release in response to Aurora B activity
https://www.biorxiv.org/content/10.1101/2020.06.01.127795v1.full
Centrosome amplification mediates small extracellular vesicles secretion via lysosome disruption
Centromere drive and suppression by parallel pathways for recruiting microtubule destabilizers
A rapidly evolving actin mediates fertility and developmental tradeoffs in Drosophila
Arp2/3 complex-mediated actin assembly drives microtubule-independent motility and phagocytosis in the evolutionarily divergent amoeba Naegleria
Posted on: 3 December 2020 , updated on: 14 December 2020
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