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Madhuja Samaddar

Calico Life Sciences

I’m a cell biologist interested in protein homeostasis and cellular quality control pathways, and their impairment during extraneous stress, disease and aging. Currently as a postdoctoral fellow at Calico Life Sciences, I use C. elegans to study how germ cells tackle protein quality control during maturation to ensure a healthy proteome required for germline immortality. During my PhD training at Indian Institute of Science, I studied mitochondrial protein import and folding in maintenance of organelle function and homeostasis, and in context of neurodegenerative diseases such as Parkinson’s disease.

Outside of research, I enjoy engaging in science outreach with the overall goal of promoting science and technology education and supporting professional careers in STEM fields. I actively volunteer for organizations including Women in Bio (Membership Committee Chair, San Francisco chapter), The American Society for Cell Biology (ASCB Ambassador) and Science Buddies (Expert, ‘Ask an Expert’ Program). At preLights, I’m excited to be a voice for ECRs and contribute my part to open and accessible science. 

Madhuja Samaddar has added 5 preLight posts

Parental genome unification is highly erroneous in mammalian embryos

Tommaso Cavazza, Antonio Z Politi, Patrick Aldag, et al.

Selected by 14 September 2020

Madhuja Samaddar

Cell Biology

FUS gene is dual-coding with both proteins united in FUS-mediated toxicity

Marie A. Brunet, Jean-Francois Jacques, Sonya Nassari, et al.

Selected by 12 May 2020

Madhuja Samaddar

Molecular Biology

Yeast FIT2 homolog is necessary to maintain cellular proteostasis by regulating lipid homeostasis

Peter Shyu, Wei Sheng Yap, Maria L. Gaspar, et al.

Selected by 26 April 2020

Madhuja Samaddar

Genetics

Small molecules for modulating protein driven liquid-liquid phase separation in treating neurodegenerative disease

Richard J. Wheeler, Hyun O. Lee, Ina Poser, et al.

Selected by 30 August 2019

Madhuja Samaddar

Cell Biology

Cross-kingdom recognition of bacterial small RNAs induces transgenerational pathogenic avoidance

Rachel Kaletsky, Rebecca S. Moore, Lance L. Parsons, et al.

Selected by 27 July 2019

Madhuja Samaddar

Molecular Biology

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