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ASCB EMBO Annual Meeting 2019

A collection of preprints presented at the 2019 ASCB EMBO Meeting in Washington, DC (December 7-11)

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Mitochondrial volume fraction and translation speed impact mRNA localization and production of nuclear-encoded mitochondrial proteins

Tatsuhisa Tsuboi, Matheus P. Viana, Fan Xu, Jingwen Yu, Raghav Chanchani, Ximena G. Arceo, Evelina Tutucci, Joonhyuk Choi, Yang S. Chen, Robert H. Singer, Susanne M. Rafelski, Brian M. Zid

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WAVE complex self-organization templates lamellipodial formation

Anne Pipathsouk, Rachel M. Brunetti, Jason P. Town, Artù Breuer, Patrina A. Pellett, Kyle Marchuk, Ngoc-Han T. Tran, Matthew F. Krummel, Dimitrios Stamou, Orion D. Weiner

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Exploring endocytic compartment morphology with systematic genetics and single cell image analysis

Mojca Mattiazzi Usaj, Nil Sahin, Helena Friesen, Carles Pons, Matej Usaj, Myra Paz Masinas, Ermira Shuteriqi, Aleksei Shkurin, Patrick Aloy, Quaid Morris, Charles Boone, Brenda J. Andrews

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Correlative three-dimensional super-resolution and block face electron microscopy of whole vitreously frozen cells

David P. Hoffman, Gleb Shtengel, C. Shan Xu, Kirby R. Campbell, Melanie Freeman, Lei Wang, Daniel E. Milkie, H. Amalia Pasolli, Nirmala Iyer, John A. Bogovic, Daniel R. Stabley, Abbas Shirinifard, Song Pang, David Peale, Kathy Schaefer, Wim Pomp, Chi-Lun Chang, Jennifer Lippincott-Schwartz, Tom Kirchhausen, David J. Solecki, Eric Betzig, Harald Hess

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The Glycolytic Protein Phosphofructokinase Dynamically Relocalizes into Subcellular Compartments with Liquid-like Properties in vivo

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Biophysical properties of intermediate states of EMT outperform both epithelial and mesenchymal states

Yoran Margaron, Tomoaki Nagai, Laurent Guyon, Laetitia Kurzawa, Anne-Pierre Morel, Alice Pinheiro, Laurent Blanchoin, Fabien Reyal, Alain Puisieux, Manuel Théry

https://www.biorxiv.org/content/10.1101/797654v1

Cross-kingdom recognition of bacterial small RNAs induces transgenerational pathogenic avoidance

Rachel Kaletsky, Rebecca S. Moore, Lance L. Parsons, Coleen T. Murphy

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Self-assembly of multi-component mitochondrial nucleoids via phase separation

Marina Feric, Tyler G. Demarest, Jane Tian, Deborah L. Croteau, Vilhelm A. Bohr, Tom Misteli

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Material aging causes centrosome weakening and disassembly during mitotic exit

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Spatial control of nucleoporin assembly by Fragile X-related proteins

Arantxa Agote-Arán, Stephane Schmucker, Katerina Jerabkova, Inès Jmel Boyer, Alessandro Berto, Laura Pacini, Paolo Ronchi, Charlotte Kleiss, Laurent Guerard, Yannick Schwab, Hervé Moine, Jean-Louis Mandel, Sebastien Jacquemont, Claudia Bagni, Izabela Sumara

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Cohesin and condensin extrude loops in a cell-cycle dependent manner

Stefan Golfier, Thomas Quail, Hiroshi Kimura, Jan Brugués

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Transposable elements drive reorganisation of 3D chromatin during early embryogenesis

Kai Kruse, Noelia Díaz, Rocio Enriquez-Gasca, Xavier Gaume, Maria-Elena Torres-Padilla, Juan M. Vaquerizas

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A chromosome folding intermediate at the condensin-to-cohesin transition during telophase

Kristin Abramo, Anne-Laure Valton, Sergey V. Venev, Hakan Ozadam, A. Nicole Fox, Job Dekker

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Cryo-ET analysis of budding yeast synaptonemal complexes in situ

Olivia X. Ma, Shujun Cai, Jian Shi, Lu Gan

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Nuclear actin cable with multiple branches during yeast meiosis

Tomoko Takagi, Masako Osumi, Akira Shinohara

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Mutant lamins cause nuclear envelope rupture and DNA damage in skeletal muscle cells

Ashley J. Earle, Tyler J. Kirby, Gregory R. Fedorchak, Philipp Isermann, Jineet Patel, Sushruta Iruvanti, Steven A. Moore, Gisèle Bonne, Lori L. Wallrath, Jan Lammerding

https://www.biorxiv.org/content/10.1101/364778v5

Unrestrained ESCRT-III drives chromosome fragmentation and micronuclear catastrophe

Marina Vietri, Sebastian W. Schultz, Aurélie Bellanger, Carl M. Jones, Camilla Raiborg, Ellen Skarpen, Christeen Ramane J. Pedurupillay, Eline Kip, Romy Timmer, Ashish Jain, Philippe Collas, Roland L. Knorr, Sushma N. Grellscheid, Halim Kusumaatmaja, Andreas Brech, Francesca Micci, Harald Stenmark, Coen Campsteijn

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An ESCRT-LEM domain inner nuclear membrane protein surveillance system is poised to directly monitor the integrity of the nuclear envelope barrier and nuclear transport system

David J. Thaller, Matteo Allegretti, Sapan Borah, Paolo Ronchi, Martin Beck, C. Patrick Lusk

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Cytoplasmic volume and limiting nucleoplasmin scale nuclear size during Xenopus laevis development

Pan Chen, Miroslav Tomschik, Katherine Nelson, John Oakey, J. C. Gatlin, Daniel L. Levy

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Centrosome and ciliary abnormalities in fetal akinesia deformation sequence human fibroblasts

Ramona Jühlen, Jeroen Breckpot, Birthe Fahrenkrog

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Mitochondrial volume fraction and translation speed impact mRNA localization and production of nuclear-encoded mitochondrial proteins

Tatsuhisa Tsuboi, Matheus P. Viana, Fan Xu, Jingwen Yu, Raghav Chanchani, Ximena G. Arceo, Evelina Tutucci, Joonhyuk Choi, Yang S. Chen, Robert H. Singer, Susanne M. Rafelski, Brian M. Zid

https://www.biorxiv.org/content/10.1101/529289v2

Novel cytokinetic ring components limit RhoA activity and contractility

Kathryn Rehain Bell, Michael E. Werner, Anusha Doshi, Daniel B. Cortes, Adam Sattler, Thanh Vuong-Brender, Michel Labouesse, Amy Shaub Maddox

https://www.biorxiv.org/content/10.1101/633743v1

Insights from a survey-based analysis of the academic job market

Jason D. Fernandes, Sarvenaz Sarabipour, Christopher T. Smith, Natalie M. Niemi, Nafisa M. Jadavji, Ariangela J. Kozik, Alex S. Holehouse, Vikas Pejaver, Orsolya Symmons, Alexandre W. Bisson Filho, Amanda Haage

https://www.biorxiv.org/content/10.1101/796466v2

Twinfilin uncaps filament barbed ends to promote turnover of lamellipodial actin networks

Markku Hakala, Hugo Wioland, Mari Tolonen, Antoine Jegou, Guillaume Romet-Lemonne, Pekka Lappalainen

https://www.biorxiv.org/content/10.1101/864769v1

CLASP mediates microtubule repair by promoting tubulin incorporation into damaged lattices

Amol Aher, Dipti Rai, Laura Schaedel, Jeremie Gaillard, Karin John, Laurent Blanchoin, Manuel Thery, Anna Akhmanova

https://www.biorxiv.org/content/10.1101/809251v1.article-info

A Combinatorial MAP Code Dictates Polarized Microtubule Transport

Brigette Y. Monroy, Tracy C. Tan, Janah May Oclaman, Jisoo S. Han, Sergi Simo, Dan W. Nowakowski, Richard J. McKenney, Kassandra M. Ori-McKenney

https://www.biorxiv.org/content/10.1101/731604v1

Connectivity analysis of GEF/GTPase networks in living cells

D.J. Marston, M. Vilela, Jinqi Ren, George Glekas, Mihai Azotei, G. Danuser, J. Sondek, K.M. Hahn

https://www.biorxiv.org/content/10.1101/728998v1

Profilin 1 Controls the Assembly, Organization, and Dynamics of Leading Edge Actin Structures Through Internetwork Competition and Collaboration

Kristen Skruber, Peyton V. Warp, Rachael Shklyarov, James D. Thomas, Maurice S. Swanson, Jessica L. Henty-Ridilla, Tracy-Ann Read, Eric A. Vitriol

https://www.biorxiv.org/content/10.1101/849356v1

The mitotic crosslinking protein PRC1 acts as a mechanical dashpot to resist microtubule sliding

Ignas Gaska, Mason Armstrong, April Alfieri, Scott Forth

https://www.biorxiv.org/content/10.1101/2019.12.12.874529v1

Unconventional kinetochore kinases KKT2 and KKT3 have a unique zinc finger that promotes their kinetochore localization

Gabriele Marcianò, Olga O. Nerusheva, Midori Ishii, Bungo Akiyoshi

https://www.biorxiv.org/content/10.1101/2019.12.13.875419v1

Cryo-ET analysis of budding yeast synaptonemal complexes in situ

Olivia X. Ma, Shujun Cai, Jian Shi, Lu Gan

https://www.biorxiv.org/content/10.1101/746982v1

PCH-2TRIP13 regulates spindle checkpoint strength

Lénaïg Défachelles, Anna E. Russo, Christian R. Nelson, Needhi Bhalla

https://www.biorxiv.org/content/10.1101/389080v3

A deeper understanding of intestinal organoid metabolism revealed by combining fluorescence lifetime imaging microscopy (FLIM) and extracellular flux analyses

Irina A. Okkelman, Nuno Neto, Dmitri B. Papkovsky, Michael Monaghan, Ruslan I. Dmitriev

https://www.biorxiv.org/content/10.1101/771188v1

Categories: biochemistry , bioengineering , biophysics , cancer biology , cell biology , developmental biology , molecular biology , neuroscience , scientific communication and education , systems biology

 

Posted on: 8th December 2019 , updated on: 20th December 2019

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    Rachel L Graves, Abeed Sarker, Mohammed Ali Al-Garadi, et al.



    Selected by Zhang-He Goh

    Also in the systems biology category:

    Retrospective identification of rare cell populations underlying drug resistance connects molecular variability with cell fate

    Benjamin L. Emert, Christopher Coté, Eduardo A. Torre, et al.



    Selected by Pavithran Ravindran

    SIV and Mycobacterium tuberculosis synergy within the granuloma accelerates the reactivation pattern of latent tuberculosis

    Collin R Diedrich, Tara Rutledge, Pauline Maiello, et al.



    Selected by Louise Fraser

    A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing

    David E. Gordon, Gwendolyn M. Jang, Mehdi Bouhaddou, et al.



    Selected by Robert Mahen

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