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MitoList
This list of preprints is focused on work expanding our knowledge on mitochondria in any organism, tissue or cell type, from the normal biology to the pathology.
List by Sandra Franco Iborra
Preprints:
Mitochondrial fusion in reactive astrocytes coordinates local metabolic domains to promote vascular repair
https://www.biorxiv.org/content/10.1101/657999v1?rss=1
In the context of injured central nervous system, dysfunction in the blood-brain barrier (BBB) is starting to gain some attention. BBB is formed by the brain endothelial cells, pericytes and astrocytes’ end-feet processes. It has been already shown that astrocytes, upon injury, can adapt their metabolic state modifying the architecture of the mitochondrial network. In this preprint, authors provide evidence of the importance of this mitochondrial network remodeling in astrocytes’ processes to ellicit vascular repair in the injured area.
Mitochondria form cholesterol tethered contact sites with the Nucleus to regulate retrograde response
https://www.biorxiv.org/content/10.1101/445411v2
Contact sites between mitochondria and many organelles are being unraveled. Those contact sites are believed to play an important role in lipid and ion exchange, membrane dynamics and signalling. This preprint highlights the presence of a specific tethering between mitochondria and the nucleus based in cholesterol.
Profound functional and molecular diversity of mitochondria revealed by cell type-specific profiling in vivo
https://www.biorxiv.org/content/10.1101/403774v1
We are all aware about the different mitochondrial morphologies that can take place in different cell types. But what about molecular differences? In this preprint Fecher et al., developed a method to isolate cell type-specific mitochondria from the MitoTag mouse and analyzed the proteome landscape of mitochondria from different tissues.
Mitochondria-derived vesicles deliver antimicrobial payload to control phagosomal bacteria
https://www.biorxiv.org/content/10.1101/277004v1
Mitochondria-derived vesicles (MDV) have been reported to transport mitochondrial components to other intracellular compartments. MDV are described as a quality control system for mitochondria. However, in this preprint, Abuaita et al. describe a new function for MDVs in enhancing macrophage antimicrobial funcion.
Presynaptic boutons that contain mitochondria are more stable
https://www.biorxiv.org/content/10.1101/580530v1
Mitochondria localization in presynaptic structures is positively correlated with synaptic efficacy. Here, authors focus on the study of mitochondrial spatial distribution to presynaptic boutons and how this related to presynaptic structure plasticity. Interestingly, studies are carried in mice using in vivo two-photon imaging.
Mitochondria-Associated Membranes (MAMs) are involved in Bax mitochondrial localization and cytochrome c release
https://www.biorxiv.org/content/10.1101/443606v1
Mitochondria-Associated Membranes or MAM are specific microdomains in ER membrane in close contact to the outer mitochondrial membrane. MAMs are sites of ER and mitochondria communication via lipid synthesis or calcium transfer. In this preprint, authors study the role of MAM stability in Bax localization and implicate this highly dynamic compartment in the regulation of apoptosis.
Categories: biochemistry , cell biology , molecular biology
Posted on: 20th May 2019 , updated on: 6th June 2019
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MitoList
This list of preprints is focused on work expanding our knowledge on mitochondria in any organism, tissue or cell type, from the normal biology to the pathology.
| List by | Sandra Franco Iborra |
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| List by | Joseph Jose Thottacherry |
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| List by | Dey Lab, Amanda Haage |
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A list of preprints mentioned at the #EESmorphoG virtual meeting in 2021.
| List by | Alex Eve |
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A collection of preprints presented during the virtual meeting of the Federation of European Neuroscience Societies (FENS) in 2020
| List by | Ana Dorrego-Rivas |
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Preprints presented at 15th European Conference on Fungal Genetics 17-20 February 2020 Rome
| List by | Hiral Shah |
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A collection of preprints presented at the 2019 ASCB EMBO Meeting in Washington, DC (December 7-11)
| List by | Madhuja Samaddar et al. |
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MitoList
This list of preprints is focused on work expanding our knowledge on mitochondria in any organism, tissue or cell type, from the normal biology to the pathology.
| List by | Sandra Franco Iborra |
Also in the biochemistry category:
Also in the cell biology category:
Nuclear soluble cGAS senses DNA virus infection
| Selected by | Roberto Amadio |
1
Analysis of subcellular transcriptomes by RNA proximity labeling with Halo-seq
| Selected by | Ashleigh Davey |
1
Three-axis classification of mouse lung mesenchymal cells reveals two populations of myofibroblasts
| Selected by | Sagar Varankar |
1
Also in the molecular biology category:
Nuclear soluble cGAS senses DNA virus infection
| Selected by | Roberto Amadio |
1
Analysis of subcellular transcriptomes by RNA proximity labeling with Halo-seq
| Selected by | Ashleigh Davey |
1
Cellular chaining influences biofilm formation and structure in Group A Streptococcus
| Selected by | SCELSE Summer School |