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MitoList
This list of preprints is focused on work expanding our knowledge on mitochondria in any organism, tissue or cell type, from the normal biology to the pathology.
List by Sandra Franco Iborra
Preprints:
Mitochondrial fusion in reactive astrocytes coordinates local metabolic domains to promote vascular repair
https://www.biorxiv.org/content/10.1101/657999v1?rss=1
In the context of injured central nervous system, dysfunction in the blood-brain barrier (BBB) is starting to gain some attention. BBB is formed by the brain endothelial cells, pericytes and astrocytes’ end-feet processes. It has been already shown that astrocytes, upon injury, can adapt their metabolic state modifying the architecture of the mitochondrial network. In this preprint, authors provide evidence of the importance of this mitochondrial network remodeling in astrocytes’ processes to ellicit vascular repair in the injured area.
Mitochondria form cholesterol tethered contact sites with the Nucleus to regulate retrograde response
https://www.biorxiv.org/content/10.1101/445411v2
Contact sites between mitochondria and many organelles are being unraveled. Those contact sites are believed to play an important role in lipid and ion exchange, membrane dynamics and signalling. This preprint highlights the presence of a specific tethering between mitochondria and the nucleus based in cholesterol.
Profound functional and molecular diversity of mitochondria revealed by cell type-specific profiling in vivo
https://www.biorxiv.org/content/10.1101/403774v1
We are all aware about the different mitochondrial morphologies that can take place in different cell types. But what about molecular differences? In this preprint Fecher et al., developed a method to isolate cell type-specific mitochondria from the MitoTag mouse and analyzed the proteome landscape of mitochondria from different tissues.
Mitochondria-derived vesicles deliver antimicrobial payload to control phagosomal bacteria
https://www.biorxiv.org/content/10.1101/277004v1
Mitochondria-derived vesicles (MDV) have been reported to transport mitochondrial components to other intracellular compartments. MDV are described as a quality control system for mitochondria. However, in this preprint, Abuaita et al. describe a new function for MDVs in enhancing macrophage antimicrobial funcion.
Presynaptic boutons that contain mitochondria are more stable
https://www.biorxiv.org/content/10.1101/580530v1
Mitochondria localization in presynaptic structures is positively correlated with synaptic efficacy. Here, authors focus on the study of mitochondrial spatial distribution to presynaptic boutons and how this related to presynaptic structure plasticity. Interestingly, studies are carried in mice using in vivo two-photon imaging.
Mitochondria-Associated Membranes (MAMs) are involved in Bax mitochondrial localization and cytochrome c release
https://www.biorxiv.org/content/10.1101/443606v1
Mitochondria-Associated Membranes or MAM are specific microdomains in ER membrane in close contact to the outer mitochondrial membrane. MAMs are sites of ER and mitochondria communication via lipid synthesis or calcium transfer. In this preprint, authors study the role of MAM stability in Bax localization and implicate this highly dynamic compartment in the regulation of apoptosis.
Categories: biochemistry , cell biology , molecular biology
Posted on: 20th May 2019 , updated on: 6th June 2019
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Register hereAlso in the biochemistry category:
ASCB EMBO Annual Meeting 2019
A collection of preprints presented at the 2019 ASCB EMBO Meeting in Washington, DC (December 7-11)
| List by | Madhuja Samaddar, Ramona Jühlen, Amanda Haage, Laura McCormick, Maiko Kitaoka |
EMBL Seeing is Believing – Imaging the Molecular Processes of Life
Preprints discussed at the 2019 edition of Seeing is Believing, at EMBL Heidelberg from the 9th-12th October 2019
| List by | Gautam Dey |
Cellular metabolism
A curated list of preprints related to cellular metabolism at Biorxiv by Pablo Ranea Robles from the Prelights community. Special interest on lipid metabolism, peroxisomes and mitochondria.
| List by | Pablo Ranea Robles |
Also in the cell biology category:
BioMalPar XVI: Biology and Pathology of the Malaria Parasite
[under construction] Preprints presented at the (fully virtual) EMBL BioMalPar XVI, 17-18 May 2020 #emblmalaria
| List by | Gautam Dey, Samantha Seah |
1
Cell Polarity
Recent research from the field of cell polarity is summarized in this list of preprints. It comprises of studies focusing on various forms of cell polarity ranging from epithelial polarity, planar cell polarity to front-to-rear polarity.
| List by | Yamini Ravichandran |
TAGC 2020
Preprints recently presented at the virtual Allied Genetics Conference, April 22-26, 2020. #TAGC20
| List by | Maiko Kitaoka, Madhuja Samaddar, Miguel V. Almeida, Sejal Davla, Jennifer Ann Black, Gautam Dey |
3D Gastruloids
A curated list of preprints related to Gastruloids (in vitro models of early development obtained by 3D aggregation of embryonic cells)
| List by | Paul Gerald L. Sanchez and Stefano Vianello |
ECFG15 – Fungal biology
Preprints presented at 15th European Conference on Fungal Genetics 17-20 February 2020 Rome
| List by | Hiral Shah |
ASCB EMBO Annual Meeting 2019
A collection of preprints presented at the 2019 ASCB EMBO Meeting in Washington, DC (December 7-11)
| List by | Madhuja Samaddar, Ramona Jühlen, Amanda Haage, Laura McCormick, Maiko Kitaoka |
EMBL Seeing is Believing – Imaging the Molecular Processes of Life
Preprints discussed at the 2019 edition of Seeing is Believing, at EMBL Heidelberg from the 9th-12th October 2019
| List by | Gautam Dey |
Autophagy
Preprints on autophagy and lysosomal degradation and its role in neurodegeneration and disease. Includes molecular mechanisms, upstream signalling and regulation as well as studies on pharmaceutical interventions to upregulate the process.
| List by | Sandra Malmgren Hill |
Lung Disease and Regeneration
This preprint list compiles highlights from the field of lung biology.
| List by | Rob Hynds |
BSCB/BSDB Annual Meeting 2019
Preprints presented at the BSCB/BSDB Annual Meeting 2019
| List by | Gautam Dey |
MitoList
This list of preprints is focused on work expanding our knowledge on mitochondria in any organism, tissue or cell type, from the normal biology to the pathology.
| List by | Sandra Franco Iborra |
Biophysical Society Annual Meeting 2019
Few of the preprints that were discussed in the recent BPS annual meeting at Baltimore, USA
| List by | Joseph Jose Thottacherry |
ASCB/EMBO Annual Meeting 2018
This list relates to preprints that were discussed at the recent ASCB conference.
| List by | Gautam Dey, Amanda Haage |
Also in the molecular biology category:
ECFG15 – Fungal biology
Preprints presented at 15th European Conference on Fungal Genetics 17-20 February 2020 Rome
| List by | Hiral Shah |
ASCB EMBO Annual Meeting 2019
A collection of preprints presented at the 2019 ASCB EMBO Meeting in Washington, DC (December 7-11)
| List by | Madhuja Samaddar, Ramona Jühlen, Amanda Haage, Laura McCormick, Maiko Kitaoka |
Lung Disease and Regeneration
This preprint list compiles highlights from the field of lung biology.
| List by | Rob Hynds |
MitoList
This list of preprints is focused on work expanding our knowledge on mitochondria in any organism, tissue or cell type, from the normal biology to the pathology.
| List by | Sandra Franco Iborra |
Also in the biochemistry category:
Also in the cell biology category:
Membrane bending by protein phase separation
| Selected by | Gautam Dey |
1
L-bodies are novel RNA-protein condensates driving RNA transport in Xenopus oocytes
| Selected by | Maiko Kitaoka |
Recognition of cellular RNAs by the S9.6 antibody creates pervasive artefacts when imaging RNA:DNA hybrids
| Selected by | Ram |
1
Also in the molecular biology category:
Human Hair Graying is Naturally Reversible and Linked to Stress
| Selected by | Sruthi Balakrishnan |
1
Organoid Easytag: an efficient workflow for gene targeting in human organoids
| Selected by | Kirsty Ferguson |
1
Stem-cell niche self-restricts the signaling range via receptor-ligand degradation
| Selected by | Nadia Edelsztein |