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Biophysical Society Annual Meeting 2019
Few of the preprints that were discussed in the recent BPS annual meeting at Baltimore, USA
List by Joseph Jose Thottacherry
Preprints:
Myosin-II mediated traction forces evoke localized Piezo1 Ca2+ flickers
https://www.biorxiv.org/content/10.1101/294611v2
Piezo 1 channels are mobile at the plasma membrane and releases calcium in response to local traction forces.
Tumor suppressor DAPK1 catalyzes Adhesion Assembly on Rigid but Anoikis on Soft Matrices
https://www.biorxiv.org/content/10.1101/320739v2.full
DAPK1 is important for adhesion assembly on rigid surfaces and apoptosis on soft surfaces (anoikis) through its binding to rigidity-sensing modules.
Ligand Geometry Controls Adhesion formation via Integrin Clustering
https://www.biorxiv.org/content/10.1101/435826v1
This study uses nanopatterning to mimic ECM fibers to study cell adhesion and shows that unliganded integrins can co-cluster to bridge between thin matrix fibers and thus form stable integrin adhesions on dense fibrous networks.
Synaptic vesicles undock and then transiently dock after an action potential
https://www.biorxiv.org/content/10.1101/509216v1
This study utilizes high pressure freezing and electron microscopy following an action potential in neurons to capture rapid synaptic vesicle fusions and unexpected docking dynamics.
Cell cycle repression and DNA repair defects follow constricted migration
https://www.biorxiv.org/content/10.1101/240838v1
Cell migration into tissue or narrow capillaries often elongates the nucleus and sometimes damages it and this study shows that it impacts cell cycle as well as causes DNA damage.
Rescue of DNA damage in cells after constricted migration reveals bimodal mechano-regulation of cell cycle
https://www.biorxiv.org/content/10.1101/508200v1
Constricted cell migration through tissues is studied using custom-etched pores and shows increased genomic variation during subsequent proliferation.
Categories: biophysics , cancer biology , cell biology
Posted on: 18th May 2019 , updated on: 8th November 2019
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Register hereAlso in the biophysics category:
Biophysical Society Meeting 2020
Some preprints presented at the Biophysical Society Meeting 2020 in San Diego, USA.
| List by | Tessa Sinnige |
ASCB EMBO Annual Meeting 2019
A collection of preprints presented at the 2019 ASCB EMBO Meeting in Washington, DC (December 7-11)
| List by | Madhuja Samaddar, Ramona Jühlen, Amanda Haage, Laura McCormick, Maiko Kitaoka |
EMBL Seeing is Believing – Imaging the Molecular Processes of Life
Preprints discussed at the 2019 edition of Seeing is Believing, at EMBL Heidelberg from the 9th-12th October 2019
| List by | Gautam Dey |
Biomolecular NMR
Preprints related to the application and development of biomolecular NMR spectroscopy
| List by | Reid Alderson |
Also in the cancer biology category:
ASCB EMBO Annual Meeting 2019
A collection of preprints presented at the 2019 ASCB EMBO Meeting in Washington, DC (December 7-11)
| List by | Madhuja Samaddar, Ramona Jühlen, Amanda Haage, Laura McCormick, Maiko Kitaoka |
Lung Disease and Regeneration
This preprint list compiles highlights from the field of lung biology.
| List by | Rob Hynds |
Anticancer agents: Discovery and clinical use
Preprints that describe the discovery of anticancer agents and their clinical use. Includes both small molecules and macromolecules like biologics.
| List by | Zhang-He Goh |
Biophysical Society Annual Meeting 2019
Few of the preprints that were discussed in the recent BPS annual meeting at Baltimore, USA
| List by | Joseph Jose Thottacherry |
Also in the cell biology category:
Planar Cell Polarity – PCP
This preList contains preprints about the latest findings on Planar Cell Polarity (PCP) in various model organisms at the molecular, cellular and tissue levels.
| List by | Ana Dorrego-Rivas |
BioMalPar XVI: Biology and Pathology of the Malaria Parasite
[under construction] Preprints presented at the (fully virtual) EMBL BioMalPar XVI, 17-18 May 2020 #emblmalaria
| List by | Gautam Dey, Samantha Seah |
1
Cell Polarity
Recent research from the field of cell polarity is summarized in this list of preprints. It comprises of studies focusing on various forms of cell polarity ranging from epithelial polarity, planar cell polarity to front-to-rear polarity.
| List by | Yamini Ravichandran |
TAGC 2020
Preprints recently presented at the virtual Allied Genetics Conference, April 22-26, 2020. #TAGC20
| List by | Maiko Kitaoka, Madhuja Samaddar, Miguel V. Almeida, Sejal Davla, Jennifer Ann Black, Gautam Dey |
3D Gastruloids
A curated list of preprints related to Gastruloids (in vitro models of early development obtained by 3D aggregation of embryonic cells)
| List by | Paul Gerald L. Sanchez and Stefano Vianello |
ECFG15 – Fungal biology
Preprints presented at 15th European Conference on Fungal Genetics 17-20 February 2020 Rome
| List by | Hiral Shah |
ASCB EMBO Annual Meeting 2019
A collection of preprints presented at the 2019 ASCB EMBO Meeting in Washington, DC (December 7-11)
| List by | Madhuja Samaddar, Ramona Jühlen, Amanda Haage, Laura McCormick, Maiko Kitaoka |
EMBL Seeing is Believing – Imaging the Molecular Processes of Life
Preprints discussed at the 2019 edition of Seeing is Believing, at EMBL Heidelberg from the 9th-12th October 2019
| List by | Gautam Dey |
Autophagy
Preprints on autophagy and lysosomal degradation and its role in neurodegeneration and disease. Includes molecular mechanisms, upstream signalling and regulation as well as studies on pharmaceutical interventions to upregulate the process.
| List by | Sandra Malmgren Hill |
Lung Disease and Regeneration
This preprint list compiles highlights from the field of lung biology.
| List by | Rob Hynds |
Cellular metabolism
A curated list of preprints related to cellular metabolism at Biorxiv by Pablo Ranea Robles from the Prelights community. Special interest on lipid metabolism, peroxisomes and mitochondria.
| List by | Pablo Ranea Robles |
BSCB/BSDB Annual Meeting 2019
Preprints presented at the BSCB/BSDB Annual Meeting 2019
| List by | Gautam Dey |
MitoList
This list of preprints is focused on work expanding our knowledge on mitochondria in any organism, tissue or cell type, from the normal biology to the pathology.
| List by | Sandra Franco Iborra |
ASCB/EMBO Annual Meeting 2018
This list relates to preprints that were discussed at the recent ASCB conference.
| List by | Gautam Dey, Amanda Haage |
Also in the biophysics category:
A Method to sort heterogenous cell populations based on migration in 2D and 3D environments
| Selected by | Mariana De Niz |
1
LFA-1 signals to promote actin polymerization and upstream migration in T cells
| Selected by | Mariana De Niz |
1
Spatial heterogeneity of cell-matrix adhesive forces predicts human glioblastoma migration
| Selected by | Mariana De Niz |
1
Also in the cancer biology category:
Hyperactive end joining repair mediates resistance to DNA damaging therapy in p53-deficient cells
| Selected by | Matthew Burke |
Engineering T cells to enhance 3D migration through structurally and mechanically complex tumor microenvironments
| Selected by | Ankita Jha |
1
An NKX2-1/ERK/WNT feedback loop modulates gastric identity and response to targeted therapy in lung adenocarcinoma
| Selected by | Catherine Dabrowska |
Also in the cell biology category:
Shoot and root thermomorphogenesis are linked by a developmental trade-off
| Selected by | Alvaro Montiel-Jorda |
A Method to sort heterogenous cell populations based on migration in 2D and 3D environments
| Selected by | Mariana De Niz |
1
Trackosome: a computational toolbox to study the spatiotemporal dynamics of centrosomes, nuclear envelope and cellular membrane
| Selected by | Mariana De Niz |
1