preLights peer support – preprints of interest

How to reach out to contribute (either to suggest preprints OR to write a preLight)? 
preLighters: slack DMs
others: email to girish.kale [at] cos.uni-heidelberg.de OR use the Contact form above. In either case, please add ‘preLights peer support’ in the subject line.

What all information is available in this preList?
This preList contains various details about interesting preprints. The preprints are typically associated with a preLighter, who is willing to play the role of “editor” (for the time being, Girish Kale is the ‘default’ preLighter). When someone has already reached out to highlight a preprint, the name of the writer will appear in the preprint description (if this is (you?), the preprint is still ‘up for grabs’). Each preprint will also carry a bunch of keywords: these could be from the preprint itself, or additional ones based on a quick reading of the manuscript. Additionally, if the preprint is already highlighted through the initiative, then a link to the preLight post will appear below. Once the manuscript is published, there will be a link to the published version of records. If the manuscript is published before a preLight is written about it, then that manuscript will be removed from this preList, as these preprints can’t be highlighted anymore.

How is the preList page organised?
The preprints are sorted reverse-chronologically (latest preprints on the top). Ideally, the preprints at the top should be preferred over the older ones, though, if you find an older preprint to be really interesting, feel free to reach out to check if it can still be added to the preList, or highlighted if already in the preList. Keep in mind that, sooner or later the old preprints will be published, and can’t be highlighted through preLights anymore.

2024 February

Diverse Fgfr1 signaling pathways and endocytic trafficking regulate early mesoderm development

James F Clark, Philippe Soriano

https://www.biorxiv.org/content/10.1101/2024.02.16.580629v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, FGF, mesoderm development, kidney development, cell signaling, cell adhesion, endocytic trafficking

preLight: (not yet highlighted)

manuscript is published: (not yet)

Induction and in silico staging of human gastruloids with neural tube, segmented somites & advanced cell types

Nobuhiko Hamazaki, Wei Yang, Connor Kubo, Chengxiang Qiu, Beth K. Martin, Riddhiman K. Garge, Samuel G. Regalado, Eva Nichols, Choli Lee, Riza M. Daza, Sanjay Srivatsan, Jay Shendure

https://www.biorxiv.org/content/10.1101/2024.02.10.579769v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, human gastruloid, somitogenesis, segmentation, self organization, single cell RNA-seq, WNT, BMP

preLight: (not yet highlighted)

manuscript is published: (not yet)

A tension-induced morphological transition shapes the avian extra-embryonic territory

Arthur Michaut, Alexander Chamolly, Aurelien Villedieu, Francis Corson, Jerome Gros

https://www.biorxiv.org/content/10.1101/2024.02.08.579502v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, extraembryonic tissue

preLight: (not yet highlighted)

manuscript is published: (not yet)

Local and global changes in cell density induce reorganisation of 3D packing in a proliferating epithelium.

Vanessa Barone, Antonio Tagua, Jesus A. Andres-San Roman, Amro Hamdoun, Juan Garrido-Garcia, Deirdre Lyons, Luis M. Escudero

https://www.biorxiv.org/content/10.1101/2024.02.08.579268v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, sea star, echinoderm embryo, morphogenesis, 3D epithelial packing, scutoid, computational modelling, deep-learning, AB-T1.

preLight: (not yet highlighted)

manuscript is published: (not yet)

Compressive stress drives morphogenetic apoptosis

Tatiana Merle, Martine Cazales, Ronan Bouzignac, Brice Ronsin, Christian Rouviere, Magali Suzanne

https://www.biorxiv.org/content/10.1101/2024.02.08.579454v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, leg disk morphogenesis, Drosophila

preLight: (not yet highlighted)

manuscript is published: (not yet)

Eyespots originated multiple times independently across the Lepidoptera

Brian P. F. Hanotte, Beatriz Willink, Antonia Monteiro

https://www.biorxiv.org/content/10.1101/2024.02.07.579046v2

preLighter: (default)

writer: (you?)

keywords: Developmental biology, Lepidoptera, eye spots

preLight: (not yet highlighted)

manuscript is published: (not yet)

Identifying the molecular basis for functional divergence of duplicated SOX factors controlling endoderm formation and left-right patterning in zebrafish

Simaran Johal, Randa Elsayed, Kristen A. Panfilio, Andrew C Nelson

https://www.biorxiv.org/content/10.1101/2024.02.06.579092v2

preLighter: (default)

writer: (you?)

keywords: Developmental biology

preLight: (not yet highlighted)

manuscript is published: (not yet)

Temporal dynamics of BMP/Nodal ratio drive tissue-specific gastrulation morphogenesis

Alyssa A Emig, Megan Hansen, Sandra Grimm, Cristian Coarfa, Nathan D Lord, Margot Kossmann Williams

https://www.biorxiv.org/content/10.1101/2024.02.06.579243v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, Gastrulation, Morphogenesis, Convergent extension, Zebrafish, Nodal, BMP

preLight: (not yet highlighted)

manuscript is published: (not yet)

Drosophila Fog/Cta and T48 pathways have overlapping and distinct contributions to mesoderm invagination

Uzuki Horo, Nat Clarke, Adam C. Martin

https://www.biorxiv.org/content/10.1101/2024.02.02.578601v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, mesoderm invagination, apical constriction

preLight: (not yet highlighted)

manuscript is published: (not yet)

2024 January

Coupling and uncoupling of midline morphogenesis and cell flow in amniote gastrulation

Rieko Asai, Vivek N. Prakash, Shubham Sinha, Manu Prakash, Takashi Mikawa

https://www.biorxiv.org/content/10.1101/2023.05.26.542486v4

preLighter: (default)

writer: (you?)

keywords: Developmental biology, gastrulation, convergent extension movements

preLight: (not yet highlighted)

manuscript is published: (not yet)

A feather star is born: embryonic development and nervous system organization in the crinoid Antedon mediterranea

S. Mercurio, G. Gattoni, G. Scarì, M. Ascagni, B. Barzaghi, M. R. Elphick, E. Benito-Gutiérrez, R. Pennati

https://www.biorxiv.org/content/10.1101/2024.01.30.577964v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, echinoderm development, feather star, embryogenesis, nervous system, apical organ, skeletogenesis, Antedon mediterranea, evo-devo

preLight: (not yet highlighted)

manuscript is published: (not yet)

Hepatoblast iterative apicobasal polarization is regulated by extracellular matrix remodeling

Julien Delpierre, José Ignacio Valenzuela, Matthew Bovyn, Nuno Pimpao Martins, Lenka Belicova, Urska Repnik, Maarten Bebelman, Sarah Seifert, Pierre A Haas, Yannis L Kalaidzidis, Marino Zerial

https://www.biorxiv.org/content/10.1101/2024.01.30.578046v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, mouse liver development, hepatoblast polarity, apical recycling endosome, extracellular matrix, integrins, metalloproteases

preLight: (not yet highlighted)

manuscript is published: (not yet)

PCP Auto Count: A Novel Fiji/ImageJ plug-in for automated quantification of planar cell polarity and cell counting

Kendra L. Stansak, Luke D. Baum, Sumana Ghosh, Punam Thapa, Vineel Vanga, Bradley J. Walters

https://www.biorxiv.org/content/10.1101/2024.01.30.578047v2

preLighter: (default)

writer: (you?)

keywords: Developmental biology, image analysis

preLight: (not yet highlighted)

manuscript is published: (not yet)

Occurrence of non-apical mitoses at the primitive streak, induced by relaxation of actomyosin and acceleration of the cell cycle, contributes to cell delamination during mouse gastrulation

Evangéline Despin-Guitard, Steffen Plunder, Navrita Mathiah, Eric Theveneau, Isabelle Migeotte

https://www.biorxiv.org/content/10.1101/2024.01.24.577096v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, mouse gastrulation, epithelial to mesenchymal transition

preLight: (not yet highlighted)

manuscript is published: (not yet)

PatternJ: an ImageJ toolset for the automated and quantitative analysis of regular spatial patterns found in sarcomeres, axons, somites, and more

Mélina Baheux Blin, Vincent Loreau, Frank Schnorrer, Pierre Mangeol

https://www.biorxiv.org/content/10.1101/2024.01.17.576053v1

preLighter: (default)

writer: (you?)

keywords: Biophysics, image analysis

preLight: (not yet highlighted)

manuscript is published: (not yet)

The Lifeact-EGFP Quail: A New Avian Model For Studying Actin Dynamics In Vivo

https://www.biorxiv.org/content/10.1101/2023.11.19.567639v2

preLighter: (default)

writer: (you?)

keywords: Developmental biology, non-model organisms, transgenics

preLight: (not yet highlighted)

manuscript is published: (not yet)

Establishment of CRISPR/Cas9-based knock-in in a hemimetabolous insect: targeted gene tagging in the cricket Gryllus bimaculatus

Yuji Matsuoka, Taro Nakamura, Takahito Watanabe, Austen A. Barnett, Sayuri Tomonari, Guillem Ylla, Carrie A. Whittle, Sumihare Noji, Taro Mito, Cassandra G. Extavour

https://www.biorxiv.org/content/10.1101/2021.05.10.441399v2

preLighter: (default)

writer: (you?)

keywords: Developmental biology, CRISPR/Cas9, Orthoptera, genome editing, Hox genes, Ultrabithorax, abdominal-A

preLight: (not yet highlighted)

manuscript is published: (not yet)

Glycolysis–Wnt signaling axis tunes developmental timing of embryo segmentation

Hidenobu Miyazawa, Jona Rada, Paul Gerald Layague Sanchez, Emilia Esposito, Daria Bunina, Charles Girardot, Judith Zaugg, Alexander Aulehla

https://www.biorxiv.org/content/10.1101/2024.01.22.576629v2

preLighter: (default)

writer: (you?)

keywords: Developmental biology, glycolysis, metabolism, Wnt signalling, segmentation

preLight: (not yet highlighted)

manuscript is published: (not yet)

A Clock and Wavefront Self-Organizing Model Recreates the Dynamics of Mouse Somitogenesis in-vivo and in-vitro

Julie Klepstad, Luciano Marcon

https://www.biorxiv.org/content/10.1101/2023.01.18.524516v3

preLighter: (default)

writer: (you?)

keywords: Developmental biology, mouse somitogenesis, segmentation, clock and wavefront model, self organization, theoretical modelling

preLight: (not yet highlighted)

manuscript is published: (not yet)

Development and patterning of a highly versatile visual system in spiders

Luis Baudouin Gonzalez, Anna Schoenauer, Amber Harper, Saad Arif, Daniel J Leite, Philip O. M. Steinhoff, Matthias Pechmann, Valeriia Telizhenko, Atal Pande, Carolin Kosiol, Alistair P McGregor, Lauren Sumner-Rooney

https://www.biorxiv.org/content/10.1101/2023.12.22.572789v3

preLighter: (default)

writer: (you?)

keywords: Developmental biology, development and patterning in spiders

preLight: (not yet highlighted)

manuscript is published: (not yet)

Mechanosensitive genomic enhancers potentiate the cellular response to matrix stiffness

Brian D. Cosgrove, Lexi R. Bounds, Carson Key Taylor, Alan L. Su, Anthony J. Rizzo, Alejandro Barrera, Gregory E. Crawford, Brenton D. Hoffman, Charles A. Gersbach

https://www.biorxiv.org/content/10.1101/2024.01.10.574997v1

preLighter: (default)

writer: (you?)

keywords: Genomics

preLight: (not yet highlighted)

manuscript is published: (not yet)

Modularity of the segmentation clock and morphogenesis

James E. Hammond, Ruth Baker, Berta Verd

https://www.biorxiv.org/content/10.1101/2024.01.08.574679v2

preLighter: (default)

writer: (you?)

keywords: Developmental biology, zebrafish, presomitic mesoderm, segmentation, computational model

preLight: (not yet highlighted)

manuscript is published: (not yet)

Single-cell transcriptional dynamics in a living vertebrate

Elizabeth Eck, Bruno Moretti, Brandon H. Schlomann, Jordão Bragantini, Merlin Lange, Xiang Zhao, Shruthi VijayKumar, Guillaume Valentin, Cristina Loureiro, Daniele Soroldoni, Loïc A. Royer, Andrew C. Oates, Hernan G. Garcia

https://www.biorxiv.org/content/10.1101/2024.01.03.574108v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, zebra fish, MS2, single-cell transcriptional readouts

preLight: (not yet highlighted)

manuscript is published: (not yet)

Cooperation between Nodal and FGF signals regulates zebrafish cardiac cell migration and heart morphogenesis

Vanessa Gonzalez, Meagan G. Grant, Makoto Suzuki, Briana Christophers, Jessica Rowland Williams, Rebecca D. Burdine

https://www.biorxiv.org/content/10.1101/2024.01.05.574380v2

preLighter: (default)

writer: (you?)

keywords: Developmental biology, congenital heart defects, left-right asymmetry, cardiac looping, cardiac jogging, Nodal, FGF

preLight: (not yet highlighted)

manuscript is published: (not yet)

A revised single-cell transcriptomic atlas of Xenopus embryo reveals new differentiation dynamics

Kseniya Petrova, Maksym Tretiakov, Aleksandr Kotov, Anne H. Monsoro-Burq, Leonid Peshkin

https://www.biorxiv.org/content/10.1101/2024.01.02.573882v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology

preLight: (not yet highlighted)

manuscript is published: (not yet)

2023 December

Cell density couples tissue mechanics to control the elongation speed of the body axis

Changqing Lu, Joana M. N. Vidigueira, Christopher Chan Jin Jie, Alicja Maksymiuk, Fengzhu Xiong

https://www.biorxiv.org/content/10.1101/2023.12.31.573670v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, segmentation, presomitic mesoderm, cell density, FGF signalling

preLight: (not yet highlighted)

manuscript is published: (not yet)

Learning a conserved mechanism for early neuroectoderm morphogenesis

Matthew F Lefebvre, Jonathan Colen, Nikolas H Claussen, Fridtjof Brauns, Marion K Raich, Noah Mitchell, Michel Fruchart, Vincenzo Vitelli, Sebastian J Streichan

https://www.biorxiv.org/content/10.1101/2023.12.22.573058v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, BMP/Dpp signalling, morphogenesis, machine learning, morphodynamic atlas, Drosophila melanogaster

preLight: (not yet highlighted)

manuscript is published: (not yet)

Apical constriction requires patterned apical surface remodeling to synchronize cellular deformation

Satoshi Yamashita, Shuji Ishihara, François Graner

https://www.biorxiv.org/content/10.1101/2023.12.19.572310v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, tissue folding, endocytosis, mechanical modelling

preLight: (not yet highlighted)

manuscript is published: (not yet)

Live-imaging reveals Coordinated Cell Migration and Cardiac Fate Determination during Mammalian Gastrulation

Shayma Abukar, Peter A. Embacher, Alessandro Ciccarelli, Sunita Varsani-Brown, Jamie A. Dean, James Briscoe, Kenzo Ivanovitch

https://www.biorxiv.org/content/10.1101/2023.12.19.572445v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, heart development, cardiac progenitor live imaging, mouse embryo

preLight: (not yet highlighted)

manuscript is published: (not yet)

EGFR-dependent actomyosin patterning coordinates morphogenetic movements between tissues

D. Nathaniel Clarke, Adam Martin

https://www.biorxiv.org/content/10.1101/2023.12.22.573057v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, mesoderm, ectoderm, cell adhesion, E-cadherin, EGFR signalling, Drosophila

preLight: (not yet highlighted)

manuscript is published: (not yet)

Elasto-Plastic Transition in Epithelial Folding

Aki Teranishi, Misato Mori, Rihoko Ichiki, Satoshi Toda, Go Shioi, Satoru Okuda

https://www.biorxiv.org/content/10.1101/2023.12.19.572470v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, tissue folding, EGFR signalling, epithelial-to-mesenchymal transition, epithelial cell culture

preLight: (not yet highlighted)

manuscript is published: (not yet)

Natural reversal of cavefish heart asymmetry is controlled by Sonic Hedgehog effects on the left-right organizer

Mandy Ng, Li Ma, Janet Shi, William R. Jeffery

https://www.biorxiv.org/content/10.1101/2023.12.13.571559v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, cavefish, heart asymmetry, Sonic Hedgehog, left-right organizer, dand5 asymmetry

preLight: (not yet highlighted)

manuscript is published: (not yet)

Physical constraints during Snowball Earth drive the evolution of multicellularity

William W. Crockett, Jack O. Shaw, Carl Simpson, Christopher P. Kempes

https://www.biorxiv.org/content/10.1101/2023.12.07.570654v1

preLighter: (default)

writer: (you?)

keywords: Evolutionary biology, evolution of multicellularity, molecular and fossil data

preLight: (not yet highlighted)

manuscript is published: (not yet)

Spectral decomposition unlocks ascidian morphogenesis

Joel Dokmegang, Emmanuel Faure, Patrick Lemaire, Ed Munro, Madhav Mani

https://www.biorxiv.org/content/10.1101/2023.08.22.554368v2

preLighter: (default)

writer: (you?)

keywords: Developmental biology, mechanical modelling, ascidian embryonic morphogenesis

preLight: (not yet highlighted)

manuscript is published: (not yet)

Mechanical strengthening of cell-cell adhesion during mouse embryo compaction

Ludmilla de Plater, Julie Firmin, Jean-Léon Maître

https://www.biorxiv.org/content/10.1101/2023.12.07.570568v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, embryo compaction, cell adhesion, E-cadherin, dual pipette aspiration assay, mouse embryos

preLight: (not yet highlighted)

manuscript is published: (not yet)

A temporal allocation of amino acid resources ensures fitness and body allometry

Luca Valzania, Aya Alami, Pierre Léopold

https://www.biorxiv.org/content/10.1101/2023.12.08.570599v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, nutrition, growth, allometry, hexamerin, Drosophila

preLight: (not yet highlighted)

manuscript is published: (not yet)

Revisiting bicoid function: complete inactivation reveals an additional fundamental role in Drosophila egg geometry specification

Stefan Baumgartner

https://www.biorxiv.org/content/10.1101/2023.12.08.570753v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, bicoid, CRISPR, embryo geometry, Drosophila melanogster

preLight: (not yet highlighted)

manuscript is published: (not yet)

Integrated Molecular-Phenotypic Profiling Reveals Metabolic Control of Morphological Variation in Stembryos

Alba Villaronga Luque, Ryan G Savill, Natalia López-Anguita, Adriano Bolondi, Sumit Garai, Seher Ipek Gassaloglu, Aayush Poddar, Aydan Bulut-Karslioglu, Jesse V Veenvliet

https://www.biorxiv.org/content/10.1101/2023.12.04.569921v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, embryo models, gastruloids, morphospace, glycolysis, oxidative phosphorylation, singlecell RNA-seq, machine learning, neuro-mesodermal progenitors, somitogenesis, organoids

preLight: (not yet highlighted)

manuscript is published: (not yet)

2023 November

Fluctuating temperatures exacerbate the effects of nutritional stress during development in Drosophila melanogaster

Brooke Zanco, Juliano Morimoto, Fiona Cockerell, Christen Mirth, Carla M. Sgrò

https://www.biorxiv.org/content/10.1101/2023.11.28.569099v1

preLighter: (default)

writer: (you?)

keywords: Evolutionary biology, Temperature, Nutrition, Local Adaptation, Diel Cycles, Climate Change, Development, Drosophila melanogaster

preLight: (not yet highlighted)

manuscript is published: (not yet)

A mechanical atlas for Ascidian gastrulation

Siqi Liu, Patrick Lemaire, Edwin Munro, Madhav Mani

https://www.biorxiv.org/content/10.1101/2022.11.05.515310v2

preLighter: (default)

writer: (you?)

keywords: Developmental biology, mechanical modelling, force inference techniques, Phallusia mammillata

preLight: (not yet highlighted)

manuscript is published: (not yet)

Modelling variability and heterogeneity of EMT scenarios highlights nuclear positioning and protrusions as main drivers of extrusion

Steffen Plunder, Cathy Danesin, Bruno Glise, Marina A. Ferreira, Sara Merino Aceituno, Eric Theveneau

https://www.biorxiv.org/content/10.1101/2023.11.17.567510v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, EMT, nuclear positioning

preLight: (not yet highlighted)

manuscript is published: (not yet)

Long-term cold selection leads to increased thermal plasticity of male body size and thermal canalization of fecundity in Drosophila melanogaster

Rishav Roy, Aradhya Chattopadhyay, Sreebes Deb Sharma, Aharna Mondal, Payel Biswas, Shampa M. Ghosh

https://www.biorxiv.org/content/10.1101/2023.11.13.566815v2

preLighter: (default)

writer: (you?)

keywords: Evolutionary biology, Thermal plasticity, Thermal adaptation, Experimental evolution, Fecundity, Body size, Canalization, Drosophila melanogaster

preLight: (not yet highlighted)

manuscript is published: (not yet)

Intrinsic self-organization of integrin nanoclusters within focal adhesions is required for cellular mechanotransduction

Kashish Jain, Kyna Yu En Lim, Michael P. Sheetz, Pakorn Kanchanawong, Rishita Changede

https://www.biorxiv.org/content/10.1101/2023.11.20.567975v1

preLighter: (default)

writer: (you?)

keywords: Cell biology, Integrins, nanoclustering, mechanotransduction, mouse embryonic fibroblasts

preLight: (not yet highlighted)

manuscript is published: (not yet)

Nonlinear readout of spatial cues underlies robustness of asymmetric cell division

Nelio T.L. Rodrigues, Tom Bland, KangBo Ng, Nisha Hirani, Nathan W. Goehring

https://www.biorxiv.org/content/10.1101/2023.11.21.568006v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, dosage compensation, robustness, canalization, asymmetric cell division, cell polarity, PAR proteins, C. elegans

preLight: (not yet highlighted)

manuscript is published: (not yet)

Cadherins modulate the self-organizing potential of gastruloids

Alexandre Mayran, Dominique Kolly, Lucille Lopez-Delisle, Yuliia Romaniuk, Maxine Leonardi, Anne-Catherine Cossy, Theo Lacroix, Ana Rita Amândio, Pierre Osteil, Denis Duboule

https://www.biorxiv.org/content/10.1101/2023.11.22.568291v2

preLighter: (default)

writer: (you?)

keywords: Developmental biology, Self-organization, EMT, Pluripotency, Gastruloids, Snai1, Chromatin, Somitogenesis

preLight: (not yet highlighted)

manuscript is published: (not yet)

Membrane potential mediates an ancient mechano-transduction mechanism for multi-cellular homeostasis

Avik Mukherjee, Yanqing Huang, Jens Elgeti, Seungeun Oh, Anjali Rebecca Neliat, Janik Schüttler, Nina Catherine Benites, Xili Liu, Mihail Barboiu, Hugo Stocker, Marc W. Kirschner, Markus Basan

https://www.biorxiv.org/content/10.1101/2023.11.02.565386v1

preLighter: (default)

writer: (you?)

keywords: Cell biology, membrane potential, mechanosensing, tissue density

preLight: (not yet highlighted)

manuscript is published: (not yet)

Exposure to Pseudomonas spp. increases Anopheles gambiae insecticide resistance in a population-dependent manner

Luis M. Silva, Gwendoline Acerbi, Marine Amann, Jacob C. Koella

https://www.biorxiv.org/content/10.1101/2023.11.13.565999v1

preLighter: (default)

writer: (you?)

keywords: Evolutionary biology, insecticide resistance, Pseudomonas, anopheles gambiae

preLight: (not yet highlighted)

manuscript is published: (not yet)

Planar polarized force propagation integrates cell behavior with tissue shaping during convergent extension

Shinuo Weng, John B. Wallingford

https://www.biorxiv.org/content/10.1101/2022.11.08.515701v2

preLighter: (default)

writer: (you?)

keywords: Developmental biology, planar cell polarity, convergent extension movements, force inference, chick embryos

preLight: (not yet highlighted)

manuscript is published: (not yet)

Experimental evolution of multicellularity via cuboidal cell packing in fission yeast

Rozenn M. Pineau, Penelope C. Kahn, Dung T. Lac, Mia Denning, Whitney Wong, William C. Ratcliff, G. Ozan Bozdag

https://www.biorxiv.org/content/10.1101/2023.11.03.565576v1

preLighter: (default)

writer: (you?)

keywords: Evolutionary biology, multicellularity, cuboidal packing, convergent evolution, Schizosaccharomyces pombe

preLight: (not yet highlighted)

manuscript is published: (not yet)

New tools reveal PCP-dependent polarized mechanics in the cortex and cytoplasm of single cells during convergent extension

Shinuo Weng, Caitlin C. Devitt, Bill M. Nyaoga, Anna E. Havnen, José Alvarado, John B. Wallingford

https://www.biorxiv.org/content/10.1101/2023.11.07.566066v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, planar cell polarity, convergent extension movements, force inference

preLight: (not yet highlighted)

manuscript is published: (not yet)

Change in RhoGAP and RhoGEF availability drives transitions in cortical patterning and excitability in Drosophila

Jonathan A. Jackson, Marlis Denk-Lobnig, Katherine A. Kitzinger, Adam C. Martin

https://www.biorxiv.org/content/10.1101/2023.11.06.565883v1

preLighter: (default)

writer: (you?)

keywords: Cell biology, RhoA, actomyosin cortex, excitability, development, Drosophila egg chamber, Drosophila embryo

preLight: (not yet highlighted)

manuscript is published: (not yet)

Allometry of cell types in planarians by single cell transcriptomics

Elena Emili, Alberto Pérez-Posada, Maria D. Christodoulou, Jordi Solana

https://www.biorxiv.org/content/10.1101/2023.11.01.565140v1

preLighter: (default)

writer: (you?)

keywords: Systems biology, allometry, single cell RNA-seq, Planarians

preLight: (not yet highlighted)

manuscript is published: (not yet)

Sea anemone MACPF proteins demonstrate an evolutionary transitional state between venomous and developmental functions

Joachim M Surm, Morani Landau, Yaara Y Columbus-Shenkar, Yehu Moran

https://www.biorxiv.org/content/10.1101/2023.10.30.564692v1

preLighter: (default)

writer: (you?)

keywords: Evolutionary biology, venom proteins, novel function during development, Nematostella vectensis

preLight: (not yet highlighted)

manuscript is published: (not yet)

Nuclear deformation and dynamics of migrating cells in 3D confinement reveal adaptation of pulling and pushing forces

Stefan Stoeberl, Johannes Flommersfeld, Max Kreft, Martin Benoit, Chase Broedersz, Joachim O. Raedler

https://www.biorxiv.org/content/10.1101/2023.10.30.564765v1

preLighter: (default)

writer: (you?)

keywords: Biophysics, mechanosensitivity, Nucleus, Confined Migration, Invasion, Cytoskeleton, Mechanobiology, Confinement Adaptation

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manuscript is published: (not yet)

Hsp90 shapes adaptation by controlling the fitness consequences of regulatory variation

Christopher Jakobson, José Aguilar-Rodríguez, Daniel F Jarosz

https://www.biorxiv.org/content/10.1101/2023.10.30.564848v1

preLighter: (default)

writer: (you?)

keywords: Evolutionary biology, Hsp90, genetic variability, evolutionary selection, adaptation, Saccharomyces cerevisiae

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manuscript is published: (not yet)

2023 October

Atypical Protein Kinase C Promotes its own Asymmetric Localisation by Phosphorylating Cdc42 in Polarising Cells

John Packer, Alicia G. Gubieda, Aaron Brooks, Lars N. Deutz, Iolo Squires, Shona Ellison, Sundar Ram Naganathan, Adam J.M. Wollman, Daniel J. Dickinson, Josana Rodriguez

https://www.biorxiv.org/content/10.1101/2023.10.27.563985v1

preLighter: (default)

writer: (you?)

keywords: Cell biology, asymmetric cell division, cell polarity, cell patterning, embryo axis, PAR proteins, atypical protein kinase C (aPKC), membrane protein complex dynamics, aPKC self-regulatory feedback, actomyosin cortex dynamics, phosphoregulation of CDC-42

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manuscript is published: (not yet)

Rapid life-history evolution reinforces competitive asymmetry between invasive and resident species

Chapuis Elodie, Philippe Jarne, Patrice David

https://www.biorxiv.org/content/10.1101/2023.10.25.563987v1

preLighter: (default)

writer: (you?)

keywords: Evolutionary biology, invasion, competition, asymmetry, character displacement, laboratory, freshwater snails

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manuscript is published: (not yet)

Widespread regulation of the maternal transcriptome by Nanos in Drosophila

Mohammad Marhabaie, Tammy H. Wharton, Sung Yun Kim, Robin P. Wharton

https://www.biorxiv.org/content/10.1101/2023.08.28.555109v3

preLighter: (default)

writer: (you?)

keywords: Developmental biology, Nanos, abdominal segmentation, embryonic patterning, Drosophila

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manuscript is published: (not yet)

Zbtb11 interacts with Otx2 and patterns the anterior neuroectoderm in Xenopus

Yumeko Satou-Kobayashi, Shuji Takahashi, Yoshikazu Haramoto, Makoto Asashima, Masanori Taira

https://www.biorxiv.org/content/10.1101/2023.10.20.563376v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, Anterior neuroectoderm, patterning, zinc finger, Xenopus

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manuscript is published: (not yet)

Ecdysone Orchestrates Notch and Broad Symphony to Craft Epithelial Cell Shape Change

Gaurab Ghosh, Sudipta Halder, Aresh Sahu, Mohit Prasad

https://www.biorxiv.org/content/10.1101/2023.10.20.563225v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, Anterior Follicle cells, EcR, Drosophila oogenesis, Notch, Broad-complex, Zipper

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manuscript is published: (not yet)

PDZ Domains from the Junctional Proteins Afadin and ZO-1 Act as Mechanosensors

Vipul T. Vachharajani, Matthew P. DeJong, Alexander R. Dunn

https://www.biorxiv.org/content/10.1101/2023.09.24.559210v2

preLighter: (default)

writer: (you?)

keywords: Biophysics, mechanosensitivity, cell-cell adhesion, catch-bonds, Afadin, ZO-1, PDZ domain, cytoskeleton, magnetic tweezers

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manuscript is published: (not yet)

Continuously fluctuating selection reveals extreme granularity and parallelism of adaptive tracking

M.C. Bitter, S. Berardi, H. Oken, A. Huynh, P. Schmidt, D.A. Petrov

https://www.biorxiv.org/content/10.1101/2023.10.16.562586v1

preLighter: (default)

writer: (you?)

keywords: Evolutionary biology, adaptative tracking, standing genetic variation, common garden experiments, Drosophila

preLight: (not yet highlighted)

manuscript is published: (not yet)

Genomic Diversity Illuminates the Environmental Adaptation of Drosophila suzukii

Siyuan Feng, Samuel P. DeGrey, Christelle Guédot, Sean D. Schoville, John E. Pool

https://www.biorxiv.org/content/10.1101/2023.07.03.547576v2

preLighter: (default)

writer: (you?)

keywords: Evolutionary biology, environmental adaptation, genotype-environment association, invasion genomics, Drosophila suzukii

preLight: (not yet highlighted)

manuscript is published: (not yet)

Two distinct waves of transcriptome and translatome remodelling drive germline stem cell differentiation

Tamsin J. Samuels, Jinghua Gui, Daniel Gebert, Felipe K. Teixeira

https://www.biorxiv.org/content/10.1101/2023.05.14.540555v3

preLighter: (default)

writer: (you?)

keywords: Developmental biology, germline stem cells, translation efficiency, transcriptome, translatome, Drosophila

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manuscript is published: (not yet)

Dynamic Hippo pathway activity underlies mesenchymal differentiation during lung alveolar morphogenesis

Fatima N. Chaudhry, Nigel S. Michki, Dain L. Shirmer, Sharon Mcgrath-Morrow, Lisa R. Young, David B. Frank, Jarod A. Zepp

https://www.biorxiv.org/content/10.1101/2023.10.17.561252v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, Hippo pathway, lung alveolar morphogenesis, bulk RNA sequencing, mouse model

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manuscript is published: (not yet)

Cut it out: Out-of-plane stresses in cell sheet folding of Volvox embryos

Pierre A. Haas, Stephanie S. M. H. Höhn

https://www.biorxiv.org/content/10.1101/2023.10.17.562736v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, cell sheet folding, tissue elasticity, volvox, non-model species

preLight: (not yet highlighted)

manuscript is published: (not yet)

A morphogenic cascade emerges from the co-evolution of spheroid fluidization and fracturing of multicellular barriers

Selwin Kaixiang Wu, Celestine Z. Ho, Fuqiang Sun, Yuting Lou, Christina Bao-Xian Huang, Jingwei Xiao, Murat Shagirov, Ivan Yow, Jasmine Fei Li Chin, Suzie Verma, Alpha Yap, Yuan Lin, Tetsuya Hiraiwa, Boon Chuan Low

https://www.biorxiv.org/content/10.1101/2023.09.25.559247v3

preLighter: (default)

writer: (you?)

keywords: Cell biology, solid-to-fluid-like transition, cancer spheroid invading mesothelium, tissue fracture and fluidisation, 3D cell culture

preLight: (not yet highlighted)

manuscript is published: (not yet)

Modeling the roles of cohesotaxis, cell-intercalation, and tissue geometry in collective cell migration of Xenopus mesendoderm

Tien Comlekoglu, Bette J. Dzamba, Gustavo G. Pacheco, David R. Shook, T.J. Sego, James A. Glazier, Shayn M. Peirce, Douglas W. DeSimone

https://www.biorxiv.org/content/10.1101/2023.10.16.562601v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, Gastrulation, Agent-Based Model, Tissue Morphogenesis, CompuCell3D, Mechanobiology, Emergent Property

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manuscript is published: (not yet)

Temporal restriction of RNAi reveals breakdown of the segmentation clock is reversible after knock down of primary pair rule genes but not Wnt-signaling in the red flour beetle

Felix Kaufholz, Julia C Ulrich, Muhammad S Hakeemi, Gregor Bucher

https://www.biorxiv.org/content/10.1101/2023.10.15.562380v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, Embryogenesis, Insect segmentation, clock and wavefront/speed gradient model, segmentation breakdown, RNAi, transgenic tool, red flour beetle

preLight: (not yet highlighted)

manuscript is published: (not yet)

Adaptive genomic variation is linked to a climatic gradient in a social wasp

Hannah L Cook, Sara E Miller, Gilbert Giri, Kevin J Loope, Michael J Sheehan, Floria M.K. Uy

https://www.biorxiv.org/content/10.1101/2023.10.12.561994v1

preLighter: (default)

writer: (you?)

keywords: Evolutionary biology, climatic gradient, genomic variation, genotype-environment associations, local adaptation, Mischocyttarus mexicanus, social wasp

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manuscript is published: (not yet)

Tropical high-altitude insects show limited capacity to handle high temperatures

Harshad Vijay Mayekar, Pooran Singh Solanki, Homica Arya, Rajaguru Aradhya, Prashanth Suravajhala, Volker Loeschcke, Subhash Rajpurohit

https://www.biorxiv.org/content/10.1101/2022.09.10.507406v2

preLighter: (default)

writer: (you?)

keywords: Evolutionary biology, Heat, Climate change, Rapid adaptation, High altitudes, Drosophila

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manuscript is published: (not yet)

Scale-independent topological interactions drive the first fate decision in the Drosophila embryo

Woonyung Hur, Arghyadip Mukherjee, Luke Hayden, Ziqi Lu, Anna Chao, Noah P. Mitchell, Sebastian J. Streichan, Massimo Vergassola, Stefano Di Talia

https://www.biorxiv.org/content/10.1101/2023.10.11.561879v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, Embryogenesis, Spindle orientation, Nuclear fate, Microtubule structures, Cell fate determination, Drosophila

preLight: (not yet highlighted)

manuscript is published: (not yet)

Vinculin Antagonizes Branched Actin in Controlling Membrane Protrusion, Cell Migration and Cell Cycle Progression

John James, Artem I. Fokin, Dmitry Y. Guschin, Hong Wang, Anna Polesskaya, Svetlana N. Rubtsova, Christophe Le Clainche, Pascal Silberzan, Alexis M. Gautreau, Stéphane Romero

https://www.biorxiv.org/content/10.1101/2023.10.09.561480v2

preLighter: (default)

writer: (you?)

keywords: Cell biology, Vinculin, Mechanotransducer, Cell adhesions, Arp2/3, Actin networks, Migration, Cell-cell junctions

preLight: (not yet highlighted)

manuscript is published: (not yet)

Visualisation of gene expression within the context of tissues: an X-ray computed tomography-based multimodal approach

Kristaps Kairiss, Natalia Sokolova, Lucie Zilova, Christina Schlagheck, Robert Reinhardt, Tilo Baumbach, Tomas Farago, Thomas van de Kamp, Joachim Wittbrodt, Venera Weinhardt

https://www.biorxiv.org/content/10.1101/2023.10.09.561491v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, multimodal labelling, X-ray computed-tomography, light sheet microscopy, in situ hybridisation, immunofluorescence, rice fish (medaka), organoids

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manuscript is published: (not yet)

Quantitative proteome dynamics across embryogenesis in a model chordate

Alexander N. Frese, Andrea Mariossi, Michael S. Levine, Martin Wühr

https://www.biorxiv.org/content/10.1101/2023.10.04.559613v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, Evolution, gene expression programs, vertebrates, proteome atlas, developmental stages, multi-omics analysis, Transcriptome, Chordates, Vertebrates, Ciona, Xenopus

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manuscript is published: (not yet)

Segmentation in tapeworms as a modified form of flatworm posterior regeneration involving Wnt and Hedgehog signalling

Francesca Jarero, Andrew Baillie, Nick Riddiford, Jimena Montagne, Uriel Koziol, Peter D Olson

https://www.biorxiv.org/content/10.1101/2023.10.02.560491v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, segmentation, anteroposterior patterning, regeneration, tapeworm, Wnt, Hedgehog

preLight: (not yet highlighted)

manuscript is published: (not yet)

2023 September

Local Thermal Adaptation occurs via Modulation of Mitochondrial Activity in Chinook Salmon

Bradford A Dimos, Alex C Lopez, Patricia M. Schulte, Michael P Phelps

https://www.biorxiv.org/content/10.1101/2023.09.28.560008v1

preLighter: (default)

writer: (you?)

keywords: Evolutionary biology, Thermal Adaptation, Mitochondria, metabolism, non-model species

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manuscript is published: (not yet)

Open top multi sample dual view light sheet microscope for live imaging of large multicellular systems

Franziska Moos, Simon Suppinger, Gustavo de Medeiros, Koen Oost, Andrea Boni, Camille Remy, Sera Weevers, Charisios D Tsiairis, Petr Strnad, Prisca Liberali

https://www.biorxiv.org/content/10.1101/2023.09.28.559925v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, light sheet microscopy, high content microscopy, intestinal organoids, gastruloids, live imaging, new imaging techniques

preLight: (not yet highlighted)

manuscript is published: (not yet)

Myocardin-related transcription factors regulate morphogenetic events in vertebrate embryos by controlling F-actin organization and apical constriction

Keiji Itoh, Olga Ossipova, Miho Matsuda, Sergei Y Sokol

https://www.biorxiv.org/content/10.1101/2023.09.27.559818v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, Mrtf, serum response factor, morphogenesis, gastrulation, megakaryoblastic leukemia, Mkl, F-actin, Xenopus embryo, apical constriction, blastopore, neural tube closure, tricellular junctions

preLight: (not yet highlighted)

manuscript is published: (not yet)

Notch signalling plays a critical role in patterning the ventral mesoderm during early embryogenesis in Drosophila melanogaster

Marvel Megaly, Gregory Foran, Arsala Ali, Anel Turgambayeva, Ryan D. Hallam, Aleksandar Necakov

https://www.biorxiv.org/content/10.1101/2023.09.27.558900v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, Notch signalling, Drosophila, mesoderm, morphogenesis, dorso-ventral patterning

preLight: (not yet highlighted)

manuscript is published: (not yet)

Transcriptome analysis reveals temporally regulated genetic networks during Drosophila border cell collective migration

Emily Burghardt, Jessica Rakijas, Antariksh Tyagi, Pralay Majumder, Bradley J.S.C. Olson, Jocelyn A. McDonald

https://www.biorxiv.org/content/10.1101/2023.09.27.559830v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, Collective cell migration, oogenesis, adhesion, morphogenesis, ribosome, RNA-seq, Drosophila

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manuscript is published: (not yet)

Cell proliferation and Notch signaling coordinate the formation of epithelial folds in the Drosophila leg

Alonso Rodriguez, Sergio Cordoba, Daniel Delipe-Cordero, Antonio Baonza, David Miguez, Carlos Estella

https://www.biorxiv.org/content/10.1101/2023.09.28.559944v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, Notch signalling, cell proliferation, morphogenesis, epithelia, Drosophila

preLight: (not yet highlighted)

manuscript is published: (not yet)

Embryogenesis in myrmicine ants combines features of short and long germ-band modes of development

Chi-Chun Fang, Arjuna Rajakumar, Andrew Kenny, Ulrich G. Mueller, Ehab Abouheif, David Stein

https://www.biorxiv.org/content/10.1101/2023.09.19.557849v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, morphogenesis, embryogenesis, segmental patterning, development in non-model organisms, ant species, Hymenoptera

preLight: (not yet highlighted)

manuscript is published: (not yet)

Sensitivity of the timing of Drosophila pupal wing morphogenesis to external perturbations

Romina Piscitello-Gómez, Ali Mahmoud, Natalie A Dye, Suzanne Eaton

https://www.biorxiv.org/content/10.1101/2023.09.22.558969v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, morphogenesis, Drosophila, pupal wing

preLight: (not yet highlighted)

manuscript is published: (not yet)

Strong environmental memory revealed by experimental evolution in static and fluctuating environments

Clare I. Abreu, Shaili Mathur, Dmitri A. Petrov

https://www.biorxiv.org/content/10.1101/2023.09.14.557739v2

preLighter: (default)

writer: (you?)

keywords: Evolutionary biology, laboratory evolution, barcoded yeast lineages, non-additive effects, environmental memory

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manuscript is published: (not yet)

GC content across insect genomes: phylogenetic patterns, causes and consequences

Riccardo G. Kyriacou, Peter O. Mulhair, Peter W. H. Holland

https://www.biorxiv.org/content/10.1101/2023.09.11.557135v1

preLighter: (default)

writer: (you?)

keywords: Evolutionary biology, GC content, phylogenetic patterns, genome biology, coding region

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manuscript is published: (not yet)

An actomyosin network organizes niche morphology and responds to feedback from recruited stem cells

Bailey N. Warder, Kara A. Nelson, Justin Sui, Lauren Anllo, Stephen DiNardo

https://www.biorxiv.org/content/10.1101/2023.09.08.556877v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, morphogenesis, Drosophila, actomyosin networks, stem cells to niche feedback

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manuscript is published: (not yet)

Conserved nucleocytoplasmic density homeostasis drives cellular organization across eukaryotes

Abin Biswas, Omar Muñoz, Kyoohyun Kim, Carsten Hoege, Benjamin M. Lorton, David Shechter, Jochen Guck, Vasily Zaburdaev, Simone Reber

https://www.biorxiv.org/content/10.1101/2023.09.05.556409v1

preLighter: (default)

writer: (you?)

keywords: Biophysics, nucleoplasm and cytoplasm density, nuclear-to-cytoplasmic ratio, C. elegans, label-free biophotonics, theory

preLight: (not yet highlighted)

manuscript is published: (not yet)

Genetic basis of variation in thermal developmental plasticity for Drosophila melanogaster body pigmentation

E Lafuente, D Duneau, P Beldade

https://www.biorxiv.org/content/10.1101/2023.09.03.556093v1

preLighter: (default)

writer: (you?)

keywords: Evolutionary biology, developmental plasticity; thermal melanism; insect coloration; Genome-Wide Association Study (GWAS); Drosophila Genetic Reference Panel (DGRP); seasonal variation

preLight: (not yet highlighted)

manuscript is published: (not yet)

Mechanosensing through talin 1 contributes to tissue mechanical homeostasis

Manasa V.L. Chanduri, Abhishek Kumar, Dar Weiss, Nir Emuna, Igor Barsukov, Muisi Shi, Keiichiro Tanaka, Xinzhe Wang, Amit Datye, Jean Kanyo, Florine Collin, TuKiet Lam, Udo D. Schwarz, Suxia Bai, Timothy Nottoli, Benjamin T Goult, Jay D. Humphrey, Martin A Schwartz

https://www.biorxiv.org/content/10.1101/2023.09.03.556084v2

preLighter: (default)

writer: (you?)

keywords: Cell biology, mechanosensing, tissue mechanical homeostasis, talin, cell-ECM interactions

preLight: (not yet highlighted)

manuscript is published: (not yet)

2023 August

Immigration delays but does not prevent adaptation following environmental change: experimental evidence

Lily F. Durkee, Laure Olazcuaga, Brett A. Melbourne, Ruth A. Hufbauer

https://www.biorxiv.org/content/10.1101/2023.08.31.555763v2

preLighter: (default)

writer: (you?)

keywords: Evolutionary biology, natural selection, evolutionary rescue, dispersal, Tribolium castaneum, gene flow, translocation

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manuscript is published: (not yet)

Modular control of time and space during vertebrate axis segmentation

Ali Seleit, Ian Brettell, Tomas Fitzgerald, Carina Vibe, Felix Loosli, Joachim Wittbrodt, Kiyoshi Naruse, Ewan Birney, Alexander Aulehla

https://www.biorxiv.org/content/10.1101/2023.08.30.555457v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, rice fish (medaka), segmentation tempo, developmental time, developmental constraints, QTL, CRISPR/Cas9, genetic hybridization, scaling

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manuscript is published: (not yet)

Prickle and Ror modulate Dishevelled-Vangl interaction to regulate non-canonical Wnt signaling during convergent extension

Jianbo Wang, Chenbei Chang, Hwa-seon Seo, Deli Yu, Ivan Popov, Jiahui Tao, Allyson Angermeier, Bingdong Sha, Jeffrey D. Axelrod

https://www.biorxiv.org/content/10.1101/2023.08.29.555374v2

preLighter: (default)

writer: (you?)

keywords: Developmental biology, convergent extension, planar cell polarity, non-canonical wnt signalling, Xenopus embryos

preLight: (not yet highlighted)

manuscript is published: (not yet)

Insights into Digit Evolution from a Fate Map Study of the Forearm

JDH Oh, DDZ Saunders, L McTeir, M Jackson, JD Glover, JJ Schoenebeck, LA Lettice, MG Davey

https://www.biorxiv.org/content/10.1101/2023.08.29.555165v2

preLighter: (default)

writer: (you?)

keywords: Developmental biology, digit evolution, morphogenesis, chicken embryos

preLight: (not yet highlighted)

manuscript is published: (not yet)

Morphogen gradients can convey position and time in growing tissues

Roman Vetter, Dagmar Iber

https://www.biorxiv.org/content/10.1101/2023.08.28.555133v2

preLighter: (default)

writer: (you?)

keywords: Developmental biology, tissue patterning, morphogen gradient, time, opposing gradients, neural tube, Sonic hedgehog

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manuscript is published: (not yet)

Morphodynamics of human early brain organoid development

Akanksha Jain, Gilles Gut, Fátima Sanchis-Calleja, Ryoko Okamoto, Simon Streib, Zhisong He, Fides Zenk, Malgorzata Santel, Makiko Seimiya, René Holtackers, Sophie Martina Johanna Jansen, J. Gray Camp, Barbara Treutlein

https://www.biorxiv.org/content/10.1101/2023.08.21.553827v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, brain organoid, light sheet microscopy, single-cell transcriptome, mechanosensing

preLight: (not yet highlighted)

manuscript is published: (not yet)

Nucleotide sharing through gap junctions buffers replication stress

Benjamin Boumard, Gwenn Le Meur, Tania Maalouf, Marwa El-Hajj, Reinhard Bauer, Allison J. Bardin

https://www.biorxiv.org/content/10.1101/2023.08.15.553366v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, gap junctions, metabolism, replication stress, stem cells

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manuscript is published: (not yet)

Successful regeneration of the adult zebrafish retina is dependent on inflammatory signaling

Oliver Bludau, Anke Weber, Viktoria Bosak, Veronika Kuscha, Kristin Dietrich, Stefan Hans, Michael Brand

https://www.biorxiv.org/content/10.1101/2023.08.11.552956v2

preLighter: (default)

writer: (you?)

keywords: Developmental biology, immune suppression, M-CSF, microglia, Müller glia, NF-κB  pathway, retina regeneration, zebrafish

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manuscript is published: (not yet)

The cell adhesion molecule Echinoid promotes tissue survival and separately restricts tissue overgrowth in Drosophila imaginal discs

Danielle C. Spitzer, William Y. Sun, Anthony Rodríguez-Vargas, Iswar K. Hariharan

https://www.biorxiv.org/content/10.1101/2023.08.04.552072v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, echinoid, hippo-pathway, tissue growth regulation, Drosophila imaginal discs

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manuscript is published: (not yet)

Investigating the phylogenetic history of toxin tolerance in mushroom-feeding Drosophila

Theresa Erlenbach, Lauren Haynes, Olivia Fish, Jordan Beveridge, Eunice Bingolo, Sarah-Ashley Giambrone, Grace Kropelin, Stephanie Rudisill, Pablo Chialvo, Laura K. Reed, Kelly A. Dyer, Clare Scott Chialvo

https://www.biorxiv.org/content/10.1101/2023.08.03.551872v1

preLighter: (default)

writer: (you?)

keywords: Evolutionary biology, Ancestral state reconstruction, Amanita mushrooms, phylogenetics, mycophagy, biochemical novelty, toxin tolerance

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manuscript is published: (not yet)

Scaling between cell cycle duration and wing growth is regulated by Fat-Dachsous signaling in Drosophila

Andrew Liu, Jessica O’Connell, Farley Wall, Richard W. Carthew

https://www.biorxiv.org/content/10.1101/2023.08.01.551465v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, Fat-Dachsous, hippo-pathway, tissue growth regulation, Drosophila wing

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manuscript is published: (not yet)

Conserved and novel enhancers regulate expression of Aedes aegypti single-minded in the embryonic ventral midline

Isabella Schember, William Reid, Marc S. Halfon

https://www.biorxiv.org/content/10.1101/2023.08.01.551414v2

preLighter: (default)

writer: (you?)

keywords: Evolutionary biology, enhancer evolution, single minded, nervous system master regulator, embryo development, Aedes aegypti, Drosophila melanogaster,

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manuscript is published: (not yet)

2023 July

Global decoupling of cell differentiation from cell division in early embryo development

Kalki Kukreja, Nikit Patel, Sean G Megason, Allon M Klein

https://www.biorxiv.org/content/10.1101/2023.07.29.551123v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, cell division, cell differentiation, embryo development, single-cell RNAseq, zebrafish

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manuscript is published: (not yet)

Growth directions and stiffness across cell layers determine whether tissues stay smooth or buckle

Avilash S. Yadav, Lilan Hong, Patrick M. Klees, Annamaria Kiss, Xi He, Iselle M. Barrios, Michelle Heeney, Anabella Maria D. Galang, Richard S. Smith, Arezki Boudaoud, Adrienne H.K. Roeder

https://www.biorxiv.org/content/10.1101/2023.07.22.549953v2

preLighter: (default)

writer: (you?)

keywords: Developmental biology, tissue growth regulation, tissue interactions, growth direction, tissue stiffness, Arabidopsis

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manuscript is published: (not yet)

BMP-dependent patterning of ectoderm tissue material properties modulates lateral mesendoderm cell migration during early zebrafish gastrulation

Stefania Tavano, David B. Brückner, Saren Tasciyan, Xin Tong, Roland Kardos, Alexandra Schauer, Robert Hauschild, Carl-Philipp Heisenberg

https://www.biorxiv.org/content/10.1101/2023.07.21.550024v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, gastrulation, tissue material properties, embryo development, zebrafish

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manuscript is published: (not yet)

Cell division angle regulates the tissue mechanics and tunes the amount of cerebellar folding

Amber G. Cook, Taylor V. Bishop, Hannah R. Crowe, Daniel Stevens, Lauren Reine, Alexandra L Joyner, Andrew K Lawton

https://www.biorxiv.org/content/10.1101/2023.07.21.549165v1

preLighter: (default)

writer: (you?)

keywords: Developmental biology, cerebellum, brain folding, cell division angle, tissue mechanics, mouse models

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manuscript is published: (not yet)

Ran-GTP assembles a specialized spindle structure for accurate chromosome segregation in medaka early embryos

Ai Kiyomitsu, Toshiya Nishimura, Shiang Jyi Hwang, Satoshi Ansai, Masato T. Kanemaki, Minoru Tanaka, Tomomi Kiyomitsu

https://www.biorxiv.org/content/10.1101/2023.07.20.549960v1

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writer: (you?)

keywords: Developmental biology, mitotic spindle, chromosome segregation defects, CRISPR knock-in, rice fish (medaka)

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manuscript is published: (not yet)

Coordination of cell cycle and morphogenesis during organ formation

Jeffrey Matthew, Vishakha Vishwakarma, Thao Phuong Le, Ryan A. Agsunod, SeYeon Chung

https://www.biorxiv.org/content/10.1101/2023.07.20.549944v2

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keywords: Developmental biology, salivary gland, Huckebein, endoreplication, endocycle, apoptosis, epithelial tube formation, Drosophila

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Drosophila axis extension is robust to an orthogonal pull by invaginating mesoderm

Claire M Lye, Guy B. Blanchard, Jenny Evans, Alexander Nestor-Bergmann, Bénédicte Sanson

https://www.biorxiv.org/content/10.1101/2023.07.18.549479v1

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keywords: Developmental biology, Mechanical interactions; germband extension; actomyosin cortex; planar polarity; cell neighbour exchanges; convergent extension; live imaging; cell tracking; gastrulation, Drosophila

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manuscript is published: (not yet)

Amphibian segmentation clock models suggest mechanisms of slowed development across increasing genome size and nuclear volume

Alexandra Nicole Taylor, Rachel Lockridge Mueller, Ashok Prasad

https://www.biorxiv.org/content/10.1101/2023.07.16.549220v2

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keywords: Developmental biology, Somitogenesis, cell size, genomic expansion, intron delay, gene expression kinetics, nucleoplasmic diffusion, Xenopus laevis and Ambystoma mexicanum

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manuscript is published: (not yet)

Evolution of compound eye morphology underlies differences in vision between closely related Drosophila species

Alexandra D Buffry, John P Currea, Franziska A Franke, Ravindra Palavalli-Nettimi, Andrew J Bodey, Christoph Rau, Nazanin Samadi, Stefan J Gstöhl, Christian M Schlepütz, Alistair P McGregor, Lauren Sumner-Rooney, Jamie Theobald, Maike Kittelmann

https://www.biorxiv.org/content/10.1101/2023.07.16.549164v1

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writer: (you?)

keywords: Evolutionary biology, eye structure and vision, 3D synchrotron radiation tomography, optomotor response tracking, Drosophila mauritiana and simulans

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manuscript is published: (not yet)

Tissue tension permits β-catenin phosphorylation to drive mesoderm specification in human embryonic stem cells

Nadia M.E. Ayad, Johnathon N. Lakins, Ajinkya Ghagre, Allen J. Ehrlicher, Valerie M. Weaver

https://www.biorxiv.org/content/10.1101/2023.07.14.549074v1

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keywords: Developmental biology, gastrulation, mechanical forces, β-catenin, mesoderm specification, Wnt signaling, human embryonic stem cells, cytoskeletal tension, mechanotransduction, gastruloids, traction force microscopy (TFM)

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Naturally segregating genetic variants contribute to thermal tolerance in a D. melanogaster model system

Patricka A. Williams-Simon, Camille Oster, Jordyn A. Moaton, Ronel Ghidey, Enoch Ng’oma, Kevin M. Middleton, Troy Zars, Elizabeth G. King

https://www.biorxiv.org/content/10.1101/2023.07.06.547110v1

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keywords: Evolutionary biology, QTL, Thermal Tolerance, DSPR, RNA-seq, Gene Expression, RNAi, Complex Traits, Drosophila

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2023 June

Cracked actin filaments as mechanosensitive receptors

Vilmos Zsolnay, Margaret L. Gardel, David R. Kovar, Gregory A. Voth

https://www.biorxiv.org/content/10.1101/2023.06.26.546553v1

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keywords: Biophysics, molecular dynamics simulations, F-actin filaments under tensile strain

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manuscript is published: (not yet)

Patterning and folding of intestinal villi by active mesenchymal dewetting

Tyler R. Huycke, Hikaru Miyazaki, Teemu J. Häkkinen, Vasudha Srivastava, Emilie Barruet, Christopher S. McGinnis, Ali Kalantari, Jake Cornwall-Scoones, Dedeepya Vaka, Qin Zhu, Hyunil Jo, William F. DeGrado, Matt Thomson, Krishna Garikipati, Dario Boffelli, Ophir D. Klein, Zev J. Gartner

https://www.biorxiv.org/content/10.1101/2023.06.25.546328v2

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writer: (you?)

keywords: Developmental biology, tissue folding, intestinal epithelium, tissue interactions, single-cell RNAseq, mouse model

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manuscript is published: (not yet)

A cytokinetic ring-driven cell rotation achieves Hertwig’s rule in early development

Teije C. Middelkoop, Jonas Neipel, Caitlin E. Cornell, Ronald Naumann, Lokesh G. Pimpale, Frank Jülicher, Stephan W. Grill

https://www.biorxiv.org/content/10.1101/2023.06.23.546115v2

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writer: (you?)

keywords: Developmental biology, cell division, theoretical model, actomyosin contractility, C. elegans

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manuscript is published: (not yet)

Evolution of Plasticity in Response to Ethanol between Recently Separated Populations of D. melanogaster with Different Ecological Histories

George Boateng-Sarfo, Franz Scherping, Murad Mammadov, Sarah Signor

https://www.biorxiv.org/content/10.1101/2023.06.22.546145v1

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writer: (you?)

keywords: Evolutionary biology, phenotypic plasticity, ethanol metabolism, adaptation, Drosophila

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2023 May

Distinctive cellular and junctional dynamics independently regulate the rotation and elongation of the internal organ

Mikiko Inaki, Takamasa Higashi, Satoru Okuda, Kenji Matsuno

https://www.biorxiv.org/content/10.1101/2023.05.22.541825v1

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writer: (you?)

keywords: Developmental biology, chiral cell-sliding, cell-intercalation, gut tube rotation, left-right asymmetry, Drosophila

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Apical-driven cell sorting optimised for tissue geometry ensures robust patterning

https://www.biorxiv.org/content/10.1101/2023.05.16.540918v1

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writer: (you?)

keywords: Developmental biology, fate segregation, cell mechanics, cell sorting, cell migration, apical polarity, extracellular matrix, tissue geometry, embryo patterning, robustness, morphogenesis

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Dissecting genetic correlation through recombinant perturbations: the role of developmental bias

Haoran Cai, Kerry Geiler-Samerotte, David L. Des Marais

https://www.biorxiv.org/content/10.1101/2023.05.12.540583v4

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keywords: Evolutionary biology, Genetics, Pleiotropy; Genetic correlation; Developmental bias; Evolvability

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Regeneration from three cellular sources and ectopic mini-retina formation upon neurotoxic retinal degeneration in Xenopus

Parain Karine, Albert Chesneau, Morgane Locker, Caroline Borday, Perron Muriel

https://www.biorxiv.org/content/10.1101/2023.05.12.540545v1

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keywords: Developmental biology, retina, photoreceptor degeneration, cobalt chloride, regeneration, Müller glia, ciliary marginal zone, retinal pigmented epithelium, Xenopus laevis, Xenopus tropicalis

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manuscript is published: (not yet)

Hypoxia delays steroid-induced developmental maturation in Drosophila by suppressing EGF signaling

Michael J Turingan, Tan Li, Jenna Wright, Savraj S Grewal

https://www.biorxiv.org/content/10.1101/2023.05.12.540517v1

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writer: (you?)

keywords: Developmental biology, development in hypoxia, ecdysone signalling, EGFR signalling, Drosophila larvae

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Inverse blebs operate as hydraulic pumps during mouse blastocyst formation

Markus F. Schliffka, Julien G. Dumortier, Diane Pelzer, Arghyadip Mukherjee, Jean-Léon Maître

https://www.biorxiv.org/content/10.1101/2023.05.03.539105v1

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keywords: Developmental biology, lumen formation, fluid pressure, cell adhesion, mouse embryos

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manuscript is published: (not yet)

2023 April

RhoA GEF Mcf2lb regulates rosette integrity during collective cell migration

Hannah M. Olson, Amanda Maxfield, Nicholas L. Calistri, Laura M. Heiser, Alex V. Nechiporuk

https://www.biorxiv.org/content/10.1101/2023.04.19.537573v2

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writer: (you?)

keywords: Developmental biology, collective cell migration, posterior lateral line, cell contractility, zebrafish

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manuscript is published: (not yet)

Bitesize bundles F-actin and influences actin remodeling in syncytial Drosophila embryo development

Anna R. Yeh, Gregory J. Hoeprich, Bruce L. Goode, Adam C. Martin

https://www.biorxiv.org/content/10.1101/2023.04.17.537198v1

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keywords: Developmental biology, syncytial divisions, F-actin regulation, Drosophila

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Evolutionarily conserved role of serotonin signaling in regulating actomyosin contractility during morphogenesis

Sanjay Karki, Mehdi Saadaoui, Valentin Dunsing, Elise Da Silva, Jean-Marc Philippe, Cédric Maurange, Thomas Lecuit

https://www.biorxiv.org/content/10.1101/2023.04.12.535044v1

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keywords: Developmental biology, serotonin signalling, actomyosin contractility regulation, GPCR signalling, gastrulation, Fly and Chicken embryos

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manuscript is published: (not yet)

2023 March

Mitochondrial morphology dynamics and ROS regulate apical polarity and differentiation in Drosophila follicle cells

Bhavin Uttekar, Darshika Tomer, Richa Rikhy

https://www.biorxiv.org/content/10.1101/2023.03.10.532033v1

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writer: (you?)

keywords: Developmental biology, epithelial polarity, mitochondria, ROS, aPKC, Drp1, Opa1, Drosophila

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manuscript is published: (not yet)

2023 February

Desmosome-anchored intermediate filaments facilitate tension-sensitive RhoA signaling for epithelial homeostasis

Bageshri Naimish Nanavati, Ivar Noordstra, Suzie Verma, Kinga Duszyc, Kathleen J. Green, Alpha S. Yap

https://www.biorxiv.org/content/10.1101/2023.02.23.529786v1

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writer: (you?)

keywords: Cell biology, Epithelia, Mechanotransduction, Desmoplakin, Intermediate Filaments, RhoA

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manuscript is published: (not yet)

Geographic variation of the for gene reveals signatures of local adaptation in Drosophila melanogaster

Dylan J. Padilla Perez

https://www.biorxiv.org/content/10.1101/2023.02.19.529142v3

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writer: (you?)

keywords: Evolutionary biology, foraging mode, landscape genetics, polymorphism, heterogeneous environments,  path length, Drosophila

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manuscript is published: (not yet)

Planarians employ diverse and dynamic stem cell microenvironments to support whole-body regeneration

Blair W. Benham-Pyle, Frederick G. Mann Jr., Carolyn E. Brewster, Enya R. Dewars, Dung M. Vuu, Stephanie H. Nowotarski, Carlos Guerrero-Hernández, Seth Malloy, Kate E. Hall, Lucinda E. Maddera, Shiyuan Chen, Jason A. Morrison, Sean A. McKinney, Brian D. Slaughter, Anoja Perera, Alejandro Sánchez Alvarado

https://www.biorxiv.org/content/10.1101/2022.03.20.485025v4

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writer: Rebecca Kern

keywords: Developmental biology, planarians, regeneration, slide-seqv2, stem cell niche

preLight: When it comes to planarian stem cells, it’s not a one-niche-fits-all situation.

manuscript is published: ?

2023 January

2022

PCP and Septins govern the polarized organization of the actin cytoskeleton during convergent extension

Caitlin C Devitt, Shinuo Weng, Vidal D Bejar-Padilla, José Alvarado, John B Wallingford

https://www.biorxiv.org/content/10.1101/2022.06.06.495000v2

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writer: (you?)

keywords: Developmental biology, morphogenesis, planar cell polarity, Septin, actin cytoskeleton, convergent extension, Xenopus

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manuscript is published: (not yet)