I am a postdoc in Michael Way’s group at the Francis Crick Institute, London. I use Vaccinia virus-infected cells as a model to understand how complex signalling networks are organised. My PhD training was in Michael Glotzer’s lab at the University of Chicago, where I studied division plane positioning, primarily in C. elegans embryos. In addition to innate cell signalling mechanisms, I am interested in synthetic signalling and host-pathogen interactions, and like to learn new optogenetics and quantitative imaging methods.
I also enjoy singing slow, melodious songs and dancing to catchy tunes. I routinely perform these talents as well (to the private, appreciative audience of lab microscopes).
Enveloped viruses show increased propensity to cross-species transmission and zoonosis
Bacterial filamentation is an in vivo mechanism for cell-to-cell spreading
Ultrasensitive RNA biosensors for SARS-CoV-2 detection in a simple color and luminescence assay
Optoribogenetic control of regulatory RNA molecules
Evolutionarily diverse LIM domain-containing proteins bind stressed actin filaments through a conserved mechanism
Mechanosensing through direct binding of tensed F-actin by LIM domains
Pick-ya actin: A method to purify actin isoforms with bespoke key post-translational modifications
PP1 and PP2A use opposite phospho-dependencies to control distinct processes at the kinetochore
A pair of E3 ubiquitin ligases compete to regulate filopodial dynamics and axon guidance
Tension on kinetochore substrates is insufficient to prevent Aurora-triggered detachment
Optogenetic dissection of mitotic spindle positioning in vivo
ASCB | EMBO Cell Bio *virtual* 2020
Preprints + open discussions related to work presented at Cell Bio 2020 in December
|Dey Lab et al.
A preprint list to follow the burgeoning field of phase separation in biological processes.
A list of preprints to document our ever-expanding knowledge of this cytoskeletal element - its properties and functions - in diverse contexts.